diff --git a/.github/workflows/ci.yml b/.github/workflows/ci.yml
index b0c0aef4..d2cabe69 100644
--- a/.github/workflows/ci.yml
+++ b/.github/workflows/ci.yml
@@ -16,7 +16,7 @@ on:
 
 jobs:
   lint:
-    name: Lint and flake code
+    name: Lint and ruff code
     runs-on: ubuntu-latest
 
     steps:
diff --git a/.isort.cfg b/.isort.cfg
deleted file mode 100644
index abf82742..00000000
--- a/.isort.cfg
+++ /dev/null
@@ -1,5 +0,0 @@
-[settings]
-skip_glob=msgspec/__init__.py,examples/*
-multi_line_output=3
-include_trailing_comma=true
-combine_as_imports=true
diff --git a/.pre-commit-config.yaml b/.pre-commit-config.yaml
index 143d9533..fd24f180 100644
--- a/.pre-commit-config.yaml
+++ b/.pre-commit-config.yaml
@@ -1,8 +1,8 @@
 repos:
-  - repo: https://github.com/pycqa/isort
-    rev: 5.12.0
+  - repo: https://github.com/astral-sh/ruff-pre-commit
+    rev: v0.0.275
     hooks:
-      - id: isort
+      - id: ruff
         language_version: python3
 
   - repo: https://github.com/psf/black
@@ -11,12 +11,6 @@ repos:
       - id: black
         language_version: python3
 
-  - repo: https://github.com/pycqa/flake8
-    rev: 5.0.4
-    hooks:
-      - id: flake8
-        language_version: python3
-
   - repo: https://github.com/codespell-project/codespell
     rev: v2.2.2
     hooks:
diff --git a/pyproject.toml b/pyproject.toml
new file mode 100644
index 00000000..bf8e8153
--- /dev/null
+++ b/pyproject.toml
@@ -0,0 +1,25 @@
+[tool.ruff]
+exclude = [
+    "*.pyi",
+    "__init__.py",
+    "_version.py",
+    "versioneer.py",
+    "basic_typing_examples.py",
+    "json.py",
+    "msgpack.py",
+    "test_JSONTestSuite.py",
+    "conf.py",
+]
+ignore = [
+    "E721", # Comparing types instead of isinstance
+    "E741", # Ambiguous variable names
+]
+select = [
+    "E", # PEP8 Errors
+    "F", # Pyflakes
+    "W", # PEP8 Warnings
+]
+line-length = 100
+
+[tool.ruff.isort]
+combine-as-imports = true
diff --git a/setup.cfg b/setup.cfg
index 4a1cdacd..86465ce0 100644
--- a/setup.cfg
+++ b/setup.cfg
@@ -1,20 +1,3 @@
-[flake8]
-exclude =
-    __init__.py,
-    _version.py,
-    versioneer.py,
-    basic_typing_examples.py,
-    json.py,
-    msgpack.py,
-    test_JSONTestSuite.py,
-    conf.py
-ignore =
-    E721,  # Comparing types instead of isinstance
-    E741,  # Ambiguous variable names
-    W503,  # line break before binary operator
-    W504,  # line break after binary operator
-max-line-length = 100
-
 [codespell]
 skip=*.py,*.c,*.h