diff --git a/docs/cluster.rst b/docs/cluster.rst
index 64c4288..9040bf8 100644
--- a/docs/cluster.rst
+++ b/docs/cluster.rst
@@ -22,6 +22,33 @@ Having 30 cores and 10GB of memory.
 
     snakemake --sdm conda --configfile config/config.yaml -c 30 --resources mem_mb=10000  --workflow-profile profiles/default
 
+Performance tweaks: Running specific rules with different resources
+~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
+
+Some of the rule swill benefit from multithreading or more memory. This can be specified within your profile, worflow profile or in the command line interface using :code:`--set-resources RULE_NAME:RESOURCE_NAME=VALUE` or :code:`---set-threads RULE_NAME=VALUE`. Before changing resources make sure that you really need the rule by running a dry run getting the list of executed rules only::code:`snakemamake -n --quiet rules`.
+
+Possible rules to tweaks:
+
+:Assignment:
+
+    :assignment_hybridFWRead_get_reads_by_cutadapt:
+        Only needed when using linker option in config. You can add more threads using :code:`--set-threads assignment_hybridFWRead_get_reads_by_cutadapt=4`. Default is always 1 thread.
+
+    :assignment_mapping_bbmap:
+        Only needed when using bbmap for mapping. Memory and threads can be optimized e.g. via :code:`--set-threads assignment_mapping_bbmap=30 --set-resources assignment_mapping_bbmap:mem_mb=10000`. Default is 1 thread and 4GB memory but we recommend to use 30 threads and 10GB if available.
+
+    :assignment_mapping_bwa:
+        Only needed when using bwa for mapping. Memory and threads can be optimized e.g. via :code:`--set-threads assignment_mapping_bwa=30 --set-resources assignment_mapping_bwa:mem_mb:10000`. Default is 1 thread but we recommend to use 30 threads and 10GB if available.
+
+    :assignment_collectBCs:
+        Threads can be optimized e.g. via :code:`--set-threads assignment_collectBCs=30`. Default is 1 thread but we recommend to use 30 threads if available.
+
+:Experiment:
+
+    :counts_onlyFW_raw_counts_by_cutadapt:
+        Only needed when you have only FW reads and use the adapter option. Threads can be optimized e.g. via :code:`--set-threads counts_onlyFW_raw_counts_by_cutadapt=30`. Default is 1 thread.
+
+
 Running on an HPC using SLURM
 -----------------------------
 
diff --git a/workflow/rules/assignment/hybridFWRead.smk b/workflow/rules/assignment/hybridFWRead.smk
index b20299e..a86048f 100644
--- a/workflow/rules/assignment/hybridFWRead.smk
+++ b/workflow/rules/assignment/hybridFWRead.smk
@@ -44,6 +44,7 @@ rule assignment_hybridFWRead_get_reads_by_cutadapt:
     """
     conda:
         "../../envs/cutadapt.yaml"
+    threads: 1
     input:
         lambda wc: config["assignments"][wc.assignment]["FW"],
     output:
@@ -55,6 +56,6 @@ rule assignment_hybridFWRead_get_reads_by_cutadapt:
         linker=lambda wc: config["assignments"][wc.assignment]["linker"],
     shell:
         """
-        cutadapt -a {params.linker} -G {params.linker}\
+        cutadapt --cores {threads} -a {params.linker} -G {params.linker}\
         -o {output.BC} -p {output.FW} <(zcat {input}) <(zcat {input}) &> {log}
         """
diff --git a/workflow/rules/assignment/mapping_bwa.smk b/workflow/rules/assignment/mapping_bwa.smk
index 9c8adaa..2bbfa5f 100644
--- a/workflow/rules/assignment/mapping_bwa.smk
+++ b/workflow/rules/assignment/mapping_bwa.smk
@@ -29,6 +29,7 @@ rule assignment_mapping_bwa:
     """
     conda:
         "../../envs/bwa_samtools_picard_htslib.yaml"
+    threads: 1
     input:
         reads="results/assignment/{assignment}/fastq/merge_split{split}.join.fastq.gz",
         reference="results/assignment/{assignment}/reference/reference.fa",
@@ -100,6 +101,7 @@ rule assignment_collect:
     """
     conda:
         "../../envs/bwa_samtools_picard_htslib.yaml"
+    threads: 1
     input:
         bams=lambda wc: expand(
             "results/assignment/{{assignment}}/{mapper}/merge_split{split}.mapped.bam",
diff --git a/workflow/rules/counts/counts_onlyFW.smk b/workflow/rules/counts/counts_onlyFW.smk
index b82136a..4dc0c7d 100644
--- a/workflow/rules/counts/counts_onlyFW.smk
+++ b/workflow/rules/counts/counts_onlyFW.smk
@@ -36,6 +36,7 @@ rule counts_onlyFW_raw_counts_by_cutadapt:
     """
     conda:
         "../../envs/cutadapt.yaml"
+    threads: 1
     input:
         lambda wc: getFW(wc.project, wc.condition, wc.replicate, wc.type),
     output:
@@ -49,7 +50,7 @@ rule counts_onlyFW_raw_counts_by_cutadapt:
     shell:
         """
         zcat {input} | \
-        cutadapt -a {params.adapter} - |
+        cutadapt --cores {threads} -a {params.adapter} - |
         awk 'NR%4==2 {{print $1}}' | \
         sort | \
         gzip -c > {output} 2> {log}