diff --git a/CHANGELOG.md b/CHANGELOG.md
index f696055acbe..ff620cc5acc 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -1,5 +1,11 @@
 # Changelog
 
+## Unreleased
+
+### Fixes
+
+- Crash when logging from certain profiling contexts (#3390)
+
 ## 8.15.1
 
 ### Fixes
diff --git a/Sources/Sentry/SentryProfilingLogging.mm b/Sources/Sentry/SentryProfilingLogging.mm
index 78ca3dd333b..05d74cf239e 100644
--- a/Sources/Sentry/SentryProfilingLogging.mm
+++ b/Sources/Sentry/SentryProfilingLogging.mm
@@ -1,6 +1,8 @@
 #include "SentryProfilingLogging.hpp"
 
-#import "SentryLog.h"
+#if !defined(DEBUG)
+
+#    import "SentryLog.h"
 
 namespace sentry {
 namespace profiling {
@@ -41,3 +43,5 @@
 
 } // namespace profiling
 } // namespace sentry
+
+#endif // !defined(DEBUG)
diff --git a/Sources/Sentry/include/SentryProfilingLogging.hpp b/Sources/Sentry/include/SentryProfilingLogging.hpp
index d86a2949fbb..7e53137134c 100644
--- a/Sources/Sentry/include/SentryProfilingLogging.hpp
+++ b/Sources/Sentry/include/SentryProfilingLogging.hpp
@@ -1,10 +1,12 @@
 #pragma once
 
-#include <cerrno>
-#include <cstring>
-#include <string>
-#include <unistd.h>
-#include <vector>
+#if !defined(DEBUG)
+
+#    include <cerrno>
+#    include <cstring>
+#    include <string>
+#    include <unistd.h>
+#    include <vector>
 
 namespace sentry {
 namespace profiling {
@@ -19,12 +21,25 @@ namespace profiling {
 } // namespace profiling
 } // namespace sentry
 
-#define SENTRY_PROF_LOG_DEBUG(...)                                                                 \
-    sentry::profiling::log(sentry::profiling::LogLevel::Debug, __VA_ARGS__)
-#define SENTRY_PROF_LOG_WARN(...)                                                                  \
-    sentry::profiling::log(sentry::profiling::LogLevel::Warning, __VA_ARGS__)
-#define SENTRY_PROF_LOG_ERROR(...)                                                                 \
-    sentry::profiling::log(sentry::profiling::LogLevel::Error, __VA_ARGS__)
+#    define SENTRY_PROF_LOG_DEBUG(...)                                                             \
+        sentry::profiling::log(sentry::profiling::LogLevel::Debug, __VA_ARGS__)
+#    define SENTRY_PROF_LOG_WARN(...)                                                              \
+        sentry::profiling::log(sentry::profiling::LogLevel::Warning, __VA_ARGS__)
+#    define SENTRY_PROF_LOG_ERROR(...)                                                             \
+        sentry::profiling::log(sentry::profiling::LogLevel::Error, __VA_ARGS__)
+
+#else
+
+// Don't do anything with these in production until we can get a logging solution in place that
+// doesn't use NSLog. We can't use NSLog in these codepaths because it takes a lock, and if the
+// profiler's sampling thread is terminated before it can release that lock, then subsequent
+// attempts to acquire it can cause a crash.
+// See https://github.com/getsentry/sentry-cocoa/issues/3336#issuecomment-1802892052 for more info.
+#    define SENTRY_PROF_LOG_DEBUG(...)
+#    define SENTRY_PROF_LOG_WARN(...)
+#    define SENTRY_PROF_LOG_ERROR(...)
+
+#endif // !defined(DEBUG)
 
 /**
  * Logs the error code returned by executing `statement`, and returns the