diff --git a/agent/xdsv2/testdata/listeners/destination/mixed-multi-destination.golden b/agent/xdsv2/testdata/listeners/destination/mixed-multi-destination.golden
index 23dd5e4c6475..eae168bf8aa0 100644
--- a/agent/xdsv2/testdata/listeners/destination/mixed-multi-destination.golden
+++ b/agent/xdsv2/testdata/listeners/destination/mixed-multi-destination.golden
@@ -17,7 +17,7 @@
               "name":  "envoy.filters.network.http_connection_manager",
               "typedConfig":  {
                 "@type":  "type.googleapis.com/envoy.extensions.filters.network.http_connection_manager.v3.HttpConnectionManager",
-                "statPrefix":  "upstream.",
+                "statPrefix":  "upstream.http.api-1.default.default.dc1",
                 "rds":  {
                   "configSource":  {
                     "ads":  {},
diff --git a/agent/xdsv2/testdata/listeners/destination/multiport-l4-and-l7-multiple-implicit-destinations-tproxy.golden b/agent/xdsv2/testdata/listeners/destination/multiport-l4-and-l7-multiple-implicit-destinations-tproxy.golden
index 9cd146e6ef0d..b0477d8310e1 100644
--- a/agent/xdsv2/testdata/listeners/destination/multiport-l4-and-l7-multiple-implicit-destinations-tproxy.golden
+++ b/agent/xdsv2/testdata/listeners/destination/multiport-l4-and-l7-multiple-implicit-destinations-tproxy.golden
@@ -47,7 +47,7 @@
               "name":  "envoy.filters.network.http_connection_manager",
               "typedConfig":  {
                 "@type":  "type.googleapis.com/envoy.extensions.filters.network.http_connection_manager.v3.HttpConnectionManager",
-                "statPrefix":  "upstream.",
+                "statPrefix":  "upstream.http.api-app.default.default.dc1",
                 "rds":  {
                   "configSource":  {
                     "ads":  {},
@@ -140,7 +140,7 @@
               "name":  "envoy.filters.network.http_connection_manager",
               "typedConfig":  {
                 "@type":  "type.googleapis.com/envoy.extensions.filters.network.http_connection_manager.v3.HttpConnectionManager",
-                "statPrefix":  "upstream.",
+                "statPrefix":  "upstream.http.api-app2.default.default.dc1",
                 "rds":  {
                   "configSource":  {
                     "ads":  {},
diff --git a/agent/xdsv2/testdata/listeners/destination/multiport-l4-and-l7-single-implicit-destination-tproxy.golden b/agent/xdsv2/testdata/listeners/destination/multiport-l4-and-l7-single-implicit-destination-tproxy.golden
index 71dec1b4db46..180213b6523c 100644
--- a/agent/xdsv2/testdata/listeners/destination/multiport-l4-and-l7-single-implicit-destination-tproxy.golden
+++ b/agent/xdsv2/testdata/listeners/destination/multiport-l4-and-l7-single-implicit-destination-tproxy.golden
@@ -47,7 +47,7 @@
               "name":  "envoy.filters.network.http_connection_manager",
               "typedConfig":  {
                 "@type":  "type.googleapis.com/envoy.extensions.filters.network.http_connection_manager.v3.HttpConnectionManager",
-                "statPrefix":  "upstream.",
+                "statPrefix":  "upstream.http.api-app.default.default.dc1",
                 "rds":  {
                   "configSource":  {
                     "ads":  {},
diff --git a/agent/xdsv2/testdata/listeners/destination/multiport-l4-and-l7-single-implicit-destination-with-multiple-workloads-tproxy.golden b/agent/xdsv2/testdata/listeners/destination/multiport-l4-and-l7-single-implicit-destination-with-multiple-workloads-tproxy.golden
index 71dec1b4db46..180213b6523c 100644
--- a/agent/xdsv2/testdata/listeners/destination/multiport-l4-and-l7-single-implicit-destination-with-multiple-workloads-tproxy.golden
+++ b/agent/xdsv2/testdata/listeners/destination/multiport-l4-and-l7-single-implicit-destination-with-multiple-workloads-tproxy.golden
@@ -47,7 +47,7 @@
               "name":  "envoy.filters.network.http_connection_manager",
               "typedConfig":  {
                 "@type":  "type.googleapis.com/envoy.extensions.filters.network.http_connection_manager.v3.HttpConnectionManager",
-                "statPrefix":  "upstream.",
+                "statPrefix":  "upstream.http.api-app.default.default.dc1",
                 "rds":  {
                   "configSource":  {
                     "ads":  {},
diff --git a/internal/mesh/internal/controllers/sidecarproxy/builder/destinations.go b/internal/mesh/internal/controllers/sidecarproxy/builder/destinations.go
index f2c4901c89b6..c078c3273e43 100644
--- a/internal/mesh/internal/controllers/sidecarproxy/builder/destinations.go
+++ b/internal/mesh/internal/controllers/sidecarproxy/builder/destinations.go
@@ -248,7 +248,7 @@ func (b *Builder) buildDestination(
 			panic(fmt.Sprintf("it should not be possible to have a tcp protocol here: %v", effectiveProtocol))
 		}
 
-		rb := lb.addL7Router(routeName, "", effectiveProtocol)
+		rb := lb.addL7Router(routeName, statPrefix, effectiveProtocol)
 		if destination.Explicit == nil {
 			rb.addIPAndPortMatch(destination.VirtualIPs, virtualPortNumber)
 		}
@@ -372,7 +372,7 @@ func (b *ListenerBuilder) addL4RouterForDirect(clusterName, statPrefix string) *
 	router := &pbproxystate.Router{}
 
 	if statPrefix == "" {
-		statPrefix = "upstream."
+		statPrefix = fmt.Sprintf("upstream.%s", clusterName)
 	}
 
 	router.Destination = &pbproxystate.Router_L4{
diff --git a/internal/mesh/internal/controllers/sidecarproxy/builder/testdata/destination/mixed-multi-destination.golden b/internal/mesh/internal/controllers/sidecarproxy/builder/testdata/destination/mixed-multi-destination.golden
index ca69db7dfcb0..cbd28e7a70a4 100644
--- a/internal/mesh/internal/controllers/sidecarproxy/builder/testdata/destination/mixed-multi-destination.golden
+++ b/internal/mesh/internal/controllers/sidecarproxy/builder/testdata/destination/mixed-multi-destination.golden
@@ -234,7 +234,7 @@
               "route": {
                 "name": "default/local/default/api-1:http:1.1.1.1:1234"
               },
-              "statPrefix": "upstream."
+              "statPrefix": "upstream.http.api-1.default.default.dc1"
             }
           }
         ]
diff --git a/internal/mesh/internal/controllers/sidecarproxy/builder/testdata/destination/multiport-l4-and-l7-multiple-implicit-destinations-tproxy.golden b/internal/mesh/internal/controllers/sidecarproxy/builder/testdata/destination/multiport-l4-and-l7-multiple-implicit-destinations-tproxy.golden
index f77f427d1995..94e8e1c21577 100644
--- a/internal/mesh/internal/controllers/sidecarproxy/builder/testdata/destination/multiport-l4-and-l7-multiple-implicit-destinations-tproxy.golden
+++ b/internal/mesh/internal/controllers/sidecarproxy/builder/testdata/destination/multiport-l4-and-l7-multiple-implicit-destinations-tproxy.golden
@@ -257,7 +257,7 @@
               "route": {
                 "name": "default/local/default/api-app:http"
               },
-              "statPrefix": "upstream."
+              "statPrefix": "upstream.http.api-app.default.default.dc1"
             },
             "match": {
               "destinationPort": 8080,
@@ -274,7 +274,7 @@
               "route": {
                 "name": "default/local/default/api-app2:http"
               },
-              "statPrefix": "upstream."
+              "statPrefix": "upstream.http.api-app2.default.default.dc1"
             },
             "match": {
               "destinationPort": 8080,
diff --git a/internal/mesh/internal/controllers/sidecarproxy/builder/testdata/destination/multiport-l4-and-l7-single-implicit-destination-tproxy.golden b/internal/mesh/internal/controllers/sidecarproxy/builder/testdata/destination/multiport-l4-and-l7-single-implicit-destination-tproxy.golden
index e6f75c9078fa..479a4e7aefd2 100644
--- a/internal/mesh/internal/controllers/sidecarproxy/builder/testdata/destination/multiport-l4-and-l7-single-implicit-destination-tproxy.golden
+++ b/internal/mesh/internal/controllers/sidecarproxy/builder/testdata/destination/multiport-l4-and-l7-single-implicit-destination-tproxy.golden
@@ -152,7 +152,7 @@
               "route": {
                 "name": "default/local/default/api-app:http"
               },
-              "statPrefix": "upstream."
+              "statPrefix": "upstream.http.api-app.default.default.dc1"
             },
             "match": {
               "destinationPort": 8080,
diff --git a/internal/mesh/internal/controllers/sidecarproxy/builder/testdata/destination/multiport-l4-and-l7-single-implicit-destination-with-multiple-workloads-tproxy.golden b/internal/mesh/internal/controllers/sidecarproxy/builder/testdata/destination/multiport-l4-and-l7-single-implicit-destination-with-multiple-workloads-tproxy.golden
index e6f75c9078fa..479a4e7aefd2 100644
--- a/internal/mesh/internal/controllers/sidecarproxy/builder/testdata/destination/multiport-l4-and-l7-single-implicit-destination-with-multiple-workloads-tproxy.golden
+++ b/internal/mesh/internal/controllers/sidecarproxy/builder/testdata/destination/multiport-l4-and-l7-single-implicit-destination-with-multiple-workloads-tproxy.golden
@@ -152,7 +152,7 @@
               "route": {
                 "name": "default/local/default/api-app:http"
               },
-              "statPrefix": "upstream."
+              "statPrefix": "upstream.http.api-app.default.default.dc1"
             },
             "match": {
               "destinationPort": 8080,
diff --git a/internal/mesh/internal/controllers/xds/testdata/destination/mixed-multi-destination.golden b/internal/mesh/internal/controllers/xds/testdata/destination/mixed-multi-destination.golden
index 2638cf3f806e..3acd9869e51d 100644
--- a/internal/mesh/internal/controllers/xds/testdata/destination/mixed-multi-destination.golden
+++ b/internal/mesh/internal/controllers/xds/testdata/destination/mixed-multi-destination.golden
@@ -285,7 +285,7 @@
             "route": {
               "name": "default/local/default/api-1:http:1.1.1.1:1234"
             },
-            "statPrefix": "upstream."
+            "statPrefix": "upstream.http.api-1.default.default.dc1"
           }
         }
       ]
diff --git a/internal/mesh/internal/controllers/xds/testdata/destination/multiport-l4-and-l7-multiple-implicit-destinations-tproxy.golden b/internal/mesh/internal/controllers/xds/testdata/destination/multiport-l4-and-l7-multiple-implicit-destinations-tproxy.golden
index 0d418fc68059..0158f07aa2c5 100644
--- a/internal/mesh/internal/controllers/xds/testdata/destination/multiport-l4-and-l7-multiple-implicit-destinations-tproxy.golden
+++ b/internal/mesh/internal/controllers/xds/testdata/destination/multiport-l4-and-l7-multiple-implicit-destinations-tproxy.golden
@@ -330,7 +330,7 @@
             "route": {
               "name": "default/local/default/api-app:http"
             },
-            "statPrefix": "upstream."
+            "statPrefix": "upstream.http.api-app.default.default.dc1"
           },
           "match": {
             "destinationPort": 8080,
@@ -347,7 +347,7 @@
             "route": {
               "name": "default/local/default/api-app2:http"
             },
-            "statPrefix": "upstream."
+            "statPrefix": "upstream.http.api-app2.default.default.dc1"
           },
           "match": {
             "destinationPort": 8080,
diff --git a/internal/mesh/internal/controllers/xds/testdata/destination/multiport-l4-and-l7-single-implicit-destination-tproxy.golden b/internal/mesh/internal/controllers/xds/testdata/destination/multiport-l4-and-l7-single-implicit-destination-tproxy.golden
index c465d0ad84b7..3c9d62fb4ea1 100644
--- a/internal/mesh/internal/controllers/xds/testdata/destination/multiport-l4-and-l7-single-implicit-destination-tproxy.golden
+++ b/internal/mesh/internal/controllers/xds/testdata/destination/multiport-l4-and-l7-single-implicit-destination-tproxy.golden
@@ -192,7 +192,7 @@
             "route": {
               "name": "default/local/default/api-app:http"
             },
-            "statPrefix": "upstream."
+            "statPrefix": "upstream.http.api-app.default.default.dc1"
           },
           "match": {
             "destinationPort": 8080,
diff --git a/internal/mesh/internal/controllers/xds/testdata/destination/multiport-l4-and-l7-single-implicit-destination-with-multiple-workloads-tproxy.golden b/internal/mesh/internal/controllers/xds/testdata/destination/multiport-l4-and-l7-single-implicit-destination-with-multiple-workloads-tproxy.golden
index c465d0ad84b7..3c9d62fb4ea1 100644
--- a/internal/mesh/internal/controllers/xds/testdata/destination/multiport-l4-and-l7-single-implicit-destination-with-multiple-workloads-tproxy.golden
+++ b/internal/mesh/internal/controllers/xds/testdata/destination/multiport-l4-and-l7-single-implicit-destination-with-multiple-workloads-tproxy.golden
@@ -192,7 +192,7 @@
             "route": {
               "name": "default/local/default/api-app:http"
             },
-            "statPrefix": "upstream."
+            "statPrefix": "upstream.http.api-app.default.default.dc1"
           },
           "match": {
             "destinationPort": 8080,