diff --git a/packages/react-dom-bindings/src/client/ReactFiberConfigDOM.js b/packages/react-dom-bindings/src/client/ReactFiberConfigDOM.js
index bbecbb663566..e4c45ccc4c3f 100644
--- a/packages/react-dom-bindings/src/client/ReactFiberConfigDOM.js
+++ b/packages/react-dom-bindings/src/client/ReactFiberConfigDOM.js
@@ -1435,8 +1435,13 @@ export function applyViewTransitionName(
   className: ?string,
 ): void {
   instance = ((instance: any): HTMLElement);
+  // If the name isn't valid CSS identifier, base64 encode the name instead.
+  // This doesn't let you select it in custom CSS selectors but it does work in current
+  // browsers.
+  const escapedName =
+    CSS.escape(name) !== name ? 'r-' + btoa(name).replace(/=/g, '') : name;
   // $FlowFixMe[prop-missing]
-  instance.style.viewTransitionName = name;
+  instance.style.viewTransitionName = escapedName;
   if (className != null) {
     // $FlowFixMe[prop-missing]
     instance.style.viewTransitionClass = className;
diff --git a/packages/react-dom-bindings/src/server/fizz-instruction-set/ReactDOMFizzInstructionSetInlineCodeStrings.js b/packages/react-dom-bindings/src/server/fizz-instruction-set/ReactDOMFizzInstructionSetInlineCodeStrings.js
index 4e7fb4b73f6f..cac2283236f2 100644
--- a/packages/react-dom-bindings/src/server/fizz-instruction-set/ReactDOMFizzInstructionSetInlineCodeStrings.js
+++ b/packages/react-dom-bindings/src/server/fizz-instruction-set/ReactDOMFizzInstructionSetInlineCodeStrings.js
@@ -8,7 +8,7 @@ export const clientRenderBoundary =
 export const completeBoundary =
   '$RB=[];$RV=function(a){$RT=performance.now();for(var b=0;b<a.length;b+=2){var c=a[b],e=a[b+1];null!==e.parentNode&&e.parentNode.removeChild(e);var f=c.parentNode;if(f){var g=c.previousSibling,h=0;do{if(c&&8===c.nodeType){var d=c.data;if("/$"===d||"/&"===d)if(0===h)break;else h--;else"$"!==d&&"$?"!==d&&"$~"!==d&&"$!"!==d&&"&"!==d||h++}d=c.nextSibling;f.removeChild(c);c=d}while(c);for(;e.firstChild;)f.insertBefore(e.firstChild,c);g.data="$";g._reactRetry&&requestAnimationFrame(g._reactRetry)}}a.length=0};\n$RC=function(a,b){if(b=document.getElementById(b))(a=document.getElementById(a))?(a.previousSibling.data="$~",$RB.push(a,b),2===$RB.length&&("number"!==typeof $RT?requestAnimationFrame($RV.bind(null,$RB)):(a=performance.now(),setTimeout($RV.bind(null,$RB),2300>a&&2E3<a?2300-a:$RT+300-a)))):b.parentNode.removeChild(b)};';
 export const completeBoundaryUpgradeToViewTransitions =
-  '$RV=function(A,g){function k(a,b){var e=a.getAttribute(b);e&&(b=a.style,l.push(a,b.viewTransitionName,b.viewTransitionClass),"auto"!==e&&(b.viewTransitionClass=e),(a=a.getAttribute("vt-name"))||(a="_T_"+K++ +"_"),b.viewTransitionName=a,B=!0)}var B=!1,K=0,l=[];try{var f=document.__reactViewTransition;if(f){f.finished.finally($RV.bind(null,g));return}var m=new Map;for(f=1;f<g.length;f+=2)for(var h=g[f].querySelectorAll("[vt-share]"),d=0;d<h.length;d++){var c=h[d];m.set(c.getAttribute("vt-name"),c)}var u=[];for(h=0;h<g.length;h+=2){var C=g[h],x=C.parentNode;if(x){var v=x.getBoundingClientRect();if(v.left||v.top||v.width||v.height){c=C;for(f=0;c;){if(8===c.nodeType){var r=c.data;if("/$"===r)if(0===f)break;else f--;else"$"!==r&&"$?"!==r&&"$~"!==r&&"$!"!==r||f++}else if(1===c.nodeType){d=c;var D=d.getAttribute("vt-name"),y=m.get(D);k(d,y?"vt-share":"vt-exit");y&&(k(y,"vt-share"),m.set(D,null));var E=d.querySelectorAll("[vt-share]");for(d=0;d<E.length;d++){var F=E[d],G=F.getAttribute("vt-name"),\nH=m.get(G);H&&(k(F,"vt-share"),k(H,"vt-share"),m.set(G,null))}}c=c.nextSibling}for(var I=g[h+1],t=I.firstElementChild;t;)null!==m.get(t.getAttribute("vt-name"))&&k(t,"vt-enter"),t=t.nextElementSibling;c=x;do for(var n=c.firstElementChild;n;){var J=n.getAttribute("vt-update");J&&"none"!==J&&!l.includes(n)&&k(n,"vt-update");n=n.nextElementSibling}while((c=c.parentNode)&&1===c.nodeType&&"none"!==c.getAttribute("vt-update"));u.push.apply(u,I.querySelectorAll(\'img[src]:not([loading="lazy"])\'))}}}if(B){var z=\ndocument.__reactViewTransition=document.startViewTransition({update:function(){A(g);for(var a=[document.documentElement.clientHeight,document.fonts.ready],b={},e=0;e<u.length;b={g:b.g},e++)if(b.g=u[e],!b.g.complete){var p=b.g.getBoundingClientRect();0<p.bottom&&0<p.right&&p.top<window.innerHeight&&p.left<window.innerWidth&&(p=new Promise(function(w){return function(q){w.g.addEventListener("load",q);w.g.addEventListener("error",q)}}(b)),a.push(p))}return Promise.race([Promise.all(a),new Promise(function(w){var q=\nperformance.now();setTimeout(w,2300>q&&2E3<q?2300-q:500)})])},types:[]});z.ready.finally(function(){for(var a=l.length-3;0<=a;a-=3){var b=l[a],e=b.style;e.viewTransitionName=l[a+1];e.viewTransitionClass=l[a+1];""===b.getAttribute("style")&&b.removeAttribute("style")}});z.finished.finally(function(){document.__reactViewTransition===z&&(document.__reactViewTransition=null)});$RB=[];return}}catch(a){}A(g)}.bind(null,$RV);';
+  '$RV=function(A,g){function k(a,b){var e=a.getAttribute(b);e&&(b=a.style,l.push(a,b.viewTransitionName,b.viewTransitionClass),"auto"!==e&&(b.viewTransitionClass=e),(a=a.getAttribute("vt-name"))||(a="_T_"+K++ +"_"),a=CSS.escape(a)!==a?"r-"+btoa(a).replace(/=/g,""):a,b.viewTransitionName=a,B=!0)}var B=!1,K=0,l=[];try{var f=document.__reactViewTransition;if(f){f.finished.finally($RV.bind(null,g));return}var m=new Map;for(f=1;f<g.length;f+=2)for(var h=g[f].querySelectorAll("[vt-share]"),d=0;d<h.length;d++){var c=h[d];m.set(c.getAttribute("vt-name"),c)}var u=[];for(h=0;h<g.length;h+=2){var C=g[h],x=C.parentNode;if(x){var v=x.getBoundingClientRect();if(v.left||v.top||v.width||v.height){c=C;for(f=0;c;){if(8===c.nodeType){var r=c.data;if("/$"===r)if(0===f)break;else f--;else"$"!==r&&"$?"!==r&&"$~"!==r&&"$!"!==r||f++}else if(1===c.nodeType){d=c;var D=d.getAttribute("vt-name"),y=m.get(D);k(d,y?"vt-share":"vt-exit");y&&(k(y,"vt-share"),m.set(D,null));var E=d.querySelectorAll("[vt-share]");\nfor(d=0;d<E.length;d++){var F=E[d],G=F.getAttribute("vt-name"),H=m.get(G);H&&(k(F,"vt-share"),k(H,"vt-share"),m.set(G,null))}}c=c.nextSibling}for(var I=g[h+1],t=I.firstElementChild;t;)null!==m.get(t.getAttribute("vt-name"))&&k(t,"vt-enter"),t=t.nextElementSibling;c=x;do for(var n=c.firstElementChild;n;){var J=n.getAttribute("vt-update");J&&"none"!==J&&!l.includes(n)&&k(n,"vt-update");n=n.nextElementSibling}while((c=c.parentNode)&&1===c.nodeType&&"none"!==c.getAttribute("vt-update"));u.push.apply(u,\nI.querySelectorAll(\'img[src]:not([loading="lazy"])\'))}}}if(B){var z=document.__reactViewTransition=document.startViewTransition({update:function(){A(g);for(var a=[document.documentElement.clientHeight,document.fonts.ready],b={},e=0;e<u.length;b={g:b.g},e++)if(b.g=u[e],!b.g.complete){var p=b.g.getBoundingClientRect();0<p.bottom&&0<p.right&&p.top<window.innerHeight&&p.left<window.innerWidth&&(p=new Promise(function(w){return function(q){w.g.addEventListener("load",q);w.g.addEventListener("error",q)}}(b)),\na.push(p))}return Promise.race([Promise.all(a),new Promise(function(w){var q=performance.now();setTimeout(w,2300>q&&2E3<q?2300-q:500)})])},types:[]});z.ready.finally(function(){for(var a=l.length-3;0<=a;a-=3){var b=l[a],e=b.style;e.viewTransitionName=l[a+1];e.viewTransitionClass=l[a+1];""===b.getAttribute("style")&&b.removeAttribute("style")}});z.finished.finally(function(){document.__reactViewTransition===z&&(document.__reactViewTransition=null)});$RB=[];return}}catch(a){}A(g)}.bind(null,\n$RV);';
 export const completeBoundaryWithStyles =
   '$RM=new Map;$RR=function(n,w,p){function u(q){this._p=null;q()}for(var r=new Map,t=document,h,b,e=t.querySelectorAll("link[data-precedence],style[data-precedence]"),v=[],k=0;b=e[k++];)"not all"===b.getAttribute("media")?v.push(b):("LINK"===b.tagName&&$RM.set(b.getAttribute("href"),b),r.set(b.dataset.precedence,h=b));e=0;b=[];var l,a;for(k=!0;;){if(k){var f=p[e++];if(!f){k=!1;e=0;continue}var c=!1,m=0;var d=f[m++];if(a=$RM.get(d)){var g=a._p;c=!0}else{a=t.createElement("link");a.href=d;a.rel=\n"stylesheet";for(a.dataset.precedence=l=f[m++];g=f[m++];)a.setAttribute(g,f[m++]);g=a._p=new Promise(function(q,x){a.onload=u.bind(a,q);a.onerror=u.bind(a,x)});$RM.set(d,a)}d=a.getAttribute("media");!g||d&&!matchMedia(d).matches||b.push(g);if(c)continue}else{a=v[e++];if(!a)break;l=a.getAttribute("data-precedence");a.removeAttribute("media")}c=r.get(l)||h;c===h&&(h=a);r.set(l,a);c?c.parentNode.insertBefore(a,c.nextSibling):(c=t.head,c.insertBefore(a,c.firstChild))}if(p=document.getElementById(n))p.previousSibling.data=\n"$~";Promise.all(b).then($RC.bind(null,n,w),$RX.bind(null,n,"CSS failed to load"))};';
 export const completeSegment =
diff --git a/packages/react-dom-bindings/src/server/fizz-instruction-set/ReactDOMFizzInstructionSetShared.js b/packages/react-dom-bindings/src/server/fizz-instruction-set/ReactDOMFizzInstructionSetShared.js
index 1f27c7e0cdb7..efe3ad445bc3 100644
--- a/packages/react-dom-bindings/src/server/fizz-instruction-set/ReactDOMFizzInstructionSetShared.js
+++ b/packages/react-dom-bindings/src/server/fizz-instruction-set/ReactDOMFizzInstructionSetShared.js
@@ -130,7 +130,12 @@ export function revealCompletedBoundariesWithViewTransitions(
       const idPrefix = '';
       name = '_' + idPrefix + 'T_' + autoNameIdx++ + '_';
     }
-    elementStyle['viewTransitionName'] = name;
+    // If the name isn't valid CSS identifier, base64 encode the name instead.
+    // This doesn't let you select it in custom CSS selectors but it does work in current
+    // browsers.
+    const escapedName =
+      CSS.escape(name) !== name ? 'r-' + btoa(name).replace(/=/g, '') : name;
+    elementStyle['viewTransitionName'] = escapedName;
     shouldStartViewTransition = true;
   }
   try {
diff --git a/scripts/flow/environment.js b/scripts/flow/environment.js
index f201c2e0e85b..180ee3838dee 100644
--- a/scripts/flow/environment.js
+++ b/scripts/flow/environment.js
@@ -644,3 +644,7 @@ declare module 'rbush' {
     fromJSON(data: any): RBush<T>;
   }
 }
+
+declare class CSS {
+  static escape(str: string): string;
+}