diff --git a/.changelog/22575.txt b/.changelog/22575.txt
new file mode 100644
index 00000000000..54344d7e5e9
--- /dev/null
+++ b/.changelog/22575.txt
@@ -0,0 +1,3 @@
+```release-note:enhancement
+resource/aws_s3_bucket: Add additional protection against `object_lock_configuration` causing errors in partitions (e.g., ISO) where not supported
+```
\ No newline at end of file
diff --git a/internal/service/s3/bucket.go b/internal/service/s3/bucket.go
index 805db7f5a48..bc53a63aad6 100644
--- a/internal/service/s3/bucket.go
+++ b/internal/service/s3/bucket.go
@@ -1304,9 +1304,18 @@ func resourceBucketRead(d *schema.ResourceData, meta interface{}) error {
 	}
 
 	// Object Lock configuration.
-	if conf, err := readS3ObjectLockConfiguration(conn, d.Id()); err != nil {
+	conf, err := readS3ObjectLockConfiguration(conn, d.Id())
+
+	// Object lock not supported in all partitions (extra guard, also guards in read func)
+	if err != nil && (meta.(*conns.AWSClient).Partition == endpoints.AwsPartitionID || meta.(*conns.AWSClient).Partition == endpoints.AwsUsGovPartitionID) {
 		return fmt.Errorf("error getting S3 Bucket Object Lock configuration: %s", err)
-	} else {
+	}
+
+	if err != nil {
+		log.Printf("[WARN] Unable to read S3 bucket (%s) object lock configuration: %s", d.Id(), err)
+	}
+
+	if err == nil {
 		if err := d.Set("object_lock_configuration", conf); err != nil {
 			return fmt.Errorf("error setting object_lock_configuration: %s", err)
 		}