diff --git a/CHANGELOG.md b/CHANGELOG.md
index 1f6f2b799cf9..b30d3bcc039a 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -1,5 +1,6 @@
 ## Main
 
+* [6415](https://github.com/grafana/loki/pull/6415) **salvacorts** Evenly spread queriers across kubernetes nodes.
 * [6410](https://github.com/grafana/loki/pull/6410) **MichelHollands**: Add support for per tenant delete API access enabling.
 * [6372](https://github.com/grafana/loki/pull/6372) **splitice**: Add support for numbers in JSON fields.
 * [6105](https://github.com/grafana/loki/pull/6105) **rutgerke** Export metrics for the Promtail journal target.
diff --git a/docs/sources/upgrading/_index.md b/docs/sources/upgrading/_index.md
index 6a18de94d479..84d07acf8dfe 100644
--- a/docs/sources/upgrading/_index.md
+++ b/docs/sources/upgrading/_index.md
@@ -33,6 +33,11 @@ The output is incredibly verbose as it shows the entire internal config struct u
 
 ### Loki
 
+#### Evenly spread queriers across kubernetes nodes
+
+We now evenly spread queriers across the available kubernetes nodes, but allowing more than one querier to be scheduled into the same node.
+If you want to run at most a single querier per node, set `$._config.querier.use_topology_spread` to false.
+
 #### Implementation of unwrapped `rate` aggregation changed
 
 The implementation of the `rate()` aggregation function changed back to the previous implemention prior to [#5013](https://github.com/grafana/loki/pulls/5013).
diff --git a/production/ksonnet/loki/config.libsonnet b/production/ksonnet/loki/config.libsonnet
index e2f02285decd..8764465fcdfb 100644
--- a/production/ksonnet/loki/config.libsonnet
+++ b/production/ksonnet/loki/config.libsonnet
@@ -47,6 +47,14 @@
       // A higher value will lead to a querier trying to process more requests than there are available
       // cores and will result in scheduling delays.
       concurrency: 4,
+
+      // If use_topology_spread is true, queriers can run on nodes already running queriers but will be
+      // spread through the available nodes using a TopologySpreadConstraints with a max skew
+      // of topology_spread_max_skew.
+      // See: https://kubernetes.io/docs/concepts/workloads/pods/pod-topology-spread-constraints/
+      // If use_topology_spread is false, queriers will not be scheduled on nodes already running queriers.
+      use_topology_spread: true,
+      topology_spread_max_skew: 1,
     },
 
     queryFrontend: {
diff --git a/production/ksonnet/loki/querier.libsonnet b/production/ksonnet/loki/querier.libsonnet
index 0da6fbee01b2..ebf0526c083d 100644
--- a/production/ksonnet/loki/querier.libsonnet
+++ b/production/ksonnet/loki/querier.libsonnet
@@ -26,6 +26,7 @@ local k = import 'ksonnet-util/kausal.libsonnet';
       ]) else {},
 
   local deployment = k.apps.v1.deployment,
+  local topologySpreadConstraints = k.core.v1.topologySpreadConstraint,
 
   querier_deployment: if !$._config.stateful_queriers then
     deployment.new('querier', 3, [$.querier_container]) +
@@ -35,9 +36,18 @@ local k = import 'ksonnet-util/kausal.libsonnet';
       $._config.overrides_configmap_mount_name,
       $._config.overrides_configmap_mount_path,
     ) +
-    k.util.antiAffinity +
     deployment.mixin.spec.strategy.rollingUpdate.withMaxSurge(5) +
-    deployment.mixin.spec.strategy.rollingUpdate.withMaxUnavailable(1)
+    deployment.mixin.spec.strategy.rollingUpdate.withMaxUnavailable(1) +
+    if $._config.querier.use_topology_spread then
+      deployment.spec.template.spec.withTopologySpreadConstraints(
+        // Evenly spread queriers among available nodes.
+        topologySpreadConstraints.labelSelector.withMatchLabels({ name: 'querier' }) +
+        topologySpreadConstraints.withTopologyKey('kubernetes.io/hostname') +
+        topologySpreadConstraints.withWhenUnsatisfiable('ScheduleAnyway') +
+        topologySpreadConstraints.withMaxSkew($._config.querier.topology_spread_max_skew),
+      )
+    else
+      k.util.antiAffinity
   else {},
 
   // PVC for queriers when running as statefulsets