diff --git a/src/reader.cpp b/src/reader.cpp
index a6f8794b..14013de7 100644
--- a/src/reader.cpp
+++ b/src/reader.cpp
@@ -30,6 +30,7 @@
 #include "htslib/kstring.h"
 #include "htslib/kseq.h"
 #include "htslib/khash.h"
+#define hts_drand48(void) drand48() //HTSLIB 1.6 compatibility
 #include "htslib/ksort.h"
 
 // Pindel header files