diff --git a/README.md b/README.md
index dd4e5a2..3f9d9f5 100644
--- a/README.md
+++ b/README.md
@@ -20,7 +20,7 @@ without leaving your editor.
   - 📦 **Pre-configured for Popular Tools**: Out-of-the-box support for Claude, Gemini, Grok, Codex, Copilot CLI, and more.
   - ✨ **Context-Aware Prompts**: Automatically include file content, cursor position, and diagnostics in your prompts.
   - 📝 **Prompt Library**: A library of pre-defined prompts for common tasks like explaining code, fixing issues, or writing tests.
-  - 🔄 **Session Persistence**: Keep your CLI sessions alive with `tmux` and `zellij` integration.
+  - 🔄 **Session Persistence**: Keep your CLI sessions alive with `tmux`, `zellij`, and `wezterm` integration.
   - 📂 **Automatic File Watching**: Automatically reloads files in Neovim when they are modified by AI tools.
 
 - **🔌 Extensible and Customizable**
@@ -325,7 +325,7 @@ local defaults = {
       -- terminal: new sessions will be created for each CLI tool and shown in a Neovim terminal
       -- window: when run inside a terminal multiplexer, new sessions will be created in a new tab
       -- split: when run inside a terminal multiplexer, new sessions will be created in a new split
-      -- NOTE: zellij only supports `terminal`
+      -- NOTE: zellij only supports `terminal`, wezterm only supports `split`
       create = "terminal", ---@type "terminal"|"window"|"split"
       split = {
         vertical = true, -- vertical or horizontal split
@@ -930,14 +930,14 @@ Use them together for the complete experience!
 
 ### Terminal sessions not persisting?
 
-Make sure you have tmux or zellij installed and enable the multiplexer:
+Make sure you have tmux, zellij, or wezterm installed and enable the multiplexer:
 
 ```lua
 opts = {
   cli = {
     mux = {
       enabled = true,
-      backend = "tmux", -- or "zellij"
+      backend = "tmux", -- or "zellij" or "wezterm"
     },
   },
 }
diff --git a/lua/sidekick/cli/session/init.lua b/lua/sidekick/cli/session/init.lua
index 1c59892..a7a4f93 100644
--- a/lua/sidekick/cli/session/init.lua
+++ b/lua/sidekick/cli/session/init.lua
@@ -121,7 +121,11 @@ function M.setup()
   end
   M.did_setup = true
   Config.tools() -- load tools, since they may register session backends
-  local session_backends = { tmux = "sidekick.cli.session.tmux", zellij = "sidekick.cli.session.zellij" }
+  local session_backends = {
+    tmux = "sidekick.cli.session.tmux",
+    zellij = "sidekick.cli.session.zellij",
+    wezterm = "sidekick.cli.session.wezterm",
+  }
   for name, mod in pairs(session_backends) do
     if vim.fn.executable(name) == 1 then
       M.register(name, require(mod))
diff --git a/lua/sidekick/cli/session/wezterm.lua b/lua/sidekick/cli/session/wezterm.lua
new file mode 100644
index 0000000..bac00b4
--- /dev/null
+++ b/lua/sidekick/cli/session/wezterm.lua
@@ -0,0 +1,239 @@
+local Config = require("sidekick.config")
+local Util = require("sidekick.util")
+
+---@class sidekick.cli.muxer.WezTerm: sidekick.cli.Session
+---@field wezterm_pane_id number
+local M = {}
+M.__index = M
+M.priority = 70  -- Higher than tmux/zellij for backwards compatibility
+M.external = false  -- Only works from inside WezTerm
+
+--- Initialize WezTerm session, verify we're running inside WezTerm
+function M:init()
+  if not vim.env.WEZTERM_PANE then
+    Util.warn("WezTerm backend requires running inside WezTerm")
+    return
+  end
+
+  if vim.fn.executable("wezterm") ~= 1 then
+    Util.warn("wezterm executable not found in PATH")
+    return
+  end
+end
+
+--- Start a new WezTerm split pane session
+---@return sidekick.cli.terminal.Cmd?
+function M:start()
+  if not vim.env.WEZTERM_PANE then
+    Util.error("Cannot start WezTerm session: not running inside WezTerm")
+    return
+  end
+
+  -- WezTerm only supports split mode (not terminal or window modes)
+  if Config.cli.mux.create ~= "split" then
+    Util.warn({
+      ("WezTerm does not support `opts.cli.mux.create = %q`."):format(Config.cli.mux.create),
+      ("Falling back to %q."):format("split"),
+      "Please update your config.",
+    })
+  end
+
+  -- Build command: wezterm cli split-pane --cwd <cwd> [split options] -- <tool.cmd>
+  local cmd = { "wezterm", "cli", "split-pane", "--cwd", self.cwd }
+
+  -- Add split direction (WezTerm: horizontal = left/right, vertical = top/bottom)
+  -- Note: In WezTerm, "horizontal" means the split line is horizontal (panes side-by-side)
+  if Config.cli.mux.split.vertical then
+    table.insert(cmd, "--bottom")  -- Top-bottom split
+  else
+    table.insert(cmd, "--horizontal")  -- Side-by-side split
+  end
+
+  -- Add split size
+  local size = Config.cli.mux.split.size
+  if size > 0 and size <= 1 then
+    -- Percentage (0-1)
+    table.insert(cmd, "--percent")
+    table.insert(cmd, tostring(math.floor(size * 100)))
+  elseif size > 1 then
+    -- Absolute cells
+    table.insert(cmd, "--cells")
+    table.insert(cmd, tostring(math.floor(size)))
+  end
+
+  -- Add command separator and tool command
+  table.insert(cmd, "--")
+  vim.list_extend(cmd, self.tool.cmd)
+
+  -- Execute and capture pane_id
+  local output = Util.exec(cmd, { notify = true })
+  if not output or #output == 0 then
+    Util.error("Failed to create WezTerm split pane")
+    return
+  end
+
+  -- Parse pane_id (wezterm cli split-pane returns just the pane ID number)
+  self.wezterm_pane_id = tonumber(output[1])
+  if not self.wezterm_pane_id then
+    Util.error(("Failed to parse pane ID from WezTerm output: %s"):format(output[1]))
+    return
+  end
+
+  self.started = true
+
+  -- Save state to track this as a sidekick-created session
+  Util.set_state(tostring(self.wezterm_pane_id), { tool = self.tool.name, cwd = self.cwd })
+
+  Util.info(("Started **%s** in WezTerm pane %d"):format(self.tool.name, self.wezterm_pane_id))
+end
+
+--- Send text to WezTerm pane
+---@param text string
+function M:send(text)
+  if not self.wezterm_pane_id then
+    Util.error("Cannot send text: no pane ID available")
+    return
+  end
+
+  Util.exec({
+    "wezterm",
+    "cli",
+    "send-text",
+    "--pane-id",
+    tostring(self.wezterm_pane_id),
+    "--no-paste",
+    text,
+  }, { notify = false })
+end
+
+--- Submit current input (send newline)
+function M:submit()
+  if not self.wezterm_pane_id then
+    Util.error("Cannot submit: no pane ID available")
+    return
+  end
+
+  Util.exec({
+    "wezterm",
+    "cli",
+    "send-text",
+    "--pane-id",
+    tostring(self.wezterm_pane_id),
+    "--no-paste",
+    "\n",
+  }, { notify = false })
+end
+
+--- Get process ID for a given TTY device
+---@param tty string TTY device path like "/dev/ttys000"
+---@return integer? pid
+local function get_pid_from_tty(tty)
+  if not tty then
+    return nil
+  end
+
+  -- Extract tty name (e.g., "ttys000" from "/dev/ttys000")
+  local tty_name = tty:match("/dev/(.+)$")
+  if not tty_name then
+    return nil
+  end
+
+  -- Use ps to find the process with this tty
+  local lines = Util.exec({ "ps", "-o", "pid=,tty=", "-a" }, { notify = false })
+  if not lines then
+    return nil
+  end
+
+  for _, line in ipairs(lines) do
+    local pid, line_tty = line:match("^%s*(%d+)%s+(%S+)")
+    if line_tty == tty_name and pid then
+      return tonumber(pid)
+    end
+  end
+
+  return nil
+end
+
+--- Check if the WezTerm pane still exists
+---@return boolean
+function M:is_running()
+  if not self.wezterm_pane_id then
+    return false
+  end
+
+  -- List all panes and check if our pane_id exists
+  local output = Util.exec({ "wezterm", "cli", "list", "--format", "json" }, { notify = false })
+  if not output then
+    return false
+  end
+
+  local ok, panes = pcall(vim.json.decode, table.concat(output, "\n"))
+  if not ok or type(panes) ~= "table" then
+    return false
+  end
+
+  for _, pane in ipairs(panes) do
+    if pane.pane_id == self.wezterm_pane_id then
+      return true
+    end
+  end
+
+  return false
+end
+
+--- List all active sidekick sessions in WezTerm panes
+---@return sidekick.cli.session.State[]
+function M.sessions()
+  -- Get all WezTerm panes
+  local output = Util.exec({ "wezterm", "cli", "list", "--format", "json" }, { notify = false })
+  if not output then
+    return {}
+  end
+
+  local ok, panes = pcall(vim.json.decode, table.concat(output, "\n"))
+  if not ok or type(panes) ~= "table" then
+    return {}
+  end
+
+  local ret = {} ---@type sidekick.cli.session.State[]
+  local tools = Config.tools()
+  local Procs = require("sidekick.cli.procs")
+  local procs = Procs.new()
+
+  -- Walk through each pane's processes
+  for _, pane in ipairs(panes) do
+    -- Only include panes that were created by sidekick
+    local state = Util.get_state(tostring(pane.pane_id))
+    if not state then
+      goto continue
+    end
+
+    local pid = get_pid_from_tty(pane.tty_name)
+
+    if pid then
+      procs:walk(pid, function(proc)
+        for _, tool in pairs(tools) do
+          if tool:is_proc(proc) then
+            -- Parse cwd from file:// URL
+            local cwd = pane.cwd and pane.cwd:gsub("^file://", "") or proc.cwd
+
+            ret[#ret + 1] = {
+              id = "wezterm:" .. pane.pane_id,
+              cwd = cwd,
+              tool = tool,
+              wezterm_pane_id = pane.pane_id,
+              pids = Procs.pids(pid),
+            }
+            return true
+          end
+        end
+      end)
+    end
+
+    ::continue::
+  end
+
+  return ret
+end
+
+return M
diff --git a/lua/sidekick/config.lua b/lua/sidekick/config.lua
index 0fb3b09..483a5b5 100644
--- a/lua/sidekick/config.lua
+++ b/lua/sidekick/config.lua
@@ -84,7 +84,7 @@ local defaults = {
       nav = nil,
     },
     ---@class sidekick.cli.Mux
-    ---@field backend? "tmux"|"zellij" Multiplexer backend to persist CLI sessions
+    ---@field backend? "tmux"|"zellij"|"wezterm" Multiplexer backend to persist CLI sessions
     mux = {
       backend = vim.env.ZELLIJ and "zellij" or "tmux", -- default to tmux unless zellij is detected
       enabled = false,
@@ -224,7 +224,7 @@ function M.setup(opts)
     require("sidekick.status").setup()
 
     M.validate("cli.win.layout", { "float", "left", "bottom", "top", "right" })
-    M.validate("cli.mux.backend", { "tmux", "zellij" })
+    M.validate("cli.mux.backend", { "tmux", "zellij", "wezterm" })
     M.validate("cli.mux.create", { "terminal", "window", "split" })
   end)
 end