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💎 📚 metaGEM_paper

Nucleic Acids Research GitHub

Restults generated for the metaGEM publication, where the following datasets were analyzed:

  • 🧪 Small communities of gut microbes from lab cultures
  • 💩 Real gut microbiome samples from Swedish diabetes paper
  • 🪴 Plant-associated soil samples from Chinese rhizobiome study
  • 🌏 Bulk-soil samples from Australian biodiversity analysis
  • 🌊 Ocean water samples from global TARA Oceans expeditions

We provide an individual zenodo repo for each study, where you can find assemblies, contig coverage across all samples in dataset, metagenome assembled genomes (MAGs), ORF-annotated protein bins, and genome-scale metabolic models (GEMs). You can find statistics, summary files, and plots in the bonus.tar.gz folder, including taxonomic annotation of MAGs, as well as genome completeness & contamiantion estimates, among other intermediate results. Alternatively, if all you want is all of the metabolic models, they are collected in a single respository here:

Zenodo

🔍 Overview of datasets

Dataset Data Source Number of Samples Total Size (Gbp) Number of MAGs Generated metaGEM Results
Lab community Publication 48 37 154 Zenodo
Human gut Publication 137 407 4134 Zenodo
Plant associated Publication 6 40 172 Zenodo
Bulk soil Publication 46 596 274 Zenodo
TARA oceans Publication 246 4929 9366 Zenodo (1/2), Zenodo (2/2)
TOTAL - 483 6009 14100 -

🍾 Please cite

If you use metaGEM or results generated by the pipeline please consider citing the publication:

metaGEM: reconstruction of genome scale metabolic models directly from metagenomes
Francisco Zorrilla, Filip Buric, Kiran R Patil, Aleksej Zelezniak
Nucleic Acids Research, 2021; gkab815, https://doi.org/10.1093/nar/gkab815

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Please reach out with any comments, concerns, or discussions regarding metaGEM.

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