diff --git a/clang/include/clang/CIR/Dialect/IR/CIROps.td b/clang/include/clang/CIR/Dialect/IR/CIROps.td
index bb394440bf8d8..e1be08c1bbbbd 100644
--- a/clang/include/clang/CIR/Dialect/IR/CIROps.td
+++ b/clang/include/clang/CIR/Dialect/IR/CIROps.td
@@ -683,8 +683,8 @@ def CIR_ConditionOp : CIR_Op<"condition", [
 //===----------------------------------------------------------------------===//
 
 defvar CIR_YieldableScopes = [
-  "ArrayCtor", "ArrayDtor", "CaseOp", "DoWhileOp", "ForOp", "IfOp", "ScopeOp",
-  "SwitchOp", "TernaryOp", "WhileOp"
+  "ArrayCtor", "ArrayDtor", "CaseOp", "DoWhileOp", "ForOp", "GlobalOp", "IfOp",
+  "ScopeOp", "SwitchOp", "TernaryOp", "WhileOp"
 ];
 
 def CIR_YieldOp : CIR_Op<"yield", [
@@ -1776,7 +1776,9 @@ def CIR_GlobalLinkageKind : CIR_I32EnumAttr<
 // is upstreamed.
 
 def CIR_GlobalOp : CIR_Op<"global", [
-  DeclareOpInterfaceMethods<CIRGlobalValueInterface>
+  DeclareOpInterfaceMethods<RegionBranchOpInterface>,
+  DeclareOpInterfaceMethods<CIRGlobalValueInterface>,
+  NoRegionArguments
 ]> {
   let summary = "Declare or define a global variable";
   let description = [{
@@ -1807,6 +1809,9 @@ def CIR_GlobalOp : CIR_Op<"global", [
                        UnitAttr:$dso_local,
                        OptionalAttr<I64Attr>:$alignment);
 
+  let regions = (region MaxSizedRegion<1>:$ctorRegion,
+                        MaxSizedRegion<1>:$dtorRegion);
+
   let assemblyFormat = [{
     ($sym_visibility^)?
     (`` $global_visibility^)?
@@ -1815,24 +1820,34 @@ def CIR_GlobalOp : CIR_Op<"global", [
     (`comdat` $comdat^)?
     (`dso_local` $dso_local^)?
     $sym_name
-    custom<GlobalOpTypeAndInitialValue>($sym_type, $initial_value)
+    custom<GlobalOpTypeAndInitialValue>($sym_type, $initial_value,
+                                        $ctorRegion, $dtorRegion)
     attr-dict
   }];
 
   let extraClassDeclaration = [{
-    bool isDeclaration() { return !getInitialValue(); }
+    bool isDeclaration() {
+      return !getInitialValue() && getCtorRegion().empty() && getDtorRegion().empty();
+    }
     bool hasInitializer() { return !isDeclaration(); }
   }];
 
   let skipDefaultBuilders = 1;
 
-  let builders = [OpBuilder<(ins
-    "llvm::StringRef":$sym_name,
-    "mlir::Type":$sym_type,
-    CArg<"bool", "false">:$isConstant,
-    // CIR defaults to external linkage.
-    CArg<"cir::GlobalLinkageKind",
-    "cir::GlobalLinkageKind::ExternalLinkage">:$linkage)>];
+  let builders = [
+    OpBuilder<(ins
+      "llvm::StringRef":$sym_name,
+      "mlir::Type":$sym_type,
+      CArg<"bool", "false">:$isConstant,
+      // CIR defaults to external linkage.
+      CArg<"cir::GlobalLinkageKind",
+           "cir::GlobalLinkageKind::ExternalLinkage">:$linkage,
+      CArg<"llvm::function_ref<void(mlir::OpBuilder &, mlir::Location)>",
+           "nullptr">:$ctorBuilder,
+      CArg<"llvm::function_ref<void(mlir::OpBuilder &, mlir::Location)>",
+           "nullptr">:$dtorBuilder)
+    >
+  ];
 
   let hasVerifier = 1;
 
diff --git a/clang/lib/CIR/Dialect/IR/CIRDialect.cpp b/clang/lib/CIR/Dialect/IR/CIRDialect.cpp
index 58ef500446aa7..fb87036fdfe21 100644
--- a/clang/lib/CIR/Dialect/IR/CIRDialect.cpp
+++ b/clang/lib/CIR/Dialect/IR/CIRDialect.cpp
@@ -1355,9 +1355,11 @@ mlir::LogicalResult cir::GlobalOp::verify() {
   return success();
 }
 
-void cir::GlobalOp::build(OpBuilder &odsBuilder, OperationState &odsState,
-                          llvm::StringRef sym_name, mlir::Type sym_type,
-                          bool isConstant, cir::GlobalLinkageKind linkage) {
+void cir::GlobalOp::build(
+    OpBuilder &odsBuilder, OperationState &odsState, llvm::StringRef sym_name,
+    mlir::Type sym_type, bool isConstant, cir::GlobalLinkageKind linkage,
+    function_ref<void(OpBuilder &, Location)> ctorBuilder,
+    function_ref<void(OpBuilder &, Location)> dtorBuilder) {
   odsState.addAttribute(getSymNameAttrName(odsState.name),
                         odsBuilder.getStringAttr(sym_name));
   odsState.addAttribute(getSymTypeAttrName(odsState.name),
@@ -1370,26 +1372,88 @@ void cir::GlobalOp::build(OpBuilder &odsBuilder, OperationState &odsState,
       cir::GlobalLinkageKindAttr::get(odsBuilder.getContext(), linkage);
   odsState.addAttribute(getLinkageAttrName(odsState.name), linkageAttr);
 
+  Region *ctorRegion = odsState.addRegion();
+  if (ctorBuilder) {
+    odsBuilder.createBlock(ctorRegion);
+    ctorBuilder(odsBuilder, odsState.location);
+  }
+
+  Region *dtorRegion = odsState.addRegion();
+  if (dtorBuilder) {
+    odsBuilder.createBlock(dtorRegion);
+    dtorBuilder(odsBuilder, odsState.location);
+  }
+
   odsState.addAttribute(getGlobalVisibilityAttrName(odsState.name),
                         cir::VisibilityAttr::get(odsBuilder.getContext()));
 }
 
+/// Given the region at `index`, or the parent operation if `index` is None,
+/// return the successor regions. These are the regions that may be selected
+/// during the flow of control. `operands` is a set of optional attributes that
+/// correspond to a constant value for each operand, or null if that operand is
+/// not a constant.
+void cir::GlobalOp::getSuccessorRegions(
+    mlir::RegionBranchPoint point, SmallVectorImpl<RegionSuccessor> &regions) {
+  // The `ctor` and `dtor` regions always branch back to the parent operation.
+  if (!point.isParent()) {
+    regions.push_back(RegionSuccessor());
+    return;
+  }
+
+  // Don't consider the ctor region if it is empty.
+  Region *ctorRegion = &this->getCtorRegion();
+  if (ctorRegion->empty())
+    ctorRegion = nullptr;
+
+  // Don't consider the dtor region if it is empty.
+  Region *dtorRegion = &this->getCtorRegion();
+  if (dtorRegion->empty())
+    dtorRegion = nullptr;
+
+  // If the condition isn't constant, both regions may be executed.
+  if (ctorRegion)
+    regions.push_back(RegionSuccessor(ctorRegion));
+  if (dtorRegion)
+    regions.push_back(RegionSuccessor(dtorRegion));
+}
+
 static void printGlobalOpTypeAndInitialValue(OpAsmPrinter &p, cir::GlobalOp op,
-                                             TypeAttr type,
-                                             Attribute initAttr) {
+                                             TypeAttr type, Attribute initAttr,
+                                             mlir::Region &ctorRegion,
+                                             mlir::Region &dtorRegion) {
+  auto printType = [&]() { p << ": " << type; };
   if (!op.isDeclaration()) {
     p << "= ";
-    // This also prints the type...
-    if (initAttr)
-      printConstant(p, initAttr);
+    if (!ctorRegion.empty()) {
+      p << "ctor ";
+      printType();
+      p << " ";
+      p.printRegion(ctorRegion,
+                    /*printEntryBlockArgs=*/false,
+                    /*printBlockTerminators=*/false);
+    } else {
+      // This also prints the type...
+      if (initAttr)
+        printConstant(p, initAttr);
+    }
+
+    if (!dtorRegion.empty()) {
+      p << " dtor ";
+      p.printRegion(dtorRegion,
+                    /*printEntryBlockArgs=*/false,
+                    /*printBlockTerminators=*/false);
+    }
   } else {
-    p << ": " << type;
+    printType();
   }
 }
 
-static ParseResult
-parseGlobalOpTypeAndInitialValue(OpAsmParser &parser, TypeAttr &typeAttr,
-                                 Attribute &initialValueAttr) {
+static ParseResult parseGlobalOpTypeAndInitialValue(OpAsmParser &parser,
+                                                    TypeAttr &typeAttr,
+                                                    Attribute &initialValueAttr,
+                                                    mlir::Region &ctorRegion,
+                                                    mlir::Region &dtorRegion) {
   mlir::Type opTy;
   if (parser.parseOptionalEqual().failed()) {
     // Absence of equal means a declaration, so we need to parse the type.
@@ -1397,16 +1461,38 @@ parseGlobalOpTypeAndInitialValue(OpAsmParser &parser, TypeAttr &typeAttr,
     if (parser.parseColonType(opTy))
       return failure();
   } else {
-    // Parse constant with initializer, examples:
-    //  cir.global @y = #cir.fp<1.250000e+00> : !cir.double
-    //  cir.global @rgb = #cir.const_array<[...] : !cir.array<i8 x 3>>
-    if (parseConstantValue(parser, initialValueAttr).failed())
-      return failure();
+    // Parse contructor, example:
+    //  cir.global @rgb = ctor : type { ... }
+    if (!parser.parseOptionalKeyword("ctor")) {
+      if (parser.parseColonType(opTy))
+        return failure();
+      auto parseLoc = parser.getCurrentLocation();
+      if (parser.parseRegion(ctorRegion, /*arguments=*/{}, /*argTypes=*/{}))
+        return failure();
+      if (ensureRegionTerm(parser, ctorRegion, parseLoc).failed())
+        return failure();
+    } else {
+      // Parse constant with initializer, examples:
+      //  cir.global @y = 3.400000e+00 : f32
+      //  cir.global @rgb = #cir.const_array<[...] : !cir.array<i8 x 3>>
+      if (parseConstantValue(parser, initialValueAttr).failed())
+        return failure();
+
+      assert(mlir::isa<mlir::TypedAttr>(initialValueAttr) &&
+             "Non-typed attrs shouldn't appear here.");
+      auto typedAttr = mlir::cast<mlir::TypedAttr>(initialValueAttr);
+      opTy = typedAttr.getType();
+    }
 
-    assert(mlir::isa<mlir::TypedAttr>(initialValueAttr) &&
-           "Non-typed attrs shouldn't appear here.");
-    auto typedAttr = mlir::cast<mlir::TypedAttr>(initialValueAttr);
-    opTy = typedAttr.getType();
+    // Parse destructor, example:
+    //   dtor { ... }
+    if (!parser.parseOptionalKeyword("dtor")) {
+      auto parseLoc = parser.getCurrentLocation();
+      if (parser.parseRegion(dtorRegion, /*arguments=*/{}, /*argTypes=*/{}))
+        return failure();
+      if (ensureRegionTerm(parser, dtorRegion, parseLoc).failed())
+        return failure();
+    }
   }
 
   typeAttr = TypeAttr::get(opTy);
diff --git a/clang/test/CIR/IR/global-init.cir b/clang/test/CIR/IR/global-init.cir
new file mode 100644
index 0000000000000..727c067e25472
--- /dev/null
+++ b/clang/test/CIR/IR/global-init.cir
@@ -0,0 +1,48 @@
+// RUN: cir-opt --verify-roundtrip %s -o - | FileCheck %s
+
+!u8i = !cir.int<u, 8>
+
+!rec_NeedsCtor = !cir.record<struct "NeedsCtor" padded {!u8i}>
+!rec_NeedsDtor = !cir.record<struct "NeedsDtor" padded {!u8i}>
+!rec_NeedsCtorDtor = !cir.record<struct "NeedsCtorDtor" padded {!u8i}>
+
+module attributes {cir.triple = "x86_64-unknown-linux-gnu"} {
+  cir.func private @_ZN9NeedsCtorC1Ev(!cir.ptr<!rec_NeedsCtor>)
+  cir.global external @needsCtor = ctor : !rec_NeedsCtor {
+    %0 = cir.get_global @needsCtor : !cir.ptr<!rec_NeedsCtor>
+    cir.call @_ZN9NeedsCtorC1Ev(%0) : (!cir.ptr<!rec_NeedsCtor>) -> ()
+  }
+  // CHECK: cir.global external @needsCtor = ctor : !rec_NeedsCtor {
+  // CHECK:   %0 = cir.get_global @needsCtor : !cir.ptr<!rec_NeedsCtor>
+  // CHECK:   cir.call @_ZN9NeedsCtorC1Ev(%0) : (!cir.ptr<!rec_NeedsCtor>) -> ()
+  // CHECK: }
+
+  cir.func private @_ZN9NeedsDtorD1Ev(!cir.ptr<!rec_NeedsDtor>)
+  cir.global external dso_local @needsDtor = #cir.zero : !rec_NeedsDtor dtor {
+    %0 = cir.get_global @needsDtor : !cir.ptr<!rec_NeedsDtor>
+    cir.call @_ZN9NeedsDtorD1Ev(%0) : (!cir.ptr<!rec_NeedsDtor>) -> ()
+  }
+  // CHECK: cir.global external dso_local @needsDtor = #cir.zero : !rec_NeedsDtor dtor {
+  // CHECK:   %0 = cir.get_global @needsDtor : !cir.ptr<!rec_NeedsDtor>
+  // CHECK:   cir.call @_ZN9NeedsDtorD1Ev(%0) : (!cir.ptr<!rec_NeedsDtor>) -> ()
+  // CHECK: }
+
+  cir.func private @_ZN13NeedsCtorDtorC1Ev(!cir.ptr<!rec_NeedsCtorDtor>)
+  cir.func private @_ZN13NeedsCtorDtorD1Ev(!cir.ptr<!rec_NeedsCtorDtor>)
+  cir.global external dso_local @needsCtorDtor = ctor : !rec_NeedsCtorDtor {
+    %0 = cir.get_global @needsCtorDtor : !cir.ptr<!rec_NeedsCtorDtor>
+    cir.call @_ZN13NeedsCtorDtorC1Ev(%0) : (!cir.ptr<!rec_NeedsCtorDtor>) -> ()
+  } dtor {
+    %0 = cir.get_global @needsCtorDtor : !cir.ptr<!rec_NeedsCtorDtor>
+    cir.call @_ZN13NeedsCtorDtorD1Ev(%0) : (!cir.ptr<!rec_NeedsCtorDtor>) -> ()
+  }
+  // CHECK: cir.func private @_ZN13NeedsCtorDtorC1Ev(!cir.ptr<!rec_NeedsCtorDtor>)
+  // CHECK: cir.func private @_ZN13NeedsCtorDtorD1Ev(!cir.ptr<!rec_NeedsCtorDtor>)
+  // CHECK: cir.global external dso_local @needsCtorDtor = ctor : !rec_NeedsCtorDtor {
+  // CHECK:   %0 = cir.get_global @needsCtorDtor : !cir.ptr<!rec_NeedsCtorDtor>
+  // CHECK:   cir.call @_ZN13NeedsCtorDtorC1Ev(%0) : (!cir.ptr<!rec_NeedsCtorDtor>) -> ()
+  // CHECK: } dtor {
+  // CHECK:   %0 = cir.get_global @needsCtorDtor : !cir.ptr<!rec_NeedsCtorDtor>
+  // CHECK:   cir.call @_ZN13NeedsCtorDtorD1Ev(%0) : (!cir.ptr<!rec_NeedsCtorDtor>) -> ()
+  // CHECK: }
+}