diff --git a/src/compiler/checker.ts b/src/compiler/checker.ts
index 06ef246340252..ef11dc904ea19 100644
--- a/src/compiler/checker.ts
+++ b/src/compiler/checker.ts
@@ -7662,7 +7662,7 @@ namespace ts {
 
         function getFlowTypeOfReference(reference: Node, declaredType: Type, assumeInitialized: boolean, includeOuterFunctions: boolean) {
             let key: string;
-            if (!reference.flowNode || assumeInitialized && !(declaredType.flags & TypeFlags.Narrowable)) {
+            if (!reference.flowNode || assumeInitialized && (declaredType.flags & TypeFlags.NotNarrowable)) {
                 return declaredType;
             }
             const initialType = assumeInitialized ? declaredType : addNullableKind(declaredType, TypeFlags.Undefined);
diff --git a/src/compiler/types.ts b/src/compiler/types.ts
index c7e14a1003108..026ee5da9604e 100644
--- a/src/compiler/types.ts
+++ b/src/compiler/types.ts
@@ -2218,7 +2218,13 @@ namespace ts {
         ObjectType = Class | Interface | Reference | Tuple | Anonymous,
         UnionOrIntersection = Union | Intersection,
         StructuredType = ObjectType | Union | Intersection,
-        Narrowable = Any | ObjectType | Union | TypeParameter,
+
+        // 'NotNarrowable' types are types where narrowing reverts to the original type, rather than actually narrow.
+        // This is never really correct - you can _always_ narrow to an intersection with that type, _but_ we keep
+        // Void as the only non-narrowable type, since it's a non-value type construct (representing a lack of a value)
+        // and, generally speaking, narrowing `void` should fail in some way, as it is nonsensical. (`void` narrowing
+        // to `void & T`, in a structural sense, is just narrowing to T, which we wouldn't allow under normal rules)
+        NotNarrowable = Void,
         /* @internal */
         RequiresWidening = ContainsUndefinedOrNull | ContainsObjectLiteral,
         /* @internal */
diff --git a/tests/baselines/reference/typeGuardNarrowsPrimitiveIntersection.js b/tests/baselines/reference/typeGuardNarrowsPrimitiveIntersection.js
new file mode 100644
index 0000000000000..a4cba6f4ab5c1
--- /dev/null
+++ b/tests/baselines/reference/typeGuardNarrowsPrimitiveIntersection.js
@@ -0,0 +1,38 @@
+//// [typeGuardNarrowsPrimitiveIntersection.ts]
+type Tag = {__tag: any};
+declare function isNonBlank(value: string) : value is (string & Tag);
+declare function doThis(value: string & Tag): void;
+declare function doThat(value: string) : void;
+let value: string;
+if (isNonBlank(value)) {
+    doThis(value);
+} else {
+    doThat(value);
+}
+
+
+const enum Tag2 {}
+declare function isNonBlank2(value: string) : value is (string & Tag2);
+declare function doThis2(value: string & Tag2): void;
+declare function doThat2(value: string) : void;
+if (isNonBlank2(value)) {
+    doThis2(value);
+} else {
+    doThat2(value);
+}
+
+
+//// [typeGuardNarrowsPrimitiveIntersection.js]
+var value;
+if (isNonBlank(value)) {
+    doThis(value);
+}
+else {
+    doThat(value);
+}
+if (isNonBlank2(value)) {
+    doThis2(value);
+}
+else {
+    doThat2(value);
+}
diff --git a/tests/baselines/reference/typeGuardNarrowsPrimitiveIntersection.symbols b/tests/baselines/reference/typeGuardNarrowsPrimitiveIntersection.symbols
new file mode 100644
index 0000000000000..da507fb94c5dc
--- /dev/null
+++ b/tests/baselines/reference/typeGuardNarrowsPrimitiveIntersection.symbols
@@ -0,0 +1,70 @@
+=== tests/cases/conformance/expressions/typeGuards/typeGuardNarrowsPrimitiveIntersection.ts ===
+type Tag = {__tag: any};
+>Tag : Symbol(Tag, Decl(typeGuardNarrowsPrimitiveIntersection.ts, 0, 0))
+>__tag : Symbol(__tag, Decl(typeGuardNarrowsPrimitiveIntersection.ts, 0, 12))
+
+declare function isNonBlank(value: string) : value is (string & Tag);
+>isNonBlank : Symbol(isNonBlank, Decl(typeGuardNarrowsPrimitiveIntersection.ts, 0, 24))
+>value : Symbol(value, Decl(typeGuardNarrowsPrimitiveIntersection.ts, 1, 28))
+>value : Symbol(value, Decl(typeGuardNarrowsPrimitiveIntersection.ts, 1, 28))
+>Tag : Symbol(Tag, Decl(typeGuardNarrowsPrimitiveIntersection.ts, 0, 0))
+
+declare function doThis(value: string & Tag): void;
+>doThis : Symbol(doThis, Decl(typeGuardNarrowsPrimitiveIntersection.ts, 1, 69))
+>value : Symbol(value, Decl(typeGuardNarrowsPrimitiveIntersection.ts, 2, 24))
+>Tag : Symbol(Tag, Decl(typeGuardNarrowsPrimitiveIntersection.ts, 0, 0))
+
+declare function doThat(value: string) : void;
+>doThat : Symbol(doThat, Decl(typeGuardNarrowsPrimitiveIntersection.ts, 2, 51))
+>value : Symbol(value, Decl(typeGuardNarrowsPrimitiveIntersection.ts, 3, 24))
+
+let value: string;
+>value : Symbol(value, Decl(typeGuardNarrowsPrimitiveIntersection.ts, 4, 3))
+
+if (isNonBlank(value)) {
+>isNonBlank : Symbol(isNonBlank, Decl(typeGuardNarrowsPrimitiveIntersection.ts, 0, 24))
+>value : Symbol(value, Decl(typeGuardNarrowsPrimitiveIntersection.ts, 4, 3))
+
+    doThis(value);
+>doThis : Symbol(doThis, Decl(typeGuardNarrowsPrimitiveIntersection.ts, 1, 69))
+>value : Symbol(value, Decl(typeGuardNarrowsPrimitiveIntersection.ts, 4, 3))
+
+} else {
+    doThat(value);
+>doThat : Symbol(doThat, Decl(typeGuardNarrowsPrimitiveIntersection.ts, 2, 51))
+>value : Symbol(value, Decl(typeGuardNarrowsPrimitiveIntersection.ts, 4, 3))
+}
+
+
+const enum Tag2 {}
+>Tag2 : Symbol(Tag2, Decl(typeGuardNarrowsPrimitiveIntersection.ts, 9, 1))
+
+declare function isNonBlank2(value: string) : value is (string & Tag2);
+>isNonBlank2 : Symbol(isNonBlank2, Decl(typeGuardNarrowsPrimitiveIntersection.ts, 12, 18))
+>value : Symbol(value, Decl(typeGuardNarrowsPrimitiveIntersection.ts, 13, 29))
+>value : Symbol(value, Decl(typeGuardNarrowsPrimitiveIntersection.ts, 13, 29))
+>Tag2 : Symbol(Tag2, Decl(typeGuardNarrowsPrimitiveIntersection.ts, 9, 1))
+
+declare function doThis2(value: string & Tag2): void;
+>doThis2 : Symbol(doThis2, Decl(typeGuardNarrowsPrimitiveIntersection.ts, 13, 71))
+>value : Symbol(value, Decl(typeGuardNarrowsPrimitiveIntersection.ts, 14, 25))
+>Tag2 : Symbol(Tag2, Decl(typeGuardNarrowsPrimitiveIntersection.ts, 9, 1))
+
+declare function doThat2(value: string) : void;
+>doThat2 : Symbol(doThat2, Decl(typeGuardNarrowsPrimitiveIntersection.ts, 14, 53))
+>value : Symbol(value, Decl(typeGuardNarrowsPrimitiveIntersection.ts, 15, 25))
+
+if (isNonBlank2(value)) {
+>isNonBlank2 : Symbol(isNonBlank2, Decl(typeGuardNarrowsPrimitiveIntersection.ts, 12, 18))
+>value : Symbol(value, Decl(typeGuardNarrowsPrimitiveIntersection.ts, 4, 3))
+
+    doThis2(value);
+>doThis2 : Symbol(doThis2, Decl(typeGuardNarrowsPrimitiveIntersection.ts, 13, 71))
+>value : Symbol(value, Decl(typeGuardNarrowsPrimitiveIntersection.ts, 4, 3))
+
+} else {
+    doThat2(value);
+>doThat2 : Symbol(doThat2, Decl(typeGuardNarrowsPrimitiveIntersection.ts, 14, 53))
+>value : Symbol(value, Decl(typeGuardNarrowsPrimitiveIntersection.ts, 4, 3))
+}
+
diff --git a/tests/baselines/reference/typeGuardNarrowsPrimitiveIntersection.types b/tests/baselines/reference/typeGuardNarrowsPrimitiveIntersection.types
new file mode 100644
index 0000000000000..478363669b461
--- /dev/null
+++ b/tests/baselines/reference/typeGuardNarrowsPrimitiveIntersection.types
@@ -0,0 +1,76 @@
+=== tests/cases/conformance/expressions/typeGuards/typeGuardNarrowsPrimitiveIntersection.ts ===
+type Tag = {__tag: any};
+>Tag : { __tag: any; }
+>__tag : any
+
+declare function isNonBlank(value: string) : value is (string & Tag);
+>isNonBlank : (value: string) => value is string & { __tag: any; }
+>value : string
+>value : any
+>Tag : { __tag: any; }
+
+declare function doThis(value: string & Tag): void;
+>doThis : (value: string & { __tag: any; }) => void
+>value : string & { __tag: any; }
+>Tag : { __tag: any; }
+
+declare function doThat(value: string) : void;
+>doThat : (value: string) => void
+>value : string
+
+let value: string;
+>value : string
+
+if (isNonBlank(value)) {
+>isNonBlank(value) : boolean
+>isNonBlank : (value: string) => value is string & { __tag: any; }
+>value : string
+
+    doThis(value);
+>doThis(value) : void
+>doThis : (value: string & { __tag: any; }) => void
+>value : string & { __tag: any; }
+
+} else {
+    doThat(value);
+>doThat(value) : void
+>doThat : (value: string) => void
+>value : string
+}
+
+
+const enum Tag2 {}
+>Tag2 : Tag2
+
+declare function isNonBlank2(value: string) : value is (string & Tag2);
+>isNonBlank2 : (value: string) => value is string & Tag2
+>value : string
+>value : any
+>Tag2 : Tag2
+
+declare function doThis2(value: string & Tag2): void;
+>doThis2 : (value: string & Tag2) => void
+>value : string & Tag2
+>Tag2 : Tag2
+
+declare function doThat2(value: string) : void;
+>doThat2 : (value: string) => void
+>value : string
+
+if (isNonBlank2(value)) {
+>isNonBlank2(value) : boolean
+>isNonBlank2 : (value: string) => value is string & Tag2
+>value : string
+
+    doThis2(value);
+>doThis2(value) : void
+>doThis2 : (value: string & Tag2) => void
+>value : string & Tag2
+
+} else {
+    doThat2(value);
+>doThat2(value) : void
+>doThat2 : (value: string) => void
+>value : string
+}
+
diff --git a/tests/baselines/reference/typeGuardNarrowsToLiteralType.js b/tests/baselines/reference/typeGuardNarrowsToLiteralType.js
new file mode 100644
index 0000000000000..fdd2ee3fb7f75
--- /dev/null
+++ b/tests/baselines/reference/typeGuardNarrowsToLiteralType.js
@@ -0,0 +1,21 @@
+//// [typeGuardNarrowsToLiteralType.ts]
+declare function isFoo(value: string) : value is "foo";
+declare function doThis(value: "foo"): void;
+declare function doThat(value: string) : void;
+let value: string;
+if (isFoo(value)) {
+    doThis(value);
+} else {
+    doThat(value);
+}
+
+
+
+//// [typeGuardNarrowsToLiteralType.js]
+var value;
+if (isFoo(value)) {
+    doThis(value);
+}
+else {
+    doThat(value);
+}
diff --git a/tests/baselines/reference/typeGuardNarrowsToLiteralType.symbols b/tests/baselines/reference/typeGuardNarrowsToLiteralType.symbols
new file mode 100644
index 0000000000000..0d0ddc5f00dc1
--- /dev/null
+++ b/tests/baselines/reference/typeGuardNarrowsToLiteralType.symbols
@@ -0,0 +1,32 @@
+=== tests/cases/conformance/expressions/typeGuards/typeGuardNarrowsToLiteralType.ts ===
+declare function isFoo(value: string) : value is "foo";
+>isFoo : Symbol(isFoo, Decl(typeGuardNarrowsToLiteralType.ts, 0, 0))
+>value : Symbol(value, Decl(typeGuardNarrowsToLiteralType.ts, 0, 23))
+>value : Symbol(value, Decl(typeGuardNarrowsToLiteralType.ts, 0, 23))
+
+declare function doThis(value: "foo"): void;
+>doThis : Symbol(doThis, Decl(typeGuardNarrowsToLiteralType.ts, 0, 55))
+>value : Symbol(value, Decl(typeGuardNarrowsToLiteralType.ts, 1, 24))
+
+declare function doThat(value: string) : void;
+>doThat : Symbol(doThat, Decl(typeGuardNarrowsToLiteralType.ts, 1, 44))
+>value : Symbol(value, Decl(typeGuardNarrowsToLiteralType.ts, 2, 24))
+
+let value: string;
+>value : Symbol(value, Decl(typeGuardNarrowsToLiteralType.ts, 3, 3))
+
+if (isFoo(value)) {
+>isFoo : Symbol(isFoo, Decl(typeGuardNarrowsToLiteralType.ts, 0, 0))
+>value : Symbol(value, Decl(typeGuardNarrowsToLiteralType.ts, 3, 3))
+
+    doThis(value);
+>doThis : Symbol(doThis, Decl(typeGuardNarrowsToLiteralType.ts, 0, 55))
+>value : Symbol(value, Decl(typeGuardNarrowsToLiteralType.ts, 3, 3))
+
+} else {
+    doThat(value);
+>doThat : Symbol(doThat, Decl(typeGuardNarrowsToLiteralType.ts, 1, 44))
+>value : Symbol(value, Decl(typeGuardNarrowsToLiteralType.ts, 3, 3))
+}
+
+
diff --git a/tests/baselines/reference/typeGuardNarrowsToLiteralType.types b/tests/baselines/reference/typeGuardNarrowsToLiteralType.types
new file mode 100644
index 0000000000000..9835206deb9f4
--- /dev/null
+++ b/tests/baselines/reference/typeGuardNarrowsToLiteralType.types
@@ -0,0 +1,35 @@
+=== tests/cases/conformance/expressions/typeGuards/typeGuardNarrowsToLiteralType.ts ===
+declare function isFoo(value: string) : value is "foo";
+>isFoo : (value: string) => value is "foo"
+>value : string
+>value : any
+
+declare function doThis(value: "foo"): void;
+>doThis : (value: "foo") => void
+>value : "foo"
+
+declare function doThat(value: string) : void;
+>doThat : (value: string) => void
+>value : string
+
+let value: string;
+>value : string
+
+if (isFoo(value)) {
+>isFoo(value) : boolean
+>isFoo : (value: string) => value is "foo"
+>value : string
+
+    doThis(value);
+>doThis(value) : void
+>doThis : (value: "foo") => void
+>value : "foo"
+
+} else {
+    doThat(value);
+>doThat(value) : void
+>doThat : (value: string) => void
+>value : string
+}
+
+
diff --git a/tests/baselines/reference/typeGuardNarrowsToLiteralTypeUnion.js b/tests/baselines/reference/typeGuardNarrowsToLiteralTypeUnion.js
new file mode 100644
index 0000000000000..715b362c8e0c2
--- /dev/null
+++ b/tests/baselines/reference/typeGuardNarrowsToLiteralTypeUnion.js
@@ -0,0 +1,21 @@
+//// [typeGuardNarrowsToLiteralTypeUnion.ts]
+declare function isFoo(value: string) : value is ("foo" | "bar");
+declare function doThis(value: "foo" | "bar"): void;
+declare function doThat(value: string) : void;
+let value: string;
+if (isFoo(value)) {
+    doThis(value);
+} else {
+    doThat(value);
+}
+
+
+
+//// [typeGuardNarrowsToLiteralTypeUnion.js]
+var value;
+if (isFoo(value)) {
+    doThis(value);
+}
+else {
+    doThat(value);
+}
diff --git a/tests/baselines/reference/typeGuardNarrowsToLiteralTypeUnion.symbols b/tests/baselines/reference/typeGuardNarrowsToLiteralTypeUnion.symbols
new file mode 100644
index 0000000000000..356fa06a06c4a
--- /dev/null
+++ b/tests/baselines/reference/typeGuardNarrowsToLiteralTypeUnion.symbols
@@ -0,0 +1,32 @@
+=== tests/cases/conformance/expressions/typeGuards/typeGuardNarrowsToLiteralTypeUnion.ts ===
+declare function isFoo(value: string) : value is ("foo" | "bar");
+>isFoo : Symbol(isFoo, Decl(typeGuardNarrowsToLiteralTypeUnion.ts, 0, 0))
+>value : Symbol(value, Decl(typeGuardNarrowsToLiteralTypeUnion.ts, 0, 23))
+>value : Symbol(value, Decl(typeGuardNarrowsToLiteralTypeUnion.ts, 0, 23))
+
+declare function doThis(value: "foo" | "bar"): void;
+>doThis : Symbol(doThis, Decl(typeGuardNarrowsToLiteralTypeUnion.ts, 0, 65))
+>value : Symbol(value, Decl(typeGuardNarrowsToLiteralTypeUnion.ts, 1, 24))
+
+declare function doThat(value: string) : void;
+>doThat : Symbol(doThat, Decl(typeGuardNarrowsToLiteralTypeUnion.ts, 1, 52))
+>value : Symbol(value, Decl(typeGuardNarrowsToLiteralTypeUnion.ts, 2, 24))
+
+let value: string;
+>value : Symbol(value, Decl(typeGuardNarrowsToLiteralTypeUnion.ts, 3, 3))
+
+if (isFoo(value)) {
+>isFoo : Symbol(isFoo, Decl(typeGuardNarrowsToLiteralTypeUnion.ts, 0, 0))
+>value : Symbol(value, Decl(typeGuardNarrowsToLiteralTypeUnion.ts, 3, 3))
+
+    doThis(value);
+>doThis : Symbol(doThis, Decl(typeGuardNarrowsToLiteralTypeUnion.ts, 0, 65))
+>value : Symbol(value, Decl(typeGuardNarrowsToLiteralTypeUnion.ts, 3, 3))
+
+} else {
+    doThat(value);
+>doThat : Symbol(doThat, Decl(typeGuardNarrowsToLiteralTypeUnion.ts, 1, 52))
+>value : Symbol(value, Decl(typeGuardNarrowsToLiteralTypeUnion.ts, 3, 3))
+}
+
+
diff --git a/tests/baselines/reference/typeGuardNarrowsToLiteralTypeUnion.types b/tests/baselines/reference/typeGuardNarrowsToLiteralTypeUnion.types
new file mode 100644
index 0000000000000..321a8861d55f5
--- /dev/null
+++ b/tests/baselines/reference/typeGuardNarrowsToLiteralTypeUnion.types
@@ -0,0 +1,35 @@
+=== tests/cases/conformance/expressions/typeGuards/typeGuardNarrowsToLiteralTypeUnion.ts ===
+declare function isFoo(value: string) : value is ("foo" | "bar");
+>isFoo : (value: string) => value is "foo" | "bar"
+>value : string
+>value : any
+
+declare function doThis(value: "foo" | "bar"): void;
+>doThis : (value: "foo" | "bar") => void
+>value : "foo" | "bar"
+
+declare function doThat(value: string) : void;
+>doThat : (value: string) => void
+>value : string
+
+let value: string;
+>value : string
+
+if (isFoo(value)) {
+>isFoo(value) : boolean
+>isFoo : (value: string) => value is "foo" | "bar"
+>value : string
+
+    doThis(value);
+>doThis(value) : void
+>doThis : (value: "foo" | "bar") => void
+>value : "foo" | "bar"
+
+} else {
+    doThat(value);
+>doThat(value) : void
+>doThat : (value: string) => void
+>value : string
+}
+
+
diff --git a/tests/cases/conformance/expressions/typeGuards/typeGuardNarrowsPrimitiveIntersection.ts b/tests/cases/conformance/expressions/typeGuards/typeGuardNarrowsPrimitiveIntersection.ts
new file mode 100644
index 0000000000000..376a78275c83b
--- /dev/null
+++ b/tests/cases/conformance/expressions/typeGuards/typeGuardNarrowsPrimitiveIntersection.ts
@@ -0,0 +1,21 @@
+type Tag = {__tag: any};
+declare function isNonBlank(value: string) : value is (string & Tag);
+declare function doThis(value: string & Tag): void;
+declare function doThat(value: string) : void;
+let value: string;
+if (isNonBlank(value)) {
+    doThis(value);
+} else {
+    doThat(value);
+}
+
+
+const enum Tag2 {}
+declare function isNonBlank2(value: string) : value is (string & Tag2);
+declare function doThis2(value: string & Tag2): void;
+declare function doThat2(value: string) : void;
+if (isNonBlank2(value)) {
+    doThis2(value);
+} else {
+    doThat2(value);
+}
diff --git a/tests/cases/conformance/expressions/typeGuards/typeGuardNarrowsToLiteralType.ts b/tests/cases/conformance/expressions/typeGuards/typeGuardNarrowsToLiteralType.ts
new file mode 100644
index 0000000000000..3b7d5bba21ab7
--- /dev/null
+++ b/tests/cases/conformance/expressions/typeGuards/typeGuardNarrowsToLiteralType.ts
@@ -0,0 +1,10 @@
+declare function isFoo(value: string) : value is "foo";
+declare function doThis(value: "foo"): void;
+declare function doThat(value: string) : void;
+let value: string;
+if (isFoo(value)) {
+    doThis(value);
+} else {
+    doThat(value);
+}
+
diff --git a/tests/cases/conformance/expressions/typeGuards/typeGuardNarrowsToLiteralTypeUnion.ts b/tests/cases/conformance/expressions/typeGuards/typeGuardNarrowsToLiteralTypeUnion.ts
new file mode 100644
index 0000000000000..8f4726160f4b2
--- /dev/null
+++ b/tests/cases/conformance/expressions/typeGuards/typeGuardNarrowsToLiteralTypeUnion.ts
@@ -0,0 +1,10 @@
+declare function isFoo(value: string) : value is ("foo" | "bar");
+declare function doThis(value: "foo" | "bar"): void;
+declare function doThat(value: string) : void;
+let value: string;
+if (isFoo(value)) {
+    doThis(value);
+} else {
+    doThat(value);
+}
+