diff --git a/Dockerfile b/Dockerfile
index 496db5d..2668d25 100644
--- a/Dockerfile
+++ b/Dockerfile
@@ -7,22 +7,18 @@ FROM python:3.12-alpine AS builder
 RUN apk update --no-cache && apk add --no-cache build-base bash cmake git
 
 # Build mafft from source
-# mafft creates an entire directory, that's what we copy later and that's why it needs
-# to be added to the path
-RUN wget https://mafft.cbrc.jp/alignment/software/mafft-7.525-without-extensions-src.tgz
-RUN tar -xzf mafft-7.525-without-extensions-src.tgz
-RUN cd mafft-7.525-without-extensions/core && \
+RUN git clone https://gitlab.com/manulera/mafft.git
+RUN cd mafft && git checkout 3cf6cfa8b81756b27eed28ed368474b9ee50e2da
+RUN cd mafft/core && \
     sed -i 's/^PREFIX = .*/PREFIX = \/usr\/local\/bin\/mafft/' Makefile && \
     make && \
     make install
 
 # Build MARS from source
-RUN wget https://github.com/manulera/MARS/archive/refs/tags/v0.2.3.tar.gz && \
-tar -xzf v0.2.3.tar.gz && \
-cd MARS-0.2.3 && \
+RUN wget https://github.com/manulera/MARS/archive/refs/tags/v0.2.6.tar.gz && \
+tar -xzf v0.2.6.tar.gz && \
+cd MARS-0.2.6 && \
 ./pre-install.sh && \
-# Fix https://github.com/lorrainea/MARS/issues/20
-sed -i '/template <size_t PAGESIZE>/i\ #ifdef PAGESIZE\n#undef PAGESIZE\n#endif' ./seqan/file/file_page.h && \
 make -f Makefile && \
 mv mars /usr/local/bin/mars
 
diff --git a/poetry.lock b/poetry.lock
index 079f741..53958bb 100644
--- a/poetry.lock
+++ b/poetry.lock
@@ -1,4 +1,4 @@
-# This file is automatically @generated by Poetry 2.2.1 and should not be changed by hand.
+# This file is automatically @generated by Poetry 2.1.3 and should not be changed by hand.
 
 [[package]]
 name = "annotated-doc"
@@ -1431,33 +1431,19 @@ description = "Simple primer design and analysis"
 optional = false
 python-versions = ">=3.8"
 groups = ["main"]
-files = [
-    {file = "primer3_py-2.2.0-cp310-cp310-macosx_10_14_x86_64.whl", hash = "sha256:6eac54399aa03f5238964a6d82520018cd5e5ace4afdc778138f8a338b7be825"},
-    {file = "primer3_py-2.2.0-cp310-cp310-manylinux_2_17_x86_64.manylinux2014_x86_64.whl", hash = "sha256:90db12e7a22c00db7b79d9dcd33e031e0c6339d54d848f584d739658e029a80b"},
-    {file = "primer3_py-2.2.0-cp310-cp310-win_amd64.whl", hash = "sha256:f631b02273c17366d6f67fc34352259cf74963bbc04df7670734569c537d0dee"},
-    {file = "primer3_py-2.2.0-cp311-cp311-macosx_10_14_x86_64.whl", hash = "sha256:acd46659275b1e34298611f9f647d5a4c08812abf2beface2d4f88e77e604e38"},
-    {file = "primer3_py-2.2.0-cp311-cp311-manylinux_2_17_x86_64.manylinux2014_x86_64.whl", hash = "sha256:ebe237f5ca451d336ce2a9b7e35619e031264085a2e793c20e4dca3261b1e288"},
-    {file = "primer3_py-2.2.0-cp311-cp311-win_amd64.whl", hash = "sha256:b25d928971c9d6b04722723da0ac96a053ea3ab8470634b7de6ef3307c12b185"},
-    {file = "primer3_py-2.2.0-cp312-cp312-macosx_10_14_x86_64.whl", hash = "sha256:e9a0b1d51683c9cb03b59b3c905569935ce8d820a6d04fec64a7bb90cad203cb"},
-    {file = "primer3_py-2.2.0-cp312-cp312-manylinux_2_17_x86_64.manylinux2014_x86_64.whl", hash = "sha256:52cbc454d0551d7040820373cdf3b7471cdad4a3eccf84ee4e5d04635a72ab5f"},
-    {file = "primer3_py-2.2.0-cp312-cp312-win_amd64.whl", hash = "sha256:9464dd0253d2be7bd3955191615d0975f463d64ba0c32793873cf378642ee311"},
-    {file = "primer3_py-2.2.0-cp313-cp313-macosx_10_14_x86_64.whl", hash = "sha256:75fa4af6127ce33b48221a7376aeb0e4460b3ac20d275e3b44d245b07d7134e3"},
-    {file = "primer3_py-2.2.0-cp313-cp313-manylinux_2_17_x86_64.manylinux2014_x86_64.whl", hash = "sha256:a8868054236f301ed46d1f420ca5de650f0c3ddd1ed49dc92681b1eb85a46137"},
-    {file = "primer3_py-2.2.0-cp313-cp313-win_amd64.whl", hash = "sha256:7fd1d10e38f01c2ce61da5460807cb9fde53ce3c4c65d6aed10e34e88d178dc6"},
-    {file = "primer3_py-2.2.0-cp38-cp38-macosx_10_14_x86_64.whl", hash = "sha256:80972c9e179755295b0da63771915e7194dfa86f2804232118f914764cc2b11d"},
-    {file = "primer3_py-2.2.0-cp38-cp38-manylinux_2_17_x86_64.manylinux2014_x86_64.whl", hash = "sha256:4e0cf6e5a7efe9314a2deaaf310554eab9ae39a502753f98d26b9b058e4696ed"},
-    {file = "primer3_py-2.2.0-cp38-cp38-win_amd64.whl", hash = "sha256:22a162b9575dc85aea124e788523086f67101ab71e6d61e878c4afade12fc708"},
-    {file = "primer3_py-2.2.0-cp39-cp39-macosx_10_14_x86_64.whl", hash = "sha256:ca7a712ce9b6dc8ae70e666e2aed7d57ede2ed1d4121909df3c132babfd7f2de"},
-    {file = "primer3_py-2.2.0-cp39-cp39-macosx_11_0_arm64.whl", hash = "sha256:9bd21dcbda40c834c5d1fd6047bb0b825172ac82bbdedc558aa621fd77b01360"},
-    {file = "primer3_py-2.2.0-cp39-cp39-manylinux_2_17_x86_64.manylinux2014_x86_64.whl", hash = "sha256:6ed4fb2cc8f945326c267195204361e96c7c12ad8494b7e3a20766cb0b07b282"},
-    {file = "primer3_py-2.2.0-cp39-cp39-win_amd64.whl", hash = "sha256:22d25fee9d090e9b0b249eb35ab411bdcf8783d7795ecf38a89a62326ec1bd08"},
-    {file = "primer3_py-2.2.0.tar.gz", hash = "sha256:c71f8cccdf1e3f7f769f85c2551adff7488a1bd8f722e373b702ed25b4c1fa90"},
-]
+files = []
+develop = false
 
 [package.extras]
 dev = ["pre-commit (>=3.5.0,<3.6.0)", "pytest (>=7.4.0,<7.5.0)", "tomli (>=2.0.0,<2.1.0)"]
 docs = ["myst-parser", "sphinx", "sphinx-autodoc-typehints", "sphinx_rtd_theme (==2.0.0)"]
 
+[package.source]
+type = "git"
+url = "https://github.com/manulera/primer3-py"
+reference = "bef7f2cc18119c527098b987ffa7d23fdf748546"
+resolved_reference = "bef7f2cc18119c527098b987ffa7d23fdf748546"
+
 [[package]]
 name = "prompt-toolkit"
 version = "3.0.52"
@@ -2694,4 +2680,4 @@ test = ["pytest (>=6.0.0)", "setuptools (>=65)"]
 [metadata]
 lock-version = "2.1"
 python-versions = "^3.11"
-content-hash = "66cafb4bdee008393fc8504786d074cd2ba9d54a88978de413825a42ba8b69d5"
+content-hash = "852046784fc2debc03aad54490b2b62c24af058f38f75795b6064ad006738424"
diff --git a/pyproject.toml b/pyproject.toml
index d411499..2c2db41 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -25,7 +25,7 @@ pydantic = "^2.7.1"
 pandas = "^2.2.3"
 openpyxl = "^3.1.5"
 pyyaml = "^6.0.2"
-primer3-py = "2.2.0"
+primer3-py = {git = "https://github.com/manulera/primer3-py", rev = "bef7f2cc18119c527098b987ffa7d23fdf748546"}
 biopython = "^1.85"
 packaging = "^25.0"
 pairwise-alignments-to-msa = "^0.1.1"