diff --git a/sycl/plugins/cuda/pi_cuda.cpp b/sycl/plugins/cuda/pi_cuda.cpp
index fc801df260c93..a5749f4ca0cbd 100644
--- a/sycl/plugins/cuda/pi_cuda.cpp
+++ b/sycl/plugins/cuda/pi_cuda.cpp
@@ -4164,6 +4164,9 @@ pi_result cuda_piextUSMHostAlloc(void **result_ptr, pi_context context,
     result = error;
   }
 
+  assert(alignment == 0 ||
+         (result == PI_SUCCESS &&
+          reinterpret_cast<std::uintptr_t>(*result_ptr) % alignment == 0));
   return result;
 }
 
@@ -4185,6 +4188,9 @@ pi_result cuda_piextUSMDeviceAlloc(void **result_ptr, pi_context context,
     result = error;
   }
 
+  assert(alignment == 0 ||
+         (result == PI_SUCCESS &&
+          reinterpret_cast<std::uintptr_t>(*result_ptr) % alignment == 0));
   return result;
 }
 
@@ -4207,6 +4213,9 @@ pi_result cuda_piextUSMSharedAlloc(void **result_ptr, pi_context context,
     result = error;
   }
 
+  assert(alignment == 0 ||
+         (result == PI_SUCCESS &&
+          reinterpret_cast<std::uintptr_t>(*result_ptr) % alignment == 0));
   return result;
 }
 
diff --git a/sycl/plugins/level_zero/pi_level_zero.cpp b/sycl/plugins/level_zero/pi_level_zero.cpp
index efbf971d6945b..a970ef387faa8 100644
--- a/sycl/plugins/level_zero/pi_level_zero.cpp
+++ b/sycl/plugins/level_zero/pi_level_zero.cpp
@@ -4674,6 +4674,8 @@ pi_result piextUSMHostAlloc(void **ResultPtr, pi_context Context,
   ZE_CALL(
       zeMemAllocHost(Context->ZeContext, &ZeDesc, Size, Alignment, ResultPtr));
 
+  assert(Alignment == 0 ||
+         reinterpret_cast<std::uintptr_t>(*ResultPtr) % Alignment == 0);
   return PI_SUCCESS;
 }
 
@@ -4700,6 +4702,8 @@ pi_result USMDeviceAllocImpl(void **ResultPtr, pi_context Context,
   ZE_CALL(zeMemAllocDevice(Context->ZeContext, &ZeDesc, Size, Alignment,
                            Device->ZeDevice, ResultPtr));
 
+  assert(Alignment == 0 ||
+         reinterpret_cast<std::uintptr_t>(*ResultPtr) % Alignment == 0);
   return PI_SUCCESS;
 }
 
@@ -4721,6 +4725,8 @@ pi_result USMSharedAllocImpl(void **ResultPtr, pi_context Context,
   ZE_CALL(zeMemAllocShared(Context->ZeContext, &ZeDevDesc, &ZeHostDesc, Size,
                            Alignment, Device->ZeDevice, ResultPtr));
 
+  assert(Alignment == 0 ||
+         reinterpret_cast<std::uintptr_t>(*ResultPtr) % Alignment == 0);
   return PI_SUCCESS;
 }
 
diff --git a/sycl/plugins/opencl/pi_opencl.cpp b/sycl/plugins/opencl/pi_opencl.cpp
index 1aae5013a92a8..6a65cc6e9962d 100644
--- a/sycl/plugins/opencl/pi_opencl.cpp
+++ b/sycl/plugins/opencl/pi_opencl.cpp
@@ -713,6 +713,9 @@ pi_result piextUSMHostAlloc(void **result_ptr, pi_context context,
 
   *result_ptr = Ptr;
 
+  assert(alignment == 0 ||
+         (RetVal == PI_SUCCESS &&
+          reinterpret_cast<std::uintptr_t>(*result_ptr) % alignment == 0));
   return RetVal;
 }
 
@@ -746,6 +749,9 @@ pi_result piextUSMDeviceAlloc(void **result_ptr, pi_context context,
 
   *result_ptr = Ptr;
 
+  assert(alignment == 0 ||
+         (RetVal == PI_SUCCESS &&
+          reinterpret_cast<std::uintptr_t>(*result_ptr) % alignment == 0));
   return RetVal;
 }
 
@@ -779,6 +785,9 @@ pi_result piextUSMSharedAlloc(void **result_ptr, pi_context context,
 
   *result_ptr = Ptr;
 
+  assert(alignment == 0 ||
+         (RetVal == PI_SUCCESS &&
+          reinterpret_cast<std::uintptr_t>(*result_ptr) % alignment == 0));
   return RetVal;
 }