diff --git a/pkg/alertmanager/api_grafana.go b/pkg/alertmanager/api_grafana.go
index 0f52e9c3f07..7c4105ec177 100644
--- a/pkg/alertmanager/api_grafana.go
+++ b/pkg/alertmanager/api_grafana.go
@@ -17,7 +17,9 @@ import (
 
 	"github.com/grafana/mimir/pkg/alertmanager/alertspb"
 	"github.com/grafana/mimir/pkg/util"
+	"github.com/grafana/mimir/pkg/util/globalerror"
 	util_log "github.com/grafana/mimir/pkg/util/log"
+	"github.com/grafana/mimir/pkg/util/validation"
 )
 
 const (
@@ -38,6 +40,17 @@ const (
 	statusError   = "error"
 )
 
+var (
+	maxGrafanaConfigSizeMsgFormat = globalerror.AlertmanagerMaxGrafanaConfigSize.MessageWithPerTenantLimitConfig(
+		errConfigurationTooBig,
+		validation.AlertmanagerMaxGrafanaConfigSizeFlag,
+	)
+	maxGrafanaStateSizeMsgFormat = globalerror.AlertmanagerMaxGrafanaStateSize.MessageWithPerTenantLimitConfig(
+		errStateTooBig,
+		validation.AlertmanagerMaxGrafanaStateSizeFlag,
+	)
+)
+
 type GrafanaAlertmanagerConfig struct {
 	Templates          map[string]string                    `json:"template_files"`
 	AlertmanagerConfig definition.PostableApiAlertingConfig `json:"alertmanager_config"`
@@ -180,10 +193,12 @@ func (am *MultitenantAlertmanager) SetUserGrafanaState(w http.ResponseWriter, r
 	payload, err := io.ReadAll(input)
 	if err != nil {
 		if maxBytesErr := (&http.MaxBytesError{}); errors.As(err, &maxBytesErr) {
-			msg := fmt.Sprintf(errStateTooBig, maxStateSize)
-			level.Warn(logger).Log("msg", msg)
+			level.Warn(logger).Log("msg", fmt.Sprintf(errStateTooBig, maxStateSize))
 			w.WriteHeader(http.StatusBadRequest)
-			util.WriteJSONResponse(w, errorResult{Status: statusError, Error: msg})
+			util.WriteJSONResponse(w, errorResult{
+				Status: statusError,
+				Error:  fmt.Sprintf(maxGrafanaStateSizeMsgFormat, maxStateSize),
+			})
 			return
 		}
 
@@ -336,10 +351,12 @@ func (am *MultitenantAlertmanager) SetUserGrafanaConfig(w http.ResponseWriter, r
 	payload, err := io.ReadAll(input)
 	if err != nil {
 		if maxBytesErr := (&http.MaxBytesError{}); errors.As(err, &maxBytesErr) {
-			msg := fmt.Sprintf(errConfigurationTooBig, maxConfigSize)
-			level.Warn(logger).Log("msg", msg)
+			level.Warn(logger).Log("msg", fmt.Sprintf(errConfigurationTooBig, maxConfigSize))
 			w.WriteHeader(http.StatusBadRequest)
-			util.WriteJSONResponse(w, errorResult{Status: statusError, Error: msg})
+			util.WriteJSONResponse(w, errorResult{
+				Status: statusError,
+				Error:  fmt.Sprintf(maxGrafanaConfigSizeMsgFormat, maxConfigSize),
+			})
 			return
 		}
 
diff --git a/pkg/alertmanager/api_grafana_test.go b/pkg/alertmanager/api_grafana_test.go
index 77c3463165a..7e40ce7da5c 100644
--- a/pkg/alertmanager/api_grafana_test.go
+++ b/pkg/alertmanager/api_grafana_test.go
@@ -342,7 +342,7 @@ func TestMultitenantAlertmanager_SetUserGrafanaConfig(t *testing.T) {
 			expStatusCode: http.StatusBadRequest,
 			expResponseBody: `
 			{
-			"error": "Alertmanager configuration is too big, limit: 10 bytes",
+				"error": "Alertmanager configuration is too big, limit: 10 bytes (err-mimir-alertmanager-max-grafana-config-size). To adjust the related per-tenant limit, configure -alertmanager.max-grafana-config-size-bytes, or contact your service administrator.",
 				"status": "error"
 			}
 			`,
@@ -459,7 +459,7 @@ func TestMultitenantAlertmanager_SetUserGrafanaState(t *testing.T) {
 			expStatusCode: http.StatusBadRequest,
 			expResponseBody: `
 			{
-				"error": "Alertmanager state is too big, limit: 10 bytes",
+				"error": "Alertmanager state is too big, limit: 10 bytes (err-mimir-alertmanager-max-grafana-state-size). To adjust the related per-tenant limit, configure -alertmanager.max-grafana-state-size-bytes, or contact your service administrator.",
 				"status": "error"
 			}
 			`,
diff --git a/pkg/util/globalerror/user.go b/pkg/util/globalerror/user.go
index a0139601bd6..6985ee0fea5 100644
--- a/pkg/util/globalerror/user.go
+++ b/pkg/util/globalerror/user.go
@@ -85,6 +85,10 @@ const (
 	NativeHistogramNegativeBucketCount  ID = "native-histogram-negative-bucket-count"
 	NativeHistogramSpanNegativeOffset   ID = "native-histogram-span-negative-offset"
 	NativeHistogramSpansBucketsMismatch ID = "native-histogram-spans-buckets-mismatch"
+
+	// Alertmanager errors
+	AlertmanagerMaxGrafanaConfigSize ID = "alertmanager-max-grafana-config-size"
+	AlertmanagerMaxGrafanaStateSize  ID = "alertmanager-max-grafana-state-size"
 )
 
 // Message returns the provided msg, appending the error id.
diff --git a/pkg/util/validation/limits.go b/pkg/util/validation/limits.go
index 35c94bc176b..16b1e3685c8 100644
--- a/pkg/util/validation/limits.go
+++ b/pkg/util/validation/limits.go
@@ -59,6 +59,8 @@ const (
 	resultsCacheTTLForOutOfOrderWindowFlag    = "query-frontend.results-cache-ttl-for-out-of-order-time-window"
 	alignQueriesWithStepFlag                  = "query-frontend.align-queries-with-step"
 	QueryIngestersWithinFlag                  = "querier.query-ingesters-within"
+	AlertmanagerMaxGrafanaConfigSizeFlag      = "alertmanager.max-grafana-config-size-bytes"
+	AlertmanagerMaxGrafanaStateSizeFlag       = "alertmanager.max-grafana-state-size-bytes"
 
 	// MinCompactorPartialBlockDeletionDelay is the minimum partial blocks deletion delay that can be configured in Mimir.
 	MinCompactorPartialBlockDeletionDelay = 4 * time.Hour