diff --git a/compiler/packages/babel-plugin-react-compiler/src/Validation/ValidateNoRefAccessInRender.ts b/compiler/packages/babel-plugin-react-compiler/src/Validation/ValidateNoRefAccessInRender.ts
index abbb7d847698..b0961f5fd7e9 100644
--- a/compiler/packages/babel-plugin-react-compiler/src/Validation/ValidateNoRefAccessInRender.ts
+++ b/compiler/packages/babel-plugin-react-compiler/src/Validation/ValidateNoRefAccessInRender.ts
@@ -354,6 +354,7 @@ function validateNoRefAccessInRenderImpl(
   }
 
   const interpolatedAsJsx = new Set<IdentifierId>();
+  const usedAsEventHandlerProp = new Set<IdentifierId>();
   for (const block of fn.body.blocks.values()) {
     for (const instr of block.instructions) {
       const {value} = instr;
@@ -363,6 +364,27 @@ function validateNoRefAccessInRenderImpl(
             interpolatedAsJsx.add(child.identifier.id);
           }
         }
+        if (value.kind === 'JsxExpression') {
+          /*
+           * Track identifiers used as event handler props on built-in DOM elements.
+           * We only allow this optimization for native DOM elements because their
+           * event handlers are guaranteed by React to only execute in response to
+           * events, never during render. Custom components could technically call
+           * their onFoo props during render, which would violate ref access rules.
+           */
+          if (value.tag.kind === 'BuiltinTag') {
+            for (const prop of value.props) {
+              if (
+                prop.kind === 'JsxAttribute' &&
+                prop.name.startsWith('on') &&
+                prop.name.length > 2 &&
+                prop.name[2] === prop.name[2].toUpperCase()
+              ) {
+                usedAsEventHandlerProp.add(prop.place.identifier.id);
+              }
+            }
+          }
+        }
       }
     }
   }
@@ -519,6 +541,9 @@ function validateNoRefAccessInRenderImpl(
              */
             if (!didError) {
               const isRefLValue = isUseRefType(instr.lvalue.identifier);
+              const isUsedAsEventHandler = usedAsEventHandlerProp.has(
+                instr.lvalue.identifier.id,
+              );
               for (const operand of eachInstructionValueOperand(instr.value)) {
                 /**
                  * By default we check that function call operands are not refs,
@@ -560,6 +585,25 @@ function validateNoRefAccessInRenderImpl(
                    * render function which attempts to obey the rules.
                    */
                   validateNoRefValueAccess(errors, env, operand);
+                } else if (isUsedAsEventHandler) {
+                  /**
+                   * Special case: the lvalue is used as an event handler prop
+                   * on a built-in DOM element
+                   *
+                   * For example `<form onSubmit={handleSubmit(onSubmit)}>`. Here
+                   * handleSubmit is wrapping onSubmit to create an event handler.
+                   * Functions passed to event handler wrappers can safely access
+                   * refs because built-in DOM event handlers are guaranteed by React
+                   * to only execute in response to actual events, never during render.
+                   *
+                   * We only allow this for built-in DOM elements (not custom components)
+                   * because custom components could technically call their onFoo props
+                   * during render, which would violate ref access rules.
+                   *
+                   * We allow passing functions with ref access to these wrappers,
+                   * but still validate that direct ref values aren't passed.
+                   */
+                  validateNoDirectRefValueAccess(errors, operand, env);
                 } else {
                   validateNoRefPassedToFunction(
                     errors,
diff --git a/compiler/packages/babel-plugin-react-compiler/src/__tests__/fixtures/compiler/allow-ref-access-in-async-event-handler-wrapper.expect.md b/compiler/packages/babel-plugin-react-compiler/src/__tests__/fixtures/compiler/allow-ref-access-in-async-event-handler-wrapper.expect.md
new file mode 100644
index 000000000000..c3d65a42e951
--- /dev/null
+++ b/compiler/packages/babel-plugin-react-compiler/src/__tests__/fixtures/compiler/allow-ref-access-in-async-event-handler-wrapper.expect.md
@@ -0,0 +1,148 @@
+
+## Input
+
+```javascript
+// @validateRefAccessDuringRender
+import {useRef} from 'react';
+
+// Simulates react-hook-form's handleSubmit
+function handleSubmit<T>(callback: (data: T) => void | Promise<void>) {
+  return (event: any) => {
+    event.preventDefault();
+    callback({} as T);
+  };
+}
+
+// Simulates an upload function
+async function upload(file: any): Promise<{blob: {url: string}}> {
+  return {blob: {url: 'https://example.com/file.jpg'}};
+}
+
+interface SignatureRef {
+  toFile(): any;
+}
+
+function Component() {
+  const ref = useRef<SignatureRef>(null);
+
+  const onSubmit = async (value: any) => {
+    // This should be allowed: accessing ref.current in an async event handler
+    // that's wrapped and passed to onSubmit prop
+    let sigUrl: string;
+    if (value.hasSignature) {
+      const {blob} = await upload(ref.current?.toFile());
+      sigUrl = blob?.url || '';
+    } else {
+      sigUrl = value.signature;
+    }
+    console.log('Signature URL:', sigUrl);
+  };
+
+  return (
+    <form onSubmit={handleSubmit(onSubmit)}>
+      <input type="text" name="signature" />
+      <button type="submit">Submit</button>
+    </form>
+  );
+}
+
+export const FIXTURE_ENTRYPOINT = {
+  fn: Component,
+  params: [{}],
+};
+
+```
+
+## Code
+
+```javascript
+import { c as _c } from "react/compiler-runtime"; // @validateRefAccessDuringRender
+import { useRef } from "react";
+
+// Simulates react-hook-form's handleSubmit
+function handleSubmit(callback) {
+  const $ = _c(2);
+  let t0;
+  if ($[0] !== callback) {
+    t0 = (event) => {
+      event.preventDefault();
+      callback({} as T);
+    };
+    $[0] = callback;
+    $[1] = t0;
+  } else {
+    t0 = $[1];
+  }
+  return t0;
+}
+
+// Simulates an upload function
+async function upload(file) {
+  const $ = _c(1);
+  let t0;
+  if ($[0] === Symbol.for("react.memo_cache_sentinel")) {
+    t0 = { blob: { url: "https://example.com/file.jpg" } };
+    $[0] = t0;
+  } else {
+    t0 = $[0];
+  }
+  return t0;
+}
+
+interface SignatureRef {
+  toFile(): any;
+}
+
+function Component() {
+  const $ = _c(4);
+  const ref = useRef(null);
+
+  const onSubmit = async (value) => {
+    let sigUrl;
+    if (value.hasSignature) {
+      const { blob } = await upload(ref.current?.toFile());
+      sigUrl = blob?.url || "";
+    } else {
+      sigUrl = value.signature;
+    }
+
+    console.log("Signature URL:", sigUrl);
+  };
+
+  const t0 = handleSubmit(onSubmit);
+  let t1;
+  let t2;
+  if ($[0] === Symbol.for("react.memo_cache_sentinel")) {
+    t1 = <input type="text" name="signature" />;
+    t2 = <button type="submit">Submit</button>;
+    $[0] = t1;
+    $[1] = t2;
+  } else {
+    t1 = $[0];
+    t2 = $[1];
+  }
+  let t3;
+  if ($[2] !== t0) {
+    t3 = (
+      <form onSubmit={t0}>
+        {t1}
+        {t2}
+      </form>
+    );
+    $[2] = t0;
+    $[3] = t3;
+  } else {
+    t3 = $[3];
+  }
+  return t3;
+}
+
+export const FIXTURE_ENTRYPOINT = {
+  fn: Component,
+  params: [{}],
+};
+
+```
+      
+### Eval output
+(kind: ok) <form><input type="text" name="signature"><button type="submit">Submit</button></form>
\ No newline at end of file
diff --git a/compiler/packages/babel-plugin-react-compiler/src/__tests__/fixtures/compiler/allow-ref-access-in-async-event-handler-wrapper.tsx b/compiler/packages/babel-plugin-react-compiler/src/__tests__/fixtures/compiler/allow-ref-access-in-async-event-handler-wrapper.tsx
new file mode 100644
index 000000000000..dfb1f84961c8
--- /dev/null
+++ b/compiler/packages/babel-plugin-react-compiler/src/__tests__/fixtures/compiler/allow-ref-access-in-async-event-handler-wrapper.tsx
@@ -0,0 +1,48 @@
+// @validateRefAccessDuringRender
+import {useRef} from 'react';
+
+// Simulates react-hook-form's handleSubmit
+function handleSubmit<T>(callback: (data: T) => void | Promise<void>) {
+  return (event: any) => {
+    event.preventDefault();
+    callback({} as T);
+  };
+}
+
+// Simulates an upload function
+async function upload(file: any): Promise<{blob: {url: string}}> {
+  return {blob: {url: 'https://example.com/file.jpg'}};
+}
+
+interface SignatureRef {
+  toFile(): any;
+}
+
+function Component() {
+  const ref = useRef<SignatureRef>(null);
+
+  const onSubmit = async (value: any) => {
+    // This should be allowed: accessing ref.current in an async event handler
+    // that's wrapped and passed to onSubmit prop
+    let sigUrl: string;
+    if (value.hasSignature) {
+      const {blob} = await upload(ref.current?.toFile());
+      sigUrl = blob?.url || '';
+    } else {
+      sigUrl = value.signature;
+    }
+    console.log('Signature URL:', sigUrl);
+  };
+
+  return (
+    <form onSubmit={handleSubmit(onSubmit)}>
+      <input type="text" name="signature" />
+      <button type="submit">Submit</button>
+    </form>
+  );
+}
+
+export const FIXTURE_ENTRYPOINT = {
+  fn: Component,
+  params: [{}],
+};
diff --git a/compiler/packages/babel-plugin-react-compiler/src/__tests__/fixtures/compiler/allow-ref-access-in-event-handler-wrapper.expect.md b/compiler/packages/babel-plugin-react-compiler/src/__tests__/fixtures/compiler/allow-ref-access-in-event-handler-wrapper.expect.md
new file mode 100644
index 000000000000..805b31e92bf8
--- /dev/null
+++ b/compiler/packages/babel-plugin-react-compiler/src/__tests__/fixtures/compiler/allow-ref-access-in-event-handler-wrapper.expect.md
@@ -0,0 +1,101 @@
+
+## Input
+
+```javascript
+// @validateRefAccessDuringRender
+import {useRef} from 'react';
+
+// Simulates react-hook-form's handleSubmit or similar event handler wrappers
+function handleSubmit<T>(callback: (data: T) => void) {
+  return (event: any) => {
+    event.preventDefault();
+    callback({} as T);
+  };
+}
+
+function Component() {
+  const ref = useRef<HTMLInputElement>(null);
+
+  const onSubmit = (data: any) => {
+    // This should be allowed: accessing ref.current in an event handler
+    // that's wrapped by handleSubmit and passed to onSubmit prop
+    if (ref.current !== null) {
+      console.log(ref.current.value);
+    }
+  };
+
+  return (
+    <>
+      <input ref={ref} />
+      <form onSubmit={handleSubmit(onSubmit)}>
+        <button type="submit">Submit</button>
+      </form>
+    </>
+  );
+}
+
+export const FIXTURE_ENTRYPOINT = {
+  fn: Component,
+  params: [{}],
+};
+
+```
+
+## Code
+
+```javascript
+import { c as _c } from "react/compiler-runtime"; // @validateRefAccessDuringRender
+import { useRef } from "react";
+
+// Simulates react-hook-form's handleSubmit or similar event handler wrappers
+function handleSubmit(callback) {
+  const $ = _c(2);
+  let t0;
+  if ($[0] !== callback) {
+    t0 = (event) => {
+      event.preventDefault();
+      callback({} as T);
+    };
+    $[0] = callback;
+    $[1] = t0;
+  } else {
+    t0 = $[1];
+  }
+  return t0;
+}
+
+function Component() {
+  const $ = _c(1);
+  const ref = useRef(null);
+  let t0;
+  if ($[0] === Symbol.for("react.memo_cache_sentinel")) {
+    const onSubmit = (data) => {
+      if (ref.current !== null) {
+        console.log(ref.current.value);
+      }
+    };
+
+    t0 = (
+      <>
+        <input ref={ref} />
+        <form onSubmit={handleSubmit(onSubmit)}>
+          <button type="submit">Submit</button>
+        </form>
+      </>
+    );
+    $[0] = t0;
+  } else {
+    t0 = $[0];
+  }
+  return t0;
+}
+
+export const FIXTURE_ENTRYPOINT = {
+  fn: Component,
+  params: [{}],
+};
+
+```
+      
+### Eval output
+(kind: ok) <input><form><button type="submit">Submit</button></form>
\ No newline at end of file
diff --git a/compiler/packages/babel-plugin-react-compiler/src/__tests__/fixtures/compiler/allow-ref-access-in-event-handler-wrapper.tsx b/compiler/packages/babel-plugin-react-compiler/src/__tests__/fixtures/compiler/allow-ref-access-in-event-handler-wrapper.tsx
new file mode 100644
index 000000000000..59ee12e5c5a7
--- /dev/null
+++ b/compiler/packages/babel-plugin-react-compiler/src/__tests__/fixtures/compiler/allow-ref-access-in-event-handler-wrapper.tsx
@@ -0,0 +1,36 @@
+// @validateRefAccessDuringRender
+import {useRef} from 'react';
+
+// Simulates react-hook-form's handleSubmit or similar event handler wrappers
+function handleSubmit<T>(callback: (data: T) => void) {
+  return (event: any) => {
+    event.preventDefault();
+    callback({} as T);
+  };
+}
+
+function Component() {
+  const ref = useRef<HTMLInputElement>(null);
+
+  const onSubmit = (data: any) => {
+    // This should be allowed: accessing ref.current in an event handler
+    // that's wrapped by handleSubmit and passed to onSubmit prop
+    if (ref.current !== null) {
+      console.log(ref.current.value);
+    }
+  };
+
+  return (
+    <>
+      <input ref={ref} />
+      <form onSubmit={handleSubmit(onSubmit)}>
+        <button type="submit">Submit</button>
+      </form>
+    </>
+  );
+}
+
+export const FIXTURE_ENTRYPOINT = {
+  fn: Component,
+  params: [{}],
+};
diff --git a/compiler/packages/babel-plugin-react-compiler/src/__tests__/fixtures/compiler/error.ref-value-in-custom-component-event-handler-wrapper.expect.md b/compiler/packages/babel-plugin-react-compiler/src/__tests__/fixtures/compiler/error.ref-value-in-custom-component-event-handler-wrapper.expect.md
new file mode 100644
index 000000000000..97f6732f279e
--- /dev/null
+++ b/compiler/packages/babel-plugin-react-compiler/src/__tests__/fixtures/compiler/error.ref-value-in-custom-component-event-handler-wrapper.expect.md
@@ -0,0 +1,69 @@
+
+## Input
+
+```javascript
+// @validateRefAccessDuringRender
+import {useRef} from 'react';
+
+// Simulates a custom component wrapper
+function CustomForm({onSubmit, children}: any) {
+  return <form onSubmit={onSubmit}>{children}</form>;
+}
+
+// Simulates react-hook-form's handleSubmit
+function handleSubmit<T>(callback: (data: T) => void) {
+  return (event: any) => {
+    event.preventDefault();
+    callback({} as T);
+  };
+}
+
+function Component() {
+  const ref = useRef<HTMLInputElement>(null);
+
+  const onSubmit = (data: any) => {
+    // This should error: passing function with ref access to custom component
+    // event handler, even though it would be safe on a native <form>
+    if (ref.current !== null) {
+      console.log(ref.current.value);
+    }
+  };
+
+  return (
+    <>
+      <input ref={ref} />
+      <CustomForm onSubmit={handleSubmit(onSubmit)}>
+        <button type="submit">Submit</button>
+      </CustomForm>
+    </>
+  );
+}
+
+export const FIXTURE_ENTRYPOINT = {
+  fn: Component,
+  params: [{}],
+};
+
+```
+
+
+## Error
+
+```
+Found 1 error:
+
+Error: Cannot access refs during render
+
+React refs are values that are not needed for rendering. Refs should only be accessed outside of render, such as in event handlers or effects. Accessing a ref value (the `current` property) during render can cause your component not to update as expected (https://react.dev/reference/react/useRef).
+
+error.ref-value-in-custom-component-event-handler-wrapper.ts:31:41
+  29 |     <>
+  30 |       <input ref={ref} />
+> 31 |       <CustomForm onSubmit={handleSubmit(onSubmit)}>
+     |                                          ^^^^^^^^ Passing a ref to a function may read its value during render
+  32 |         <button type="submit">Submit</button>
+  33 |       </CustomForm>
+  34 |     </>
+```
+          
+      
\ No newline at end of file
diff --git a/compiler/packages/babel-plugin-react-compiler/src/__tests__/fixtures/compiler/error.ref-value-in-custom-component-event-handler-wrapper.tsx b/compiler/packages/babel-plugin-react-compiler/src/__tests__/fixtures/compiler/error.ref-value-in-custom-component-event-handler-wrapper.tsx
new file mode 100644
index 000000000000..467486ff7b3a
--- /dev/null
+++ b/compiler/packages/babel-plugin-react-compiler/src/__tests__/fixtures/compiler/error.ref-value-in-custom-component-event-handler-wrapper.tsx
@@ -0,0 +1,41 @@
+// @validateRefAccessDuringRender
+import {useRef} from 'react';
+
+// Simulates a custom component wrapper
+function CustomForm({onSubmit, children}: any) {
+  return <form onSubmit={onSubmit}>{children}</form>;
+}
+
+// Simulates react-hook-form's handleSubmit
+function handleSubmit<T>(callback: (data: T) => void) {
+  return (event: any) => {
+    event.preventDefault();
+    callback({} as T);
+  };
+}
+
+function Component() {
+  const ref = useRef<HTMLInputElement>(null);
+
+  const onSubmit = (data: any) => {
+    // This should error: passing function with ref access to custom component
+    // event handler, even though it would be safe on a native <form>
+    if (ref.current !== null) {
+      console.log(ref.current.value);
+    }
+  };
+
+  return (
+    <>
+      <input ref={ref} />
+      <CustomForm onSubmit={handleSubmit(onSubmit)}>
+        <button type="submit">Submit</button>
+      </CustomForm>
+    </>
+  );
+}
+
+export const FIXTURE_ENTRYPOINT = {
+  fn: Component,
+  params: [{}],
+};
diff --git a/compiler/packages/babel-plugin-react-compiler/src/__tests__/fixtures/compiler/error.ref-value-in-event-handler-wrapper.expect.md b/compiler/packages/babel-plugin-react-compiler/src/__tests__/fixtures/compiler/error.ref-value-in-event-handler-wrapper.expect.md
new file mode 100644
index 000000000000..41586dd744aa
--- /dev/null
+++ b/compiler/packages/babel-plugin-react-compiler/src/__tests__/fixtures/compiler/error.ref-value-in-event-handler-wrapper.expect.md
@@ -0,0 +1,55 @@
+
+## Input
+
+```javascript
+// @validateRefAccessDuringRender
+import {useRef} from 'react';
+
+// Simulates a handler wrapper
+function handleClick(value: any) {
+  return () => {
+    console.log(value);
+  };
+}
+
+function Component() {
+  const ref = useRef(null);
+
+  // This should still error: passing ref.current directly to a wrapper
+  // The ref value is accessed during render, not in the event handler
+  return (
+    <>
+      <input ref={ref} />
+      <button onClick={handleClick(ref.current)}>Click</button>
+    </>
+  );
+}
+
+export const FIXTURE_ENTRYPOINT = {
+  fn: Component,
+  params: [{}],
+};
+
+```
+
+
+## Error
+
+```
+Found 1 error:
+
+Error: Cannot access refs during render
+
+React refs are values that are not needed for rendering. Refs should only be accessed outside of render, such as in event handlers or effects. Accessing a ref value (the `current` property) during render can cause your component not to update as expected (https://react.dev/reference/react/useRef).
+
+error.ref-value-in-event-handler-wrapper.ts:19:35
+  17 |     <>
+  18 |       <input ref={ref} />
+> 19 |       <button onClick={handleClick(ref.current)}>Click</button>
+     |                                    ^^^^^^^^^^^ Cannot access ref value during render
+  20 |     </>
+  21 |   );
+  22 | }
+```
+          
+      
\ No newline at end of file
diff --git a/compiler/packages/babel-plugin-react-compiler/src/__tests__/fixtures/compiler/error.ref-value-in-event-handler-wrapper.tsx b/compiler/packages/babel-plugin-react-compiler/src/__tests__/fixtures/compiler/error.ref-value-in-event-handler-wrapper.tsx
new file mode 100644
index 000000000000..5002e910aceb
--- /dev/null
+++ b/compiler/packages/babel-plugin-react-compiler/src/__tests__/fixtures/compiler/error.ref-value-in-event-handler-wrapper.tsx
@@ -0,0 +1,27 @@
+// @validateRefAccessDuringRender
+import {useRef} from 'react';
+
+// Simulates a handler wrapper
+function handleClick(value: any) {
+  return () => {
+    console.log(value);
+  };
+}
+
+function Component() {
+  const ref = useRef(null);
+
+  // This should still error: passing ref.current directly to a wrapper
+  // The ref value is accessed during render, not in the event handler
+  return (
+    <>
+      <input ref={ref} />
+      <button onClick={handleClick(ref.current)}>Click</button>
+    </>
+  );
+}
+
+export const FIXTURE_ENTRYPOINT = {
+  fn: Component,
+  params: [{}],
+};
diff --git a/packages/react-debug-tools/src/__tests__/ReactHooksInspection-test.js b/packages/react-debug-tools/src/__tests__/ReactHooksInspection-test.js
index 18dab0710f25..c5024bf5d676 100644
--- a/packages/react-debug-tools/src/__tests__/ReactHooksInspection-test.js
+++ b/packages/react-debug-tools/src/__tests__/ReactHooksInspection-test.js
@@ -20,6 +20,10 @@ function normalizeSourceLoc(tree) {
       node.hookSource.lineNumber = 0;
       node.hookSource.columnNumber = 0;
     }
+    // Normalize Promise objects to hide internal symbols
+    if (node.value instanceof Promise) {
+      node.value = Object.create(Promise.prototype);
+    }
     normalizeSourceLoc(node.subHooks);
   });
   return tree;