diff --git a/Containerfile b/Containerfile
index 8d3fc420f..8bdad9c6a 100644
--- a/Containerfile
+++ b/Containerfile
@@ -23,7 +23,7 @@ RUN microdnf -y --setopt=install_weak_deps=0 --setopt=tsflags=nodocs install \
     rpm-build \
     gcc gcc-c++ make cmake pkgconfig \
     cyrus-sasl-devel openssl-devel libuuid-devel \
-    python3-devel python3-setuptools python3-wheel python3-pip \
+    python3.11-devel python3.11-setuptools python3.11-wheel python3.11-pip \
     libnghttp2-devel \
     wget tar patch findutils git \
     libtool \
@@ -49,7 +49,7 @@ FROM registry.access.redhat.com/ubi9/ubi-minimal:latest
 RUN microdnf -y --setopt=install_weak_deps=0 --setopt=tsflags=nodocs install \
     glibc \
     cyrus-sasl-lib cyrus-sasl-plain cyrus-sasl-gssapi openssl \
-    python3 \
+    python3.11 \
     libnghttp2 \
     gettext hostname iputils \
     shadow-utils \
diff --git a/python/CMakeLists.txt b/python/CMakeLists.txt
index 14b248218..2defd7bad 100644
--- a/python/CMakeLists.txt
+++ b/python/CMakeLists.txt
@@ -32,20 +32,15 @@ add_custom_target(NAME ALL
 configure_file(${CMAKE_SOURCE_DIR}/python/skupper_router/_skupper_router_site.py.in
                ${CMAKE_CURRENT_BINARY_DIR}/_skupper_router_site.py)
 
-configure_file(${CMAKE_CURRENT_SOURCE_DIR}/setup.py ${CMAKE_CURRENT_BINARY_DIR}/setup.py COPYONLY)
-configure_file(${CMAKE_CURRENT_SOURCE_DIR}/setup.cfg.in ${CMAKE_CURRENT_BINARY_DIR}/setup.cfg)
+configure_file(${CMAKE_CURRENT_SOURCE_DIR}/pyproject.toml.in
+               ${CMAKE_CURRENT_BINARY_DIR}/pyproject.toml)
 
 # Use pip install to install the public python modules.
 # --compile option compiles Python source files to bytecode
 # --disable-pip-version-check is useful in offline scenarios to avoid a query to PyPI
-# --no-use-pep517 is necessary for compatibility with older setuptools on centos stream 8 and 9
-
-# --check-build-dependencies option cannot be used here since centos stream versions 8 and 9 don't support it
-# --no-build-isolation by itself would also skip PyPI downloads, but centos stream 8 and 9 have older setuptools which is buggy
-#                      see https://github.com/pypa/pip/issues/6264, https://github.com/pypa/setuptools/issues/3291
 install(CODE
         "execute_process( \
-        COMMAND ${Python_EXECUTABLE} -m pip install ${CMAKE_CURRENT_BINARY_DIR} --disable-pip-version-check --no-build-isolation --no-use-pep517 --ignore-installed --verbose --compile --prefix=\$ENV{DESTDIR}${CMAKE_INSTALL_PREFIX} \
+        COMMAND ${Python_EXECUTABLE} -m pip install ${CMAKE_CURRENT_BINARY_DIR} --disable-pip-version-check --no-build-isolation --ignore-installed --verbose --compile --prefix=\$ENV{DESTDIR}${CMAKE_INSTALL_PREFIX} \
         WORKING_DIRECTORY ${CMAKE_CURRENT_BINARY_DIR} \
         COMMAND_ECHO STDOUT \
         COMMAND_ERROR_IS_FATAL ANY)")
diff --git a/python/setup.py b/python/pyproject.toml.in
similarity index 53%
rename from python/setup.py
rename to python/pyproject.toml.in
index 9a2317654..aa328bfa3 100644
--- a/python/setup.py
+++ b/python/pyproject.toml.in
@@ -1,4 +1,3 @@
-#!/usr/bin/env python3
 #
 # Licensed to the Apache Software Foundation (ASF) under one
 # or more contributor license agreements.  See the NOTICE file
@@ -18,6 +17,30 @@
 # under the License.
 #
 
-from setuptools import setup
+[project]
+name="skupper_router"
+description = "Skupper Router tools and libraries"
+version = '${QPID_DISPATCH_VERSION}'
+authors = [
+    { name = "Skupper Project", email = "skupper@googlegroups.com" }
+]
+requires-python = ">=3.9"
 
-setup()
+[build-system]
+requires = ["setuptools", "wheel"]
+build-backend = "setuptools.build_meta"
+
+[tool.skupper_router]
+homepage = "https://skupper.io/"
+repository = "https://github.com/skupperproject/skupper-router/"
+
+[tool.setuptools]
+# By default, include-package-data is true in pyproject.toml, so you do
+# NOT have to specify this line.
+include-package-data = true
+
+[tool.setuptools.packages.find]
+where = ["src"]
+
+[tool.setuptools.package-data]
+"*" = ["*.json"]