diff --git a/.changelog/36054.txt b/.changelog/36054.txt
new file mode 100644
index 00000000000..ae151ddcdf1
--- /dev/null
+++ b/.changelog/36054.txt
@@ -0,0 +1,3 @@
+```release-note:bug
+data-source/aws_instance: Fix `panic: Invalid address to set` related to `root_block_device.0.tags_all`
+```
\ No newline at end of file
diff --git a/internal/service/ec2/ec2_instance.go b/internal/service/ec2/ec2_instance.go
index cd9db6f5f8a..e2e5a1b4992 100644
--- a/internal/service/ec2/ec2_instance.go
+++ b/internal/service/ec2/ec2_instance.go
@@ -1319,7 +1319,7 @@ func resourceInstanceRead(ctx context.Context, d *schema.ResourceData, meta inte
 		return sdkdiag.AppendErrorf(diags, "reading EC2 Instance (%s): %s", d.Id(), err)
 	}
 
-	if err := readBlockDevices(ctx, d, meta, instance); err != nil {
+	if err := readBlockDevices(ctx, d, meta, instance, false); err != nil {
 		return sdkdiag.AppendErrorf(diags, "reading EC2 Instance (%s): %s", d.Id(), err)
 	}
 
@@ -2161,8 +2161,8 @@ func modifyInstanceAttributeWithStopStart(ctx context.Context, conn *ec2.EC2, in
 	return nil
 }
 
-func readBlockDevices(ctx context.Context, d *schema.ResourceData, meta interface{}, instance *ec2.Instance) error {
-	ibds, err := readBlockDevicesFromInstance(ctx, d, meta, instance)
+func readBlockDevices(ctx context.Context, d *schema.ResourceData, meta interface{}, instance *ec2.Instance, ds bool) error {
+	ibds, err := readBlockDevicesFromInstance(ctx, d, meta, instance, ds)
 	if err != nil {
 		return fmt.Errorf("reading block devices: %w", err)
 	}
@@ -2213,7 +2213,7 @@ func readBlockDevices(ctx context.Context, d *schema.ResourceData, meta interfac
 	return nil
 }
 
-func readBlockDevicesFromInstance(ctx context.Context, d *schema.ResourceData, meta interface{}, instance *ec2.Instance) (map[string]interface{}, error) {
+func readBlockDevicesFromInstance(ctx context.Context, d *schema.ResourceData, meta interface{}, instance *ec2.Instance, ds bool) (map[string]interface{}, error) {
 	blockDevices := make(map[string]interface{})
 	blockDevices["ebs"] = make([]map[string]interface{}, 0)
 	blockDevices["root"] = nil
@@ -2279,9 +2279,13 @@ func readBlockDevicesFromInstance(ctx context.Context, d *schema.ResourceData, m
 			bd["device_name"] = aws.StringValue(instanceBd.DeviceName)
 		}
 		if v, ok := d.GetOk("volume_tags"); !ok || v == nil || len(v.(map[string]interface{})) == 0 {
-			tags := KeyValueTags(ctx, vol.Tags).IgnoreAWS().IgnoreConfig(ignoreTagsConfig)
-			bd[names.AttrTags] = tags.RemoveDefaultConfig(defaultTagsConfig).Map()
-			bd[names.AttrTagsAll] = tags.Map()
+			if ds {
+				bd[names.AttrTags] = KeyValueTags(ctx, vol.Tags).IgnoreAWS().IgnoreConfig(ignoreTagsConfig).Map()
+			} else {
+				tags := KeyValueTags(ctx, vol.Tags).IgnoreAWS().IgnoreConfig(ignoreTagsConfig)
+				bd[names.AttrTags] = tags.RemoveDefaultConfig(defaultTagsConfig).Map()
+				bd[names.AttrTagsAll] = tags.Map()
+			}
 		}
 
 		if blockDeviceIsRoot(instanceBd, instance) {
diff --git a/internal/service/ec2/ec2_instance_data_source.go b/internal/service/ec2/ec2_instance_data_source.go
index ecc11abd043..09733231d14 100644
--- a/internal/service/ec2/ec2_instance_data_source.go
+++ b/internal/service/ec2/ec2_instance_data_source.go
@@ -21,6 +21,7 @@ import (
 	"github.com/hashicorp/terraform-provider-aws/internal/errs/sdkdiag"
 	tftags "github.com/hashicorp/terraform-provider-aws/internal/tags"
 	"github.com/hashicorp/terraform-provider-aws/internal/tfresource"
+	"github.com/hashicorp/terraform-provider-aws/names"
 )
 
 // @SDKDataSource("aws_instance")
@@ -98,7 +99,7 @@ func DataSourceInstance() *schema.Resource {
 							Type:     schema.TypeString,
 							Computed: true,
 						},
-						"tags": tftags.TagsSchemaComputed(),
+						names.AttrTags: tftags.TagsSchemaComputed(),
 						"throughput": {
 							Type:     schema.TypeInt,
 							Computed: true,
@@ -332,7 +333,7 @@ func DataSourceInstance() *schema.Resource {
 							Type:     schema.TypeString,
 							Computed: true,
 						},
-						"tags": tftags.TagsSchemaComputed(),
+						names.AttrTags: tftags.TagsSchemaComputed(),
 						"throughput": {
 							Type:     schema.TypeInt,
 							Computed: true,
@@ -549,7 +550,7 @@ func instanceDescriptionAttributes(ctx context.Context, d *schema.ResourceData,
 	}
 
 	// Block devices
-	if err := readBlockDevices(ctx, d, meta, instance); err != nil {
+	if err := readBlockDevices(ctx, d, meta, instance, true); err != nil {
 		return fmt.Errorf("reading EC2 Instance (%s): %w", aws.StringValue(instance.InstanceId), err)
 	}
 	if _, ok := d.GetOk("ephemeral_block_device"); !ok {
diff --git a/internal/service/ec2/ec2_spot_instance_request.go b/internal/service/ec2/ec2_spot_instance_request.go
index 0cb13a8c114..f8226a6e1ce 100644
--- a/internal/service/ec2/ec2_spot_instance_request.go
+++ b/internal/service/ec2/ec2_spot_instance_request.go
@@ -317,7 +317,7 @@ func readInstance(ctx context.Context, d *schema.ResourceData, meta interface{})
 			"host": *instance.PrivateIpAddress,
 		})
 	}
-	if err := readBlockDevices(ctx, d, meta, instance); err != nil {
+	if err := readBlockDevices(ctx, d, meta, instance, false); err != nil {
 		return sdkdiag.AppendFromErr(diags, err)
 	}