diff --git a/api_core/nox.py b/api_core/nox.py
index dacfbb53e74d..7d14ad9befb1 100644
--- a/api_core/nox.py
+++ b/api_core/nox.py
@@ -15,7 +15,8 @@
 from __future__ import absolute_import
 import os
 
-import nox
+# https://github.com/google/importlab/issues/25
+import nox  # pytype: disable=import-error
 
 
 @nox.session
@@ -108,6 +109,19 @@ def lint_setup_py(session):
         'python', 'setup.py', 'check', '--restructuredtext', '--strict')
 
 
+# No 2.7 due to https://github.com/google/importlab/issues/26.
+# No 3.7 because pytype supports up to 3.6 only.
+@nox.session
+def pytype(session):
+  """Run type-checking."""
+  session.interpreter = 'python3.6'
+  session.install('.',
+                  'grpcio >= 1.8.2',
+                  'grpcio-gcp >= 0.2.2',
+                  'pytype >= 2018.9.26')
+  session.run('pytype')
+
+
 @nox.session
 def cover(session):
     """Run the final coverage report.
diff --git a/api_core/setup.cfg b/api_core/setup.cfg
index 2a9acf13daa9..046436b8c99f 100644
--- a/api_core/setup.cfg
+++ b/api_core/setup.cfg
@@ -1,2 +1,9 @@
 [bdist_wheel]
 universal = 1
+
+[pytype]
+python_version = 3.6
+inputs =
+    .
+exclude =
+    tests/