diff --git a/src/css/lightbox.css b/src/css/lightbox.css
index 99a025f0..b3b0beb3 100644
--- a/src/css/lightbox.css
+++ b/src/css/lightbox.css
@@ -21,6 +21,7 @@ body.lb-disable-scrolling {
   text-align: center;
   line-height: 0;
   font-weight: normal;
+  outline: none;
 }
 
 .lightbox .lb-image {
diff --git a/src/js/lightbox.js b/src/js/lightbox.js
index 897d415e..8f8ccfb0 100644
--- a/src/js/lightbox.js
+++ b/src/js/lightbox.js
@@ -99,7 +99,19 @@
     }
 
     var self = this;
-    $('<div id="lightboxOverlay" class="lightboxOverlay"></div><div id="lightbox" class="lightbox"><div class="lb-outerContainer"><div class="lb-container"><img class="lb-image" src="data:image/gif;base64,R0lGODlhAQABAIAAAP///wAAACH5BAEAAAAALAAAAAABAAEAAAICRAEAOw==" alt=""/><div class="lb-nav"><a class="lb-prev" aria-label="Previous image" href="" ></a><a class="lb-next" aria-label="Next image" href="" ></a></div><div class="lb-loader"><a class="lb-cancel"></a></div></div></div><div class="lb-dataContainer"><div class="lb-data"><div class="lb-details"><span class="lb-caption"></span><span class="lb-number"></span></div><div class="lb-closeContainer"><a class="lb-close"></a></div></div></div></div>').appendTo($('body'));
+
+    // The two root notes generated, #lightboxOverlay and #lightbox are given
+    // tabindex attrs so they are focusable. We attach our keyboard event
+    // listeners to these two elements, and not the document. Clicking anywhere
+    // while Lightbox is opened will keep the focus on or inside one of these
+    // two elements.
+    //
+    // We do this so we can prevent propogation of the Esc keypress when
+    // Lightbox is open. This prevents it from intefering with other components
+    // on the page below.
+    //
+    // Github issue: https://github.com/lokesh/lightbox2/issues/663
+    $('<div id="lightboxOverlay" tabindex="-1" class="lightboxOverlay"></div><div id="lightbox" tabindex="-1" class="lightbox"><div class="lb-outerContainer"><div class="lb-container"><img class="lb-image" src="data:image/gif;base64,R0lGODlhAQABAIAAAP///wAAACH5BAEAAAAALAAAAAABAAEAAAICRAEAOw==" alt=""/><div class="lb-nav"><a class="lb-prev" aria-label="Previous image" href="" ></a><a class="lb-next" aria-label="Next image" href="" ></a></div><div class="lb-loader"><a class="lb-cancel"></a></div></div></div><div class="lb-dataContainer"><div class="lb-data"><div class="lb-details"><span class="lb-caption"></span><span class="lb-number"></span></div><div class="lb-closeContainer"><a class="lb-close"></a></div></div></div></div>').appendTo($('body'));
 
     // Cache jQuery objects
     this.$lightbox       = $('#lightbox');
@@ -387,6 +399,10 @@
       self.$lightbox.find('.lb-dataContainer').width(newWidth);
       self.$lightbox.find('.lb-prevLink').height(newHeight);
       self.$lightbox.find('.lb-nextLink').height(newHeight);
+
+      // Set focus on one of the two root nodes so keyboard events are captured.
+      self.$overlay.focus();
+
       self.showImage();
     }
 
@@ -493,11 +509,13 @@
   };
 
   Lightbox.prototype.enableKeyboardNav = function() {
-    $(document).on('keyup.keyboard', $.proxy(this.keyboardAction, this));
+    this.$lightbox.on('keyup.keyboard', $.proxy(this.keyboardAction, this));
+    this.$overlay.on('keyup.keyboard', $.proxy(this.keyboardAction, this));
   };
 
   Lightbox.prototype.disableKeyboardNav = function() {
-    $(document).off('.keyboard');
+    this.$lightbox.off('.keyboard');
+    this.$overlay.off('.keyboard');
   };
 
   Lightbox.prototype.keyboardAction = function(event) {
@@ -507,6 +525,8 @@
 
     var keycode = event.keyCode;
     if (keycode === KEYCODE_ESC) {
+      // Prevent bubbling so as to not affect other components on the page.
+      event.stopPropagation();
       this.end();
     } else if (keycode === KEYCODE_LEFTARROW) {
       if (this.currentImageIndex !== 0) {