diff --git a/llvm/lib/Analysis/ValueTracking.cpp b/llvm/lib/Analysis/ValueTracking.cpp
index 4e79f41df2eb9..02a48d35a74aa 100644
--- a/llvm/lib/Analysis/ValueTracking.cpp
+++ b/llvm/lib/Analysis/ValueTracking.cpp
@@ -7777,6 +7777,8 @@ static bool isGuaranteedNotToBeUndefOrPoison(
       unsigned Num = PN->getNumIncomingValues();
       bool IsWellDefined = true;
       for (unsigned i = 0; i < Num; ++i) {
+        if (PN == PN->getIncomingValue(i))
+          continue;
         auto *TI = PN->getIncomingBlock(i)->getTerminator();
         if (!isGuaranteedNotToBeUndefOrPoison(PN->getIncomingValue(i), AC, TI,
                                               DT, Depth + 1, Kind)) {
diff --git a/llvm/test/Analysis/ValueTracking/phi-self.ll b/llvm/test/Analysis/ValueTracking/phi-self.ll
new file mode 100644
index 0000000000000..17afd872cab03
--- /dev/null
+++ b/llvm/test/Analysis/ValueTracking/phi-self.ll
@@ -0,0 +1,89 @@
+; NOTE: Assertions have been autogenerated by utils/update_test_checks.py UTC_ARGS: --version 5
+; RUN: opt -S -passes=instsimplify < %s | FileCheck %s
+
+; Test `%r` can be replaced by `%nonpoison`.
+
+define i32 @other_noundef(i32 noundef %arg) {
+; CHECK-LABEL: define i32 @other_noundef(
+; CHECK-SAME: i32 noundef [[ARG:%.*]]) {
+; CHECK-NEXT:  [[START:.*]]:
+; CHECK-NEXT:    br label %[[LOOP:.*]]
+; CHECK:       [[LOOP]]:
+; CHECK-NEXT:    [[NONPOISON:%.*]] = phi i32 [ 0, %[[START]] ], [ [[NONPOISON]], %[[BB0:.*]] ], [ [[ARG]], %[[BB1:.*]] ]
+; CHECK-NEXT:    [[I:%.*]] = call i32 @opaque()
+; CHECK-NEXT:    switch i32 [[I]], label %[[EXIT:.*]] [
+; CHECK-NEXT:      i32 0, label %[[BB0]]
+; CHECK-NEXT:      i32 1, label %[[BB1]]
+; CHECK-NEXT:    ]
+; CHECK:       [[EXIT]]:
+; CHECK-NEXT:    ret i32 [[NONPOISON]]
+; CHECK:       [[BB0]]:
+; CHECK-NEXT:    br label %[[LOOP]]
+; CHECK:       [[BB1]]:
+; CHECK-NEXT:    br label %[[LOOP]]
+;
+start:
+  br label %loop
+
+loop:
+  %nonpoison = phi i32 [ 0, %start ], [ %nonpoison, %bb0 ], [ %arg, %bb1 ]
+  %i = call i32 @opaque()
+  switch i32 %i, label %exit [
+  i32 0, label %bb0
+  i32 1, label %bb1
+  ]
+
+exit:
+  %r = freeze i32 %nonpoison
+  ret i32 %r
+
+bb0:
+  br label %loop
+
+bb1:
+  br label %loop
+}
+
+define i32 @other_poison(i32 %arg) {
+; CHECK-LABEL: define i32 @other_poison(
+; CHECK-SAME: i32 [[ARG:%.*]]) {
+; CHECK-NEXT:  [[START:.*]]:
+; CHECK-NEXT:    br label %[[LOOP:.*]]
+; CHECK:       [[LOOP]]:
+; CHECK-NEXT:    [[MAYPOISON:%.*]] = phi i32 [ 0, %[[START]] ], [ [[MAYPOISON]], %[[BB0:.*]] ], [ [[ARG]], %[[BB1:.*]] ]
+; CHECK-NEXT:    [[I:%.*]] = call i32 @opaque()
+; CHECK-NEXT:    switch i32 [[I]], label %[[EXIT:.*]] [
+; CHECK-NEXT:      i32 0, label %[[BB0]]
+; CHECK-NEXT:      i32 1, label %[[BB1]]
+; CHECK-NEXT:    ]
+; CHECK:       [[EXIT]]:
+; CHECK-NEXT:    [[R:%.*]] = freeze i32 [[MAYPOISON]]
+; CHECK-NEXT:    ret i32 [[R]]
+; CHECK:       [[BB0]]:
+; CHECK-NEXT:    br label %[[LOOP]]
+; CHECK:       [[BB1]]:
+; CHECK-NEXT:    br label %[[LOOP]]
+;
+start:
+  br label %loop
+
+loop:
+  %maypoison = phi i32 [ 0, %start ], [ %maypoison, %bb0 ], [ %arg, %bb1 ]
+  %i = call i32 @opaque()
+  switch i32 %i, label %exit [
+  i32 0, label %bb0
+  i32 1, label %bb1
+  ]
+
+exit:
+  %r = freeze i32 %maypoison
+  ret i32 %r
+
+bb0:
+  br label %loop
+
+bb1:
+  br label %loop
+}
+
+declare i32 @opaque()