diff --git a/CMake/ctkMacroWrapPythonQt.cmake b/CMake/ctkMacroWrapPythonQt.cmake
index d36d22e9a3..5239d1e743 100644
--- a/CMake/ctkMacroWrapPythonQt.cmake
+++ b/CMake/ctkMacroWrapPythonQt.cmake
@@ -215,12 +215,6 @@ macro(ctkMacroWrapPythonQt WRAPPING_NAMESPACE TARGET SRCS_LIST_NAME SOURCES IS_W
     endif()
   endforeach()
 
-  # PythonQtGenerator expects a colon ':' separated list
-  set(INCLUDE_DIRS_TO_WRAP)
-  foreach(include ${CTK_BASE_INCLUDE_DIRS})
-    set(INCLUDE_DIRS_TO_WRAP "${INCLUDE_DIRS_TO_WRAP}:${include}")
-  endforeach()
-
   # Prepare custom_command argument
   set(SOURCES_TO_WRAP_ARG)
   foreach(source ${SOURCES_TO_WRAP})
@@ -234,16 +228,6 @@ macro(ctkMacroWrapPythonQt WRAPPING_NAMESPACE TARGET SRCS_LIST_NAME SOURCES IS_W
   # Create intermediate output directory
   execute_process(COMMAND ${CMAKE_COMMAND} -E make_directory ${CMAKE_CURRENT_BINARY_DIR}/${wrap_int_dir})
 
-  # On Windows, to avoid "too long input" error, dump INCLUDE_DIRS_TO_WRAP into a file
-  if(WIN32)
-    # File containing the moc flags
-    set(include_dirs_to_wrap_filename includeDirsToWrap_${WRAPPING_NAMESPACE_UNDERSCORE}_${TARGET}.txt)
-    set(include_dirs_to_wrap_file ${CMAKE_CURRENT_BINARY_DIR}/${wrap_int_dir}${include_dirs_to_wrap_filename})
-    file(WRITE ${include_dirs_to_wrap_file} ${INCLUDE_DIRS_TO_WRAP})
-    # The arg passed to the custom command will be the file containing the list of include dirs to wrap
-    set(INCLUDE_DIRS_TO_WRAP ${include_dirs_to_wrap_file})
-  endif()
-
   set(wrapper_init_cpp_filename ${WRAPPING_NAMESPACE_UNDERSCORE}_${TARGET}_init.cpp)
   set(wrapper_init_cpp_file ${CMAKE_CURRENT_BINARY_DIR}/${wrap_int_dir}${wrapper_init_cpp_filename})
 
@@ -267,7 +251,6 @@ macro(ctkMacroWrapPythonQt WRAPPING_NAMESPACE TARGET SRCS_LIST_NAME SOURCES IS_W
       -DWRAPPING_NAMESPACE:STRING=${WRAPPING_NAMESPACE}
       -DTARGET:STRING=${TARGET}
       -DSOURCES:STRING=${SOURCES_TO_WRAP_ARG}
-      -DINCLUDE_DIRS:STRING=${INCLUDE_DIRS_TO_WRAP}
       -DOUTPUT_DIR:PATH=${CMAKE_CURRENT_BINARY_DIR}
       -DWRAP_INT_DIR:STRING=${wrap_int_dir}
       -DQT_QMAKE_EXECUTABLE:FILEPATH=${QT_QMAKE_EXECUTABLE}
diff --git a/CMake/ctkScriptWrapPythonQt_Light.cmake b/CMake/ctkScriptWrapPythonQt_Light.cmake
index 09c18bbd10..723e06892e 100644
--- a/CMake/ctkScriptWrapPythonQt_Light.cmake
+++ b/CMake/ctkScriptWrapPythonQt_Light.cmake
@@ -32,7 +32,7 @@
 # or from the command line using the following syntax:
 #
 #    cmake -DWRAPPING_NAMESPACE:STRING=org.commontk -DTARGET:STRING=MyLib
-#          -DSOURCES:STRING="file1^^file2" -DINCLUDE_DIRS:STRING=/path1:/path2
+#          -DSOURCES:STRING="file1^^file2"
 #          -DWRAP_INT_DIR:STRING=subir/subir/
 #          -DOUTPUT_DIR:PATH=/path  -DQT_QMAKE_EXECUTABLE:PATH=/path/to/qt/qmake
 #          -DPYTHON_EXECUTABLE:FILEPATH=/path/to/python
@@ -105,7 +105,7 @@ if(NOT DEFINED CMAKE_CURRENT_LIST_FILENAME)
 endif()
 
 # Check for non-defined var
-foreach(var WRAPPING_NAMESPACE TARGET SOURCES INCLUDE_DIRS WRAP_INT_DIR HAS_DECORATOR)
+foreach(var WRAPPING_NAMESPACE TARGET SOURCES WRAP_INT_DIR HAS_DECORATOR)
   if(NOT DEFINED ${var})
     message(FATAL_ERROR "${var} not specified when calling ctkScriptWrapPythonQt")
   endif()