diff --git a/compiler-rt/lib/rtsan/rtsan_interceptors.cpp b/compiler-rt/lib/rtsan/rtsan_interceptors.cpp
index d186d1aaa8d93..9cc7214aef85c 100644
--- a/compiler-rt/lib/rtsan/rtsan_interceptors.cpp
+++ b/compiler-rt/lib/rtsan/rtsan_interceptors.cpp
@@ -64,13 +64,15 @@ INTERCEPTOR(int, open, const char *path, int oflag, ...) {
   // O_NONBLOCK
   __rtsan_notify_intercepted_call("open");
 
-  va_list args;
-  va_start(args, oflag);
-  const mode_t mode = va_arg(args, int);
-  va_end(args);
+  if (OpenReadsVaArgs(oflag)) {
+    va_list args;
+    va_start(args, oflag);
+    const mode_t mode = va_arg(args, int);
+    va_end(args);
+    return REAL(open)(path, oflag, mode);
+  }
 
-  const int result = REAL(open)(path, oflag, mode);
-  return result;
+  return REAL(open)(path, oflag);
 }
 
 #if SANITIZER_INTERCEPT_OPEN64
@@ -79,13 +81,15 @@ INTERCEPTOR(int, open64, const char *path, int oflag, ...) {
   // O_NONBLOCK
   __rtsan_notify_intercepted_call("open64");
 
-  va_list args;
-  va_start(args, oflag);
-  const mode_t mode = va_arg(args, int);
-  va_end(args);
+  if (OpenReadsVaArgs(oflag)) {
+    va_list args;
+    va_start(args, oflag);
+    const mode_t mode = va_arg(args, int);
+    va_end(args);
+    return REAL(open64)(path, oflag, mode);
+  }
 
-  const int result = REAL(open64)(path, oflag, mode);
-  return result;
+  return REAL(open64)(path, oflag);
 }
 #define RTSAN_MAYBE_INTERCEPT_OPEN64 INTERCEPT_FUNCTION(open64)
 #else
@@ -97,13 +101,15 @@ INTERCEPTOR(int, openat, int fd, const char *path, int oflag, ...) {
   // O_NONBLOCK
   __rtsan_notify_intercepted_call("openat");
 
-  va_list args;
-  va_start(args, oflag);
-  mode_t mode = va_arg(args, int);
-  va_end(args);
+  if (OpenReadsVaArgs(oflag)) {
+    va_list args;
+    va_start(args, oflag);
+    const mode_t mode = va_arg(args, int);
+    va_end(args);
+    return REAL(openat)(fd, path, oflag, mode);
+  }
 
-  const int result = REAL(openat)(fd, path, oflag, mode);
-  return result;
+  return REAL(openat)(fd, path, oflag);
 }
 
 #if SANITIZER_INTERCEPT_OPENAT64
@@ -112,13 +118,15 @@ INTERCEPTOR(int, openat64, int fd, const char *path, int oflag, ...) {
   // O_NONBLOCK
   __rtsan_notify_intercepted_call("openat64");
 
-  va_list args;
-  va_start(args, oflag);
-  mode_t mode = va_arg(args, int);
-  va_end(args);
+  if (OpenReadsVaArgs(oflag)) {
+    va_list args;
+    va_start(args, oflag);
+    const mode_t mode = va_arg(args, int);
+    va_end(args);
+    return REAL(openat64)(fd, path, oflag, mode);
+  }
 
-  const int result = REAL(openat64)(fd, path, oflag, mode);
-  return result;
+  return REAL(openat64)(fd, path, oflag);
 }
 #define RTSAN_MAYBE_INTERCEPT_OPENAT64 INTERCEPT_FUNCTION(openat64)
 #else
diff --git a/compiler-rt/lib/sanitizer_common/sanitizer_posix.cpp b/compiler-rt/lib/sanitizer_common/sanitizer_posix.cpp
index 7d7d575431994..69af6465a62c2 100644
--- a/compiler-rt/lib/sanitizer_common/sanitizer_posix.cpp
+++ b/compiler-rt/lib/sanitizer_common/sanitizer_posix.cpp
@@ -353,7 +353,15 @@ bool ShouldMockFailureToOpen(const char *path) {
          internal_strncmp(path, "/proc/", 6) == 0;
 }
 
-#if SANITIZER_LINUX && !SANITIZER_ANDROID && !SANITIZER_GO
+bool OpenReadsVaArgs(int oflag) {
+#  ifdef O_TMPFILE
+  return (oflag & (O_CREAT | O_TMPFILE)) != 0;
+#  else
+  return (oflag & O_CREAT) != 0;
+#  endif
+}
+
+#  if SANITIZER_LINUX && !SANITIZER_ANDROID && !SANITIZER_GO
 int GetNamedMappingFd(const char *name, uptr size, int *flags) {
   if (!common_flags()->decorate_proc_maps || !name)
     return -1;
diff --git a/compiler-rt/lib/sanitizer_common/sanitizer_posix.h b/compiler-rt/lib/sanitizer_common/sanitizer_posix.h
index d0954f77e9713..1f0795caa420c 100644
--- a/compiler-rt/lib/sanitizer_common/sanitizer_posix.h
+++ b/compiler-rt/lib/sanitizer_common/sanitizer_posix.h
@@ -108,6 +108,7 @@ bool IsStateDetached(int state);
 fd_t ReserveStandardFds(fd_t fd);
 
 bool ShouldMockFailureToOpen(const char *path);
+bool OpenReadsVaArgs(int oflag);
 
 // Create a non-file mapping with a given /proc/self/maps name.
 uptr MmapNamed(void *addr, uptr length, int prot, int flags, const char *name);
diff --git a/compiler-rt/lib/tsan/rtl/tsan_interceptors_posix.cpp b/compiler-rt/lib/tsan/rtl/tsan_interceptors_posix.cpp
index 53c876f4f9175..423d97e94d81a 100644
--- a/compiler-rt/lib/tsan/rtl/tsan_interceptors_posix.cpp
+++ b/compiler-rt/lib/tsan/rtl/tsan_interceptors_posix.cpp
@@ -1680,13 +1680,23 @@ TSAN_INTERCEPTOR(int, fstat64, int fd, void *buf) {
 #endif
 
 TSAN_INTERCEPTOR(int, open, const char *name, int oflag, ...) {
-  va_list ap;
-  va_start(ap, oflag);
-  mode_t mode = va_arg(ap, int);
-  va_end(ap);
+  mode_t mode = 0;
+  if (OpenReadsVaArgs(oflag)) {
+    va_list ap;
+    va_start(ap, oflag);
+    mode = va_arg(ap, int);
+    va_end(ap);
+  }
+
   SCOPED_TSAN_INTERCEPTOR(open, name, oflag, mode);
   READ_STRING(thr, pc, name, 0);
-  int fd = REAL(open)(name, oflag, mode);
+
+  int fd;
+  if (OpenReadsVaArgs(oflag))
+    fd = REAL(open)(name, oflag, mode);
+  else
+    fd = REAL(open)(name, oflag);
+
   if (fd >= 0)
     FdFileCreate(thr, pc, fd);
   return fd;