diff --git a/packages/framer-motion/src/animation/animate/__tests__/animate.test.tsx b/packages/framer-motion/src/animation/animate/__tests__/animate.test.tsx
index ea1f0fddd7..a8039bef99 100644
--- a/packages/framer-motion/src/animation/animate/__tests__/animate.test.tsx
+++ b/packages/framer-motion/src/animation/animate/__tests__/animate.test.tsx
@@ -373,6 +373,139 @@ describe("animate", () => {
     })
 })
 
+describe("Sequence callbacks", () => {
+    function waitForFrame(): Promise<void> {
+        return new Promise((resolve) => setTimeout(resolve, 50))
+    }
+
+    test("Scrubbing fires enter/exit at correct thresholds", async () => {
+        const element = document.createElement("div")
+        let enterCount = 0
+        let exitCount = 0
+
+        const animation = animate([
+            [element, { opacity: 1 }, { duration: 1 }],
+            [
+                {
+                    enter: () => enterCount++,
+                    exit: () => exitCount++,
+                },
+                {},
+            ],
+            [element, { opacity: 0 }, { duration: 1 }],
+        ])
+
+        expect(animation.duration).toBe(2)
+
+        animation.pause()
+
+        // Scrub to 0.5 - enter not called (callback is at t=1)
+        animation.time = 0.5
+        await waitForFrame()
+        expect(enterCount).toBe(0)
+        expect(exitCount).toBe(0)
+
+        // Scrub to 1 - enter called
+        animation.time = 1
+        await waitForFrame()
+        expect(enterCount).toBe(1)
+        expect(exitCount).toBe(0)
+
+        // Scrub to 1.5 - enter still called once (no re-fire)
+        animation.time = 1.5
+        await waitForFrame()
+        expect(enterCount).toBe(1)
+        expect(exitCount).toBe(0)
+
+        // Scrub back to 0.5 - exit called once
+        animation.time = 0.5
+        await waitForFrame()
+        expect(enterCount).toBe(1)
+        expect(exitCount).toBe(1)
+
+        // Scrub to 1.5 again - enter called twice total
+        animation.time = 1.5
+        await waitForFrame()
+        expect(enterCount).toBe(2)
+        expect(exitCount).toBe(1)
+    })
+
+    test("complete() fires enter once", async () => {
+        const element = document.createElement("div")
+        let enterCount = 0
+        let exitCount = 0
+
+        const animation = animate([
+            [element, { opacity: 1 }, { duration: 1 }],
+            [
+                {
+                    enter: () => enterCount++,
+                    exit: () => exitCount++,
+                },
+                {},
+            ],
+            [element, { opacity: 0 }, { duration: 1 }],
+        ])
+
+        animation.complete()
+        await waitForFrame()
+
+        expect(enterCount).toBe(1)
+        expect(exitCount).toBe(0)
+    })
+
+    test("cancel() without scrubbing fires neither enter nor exit", async () => {
+        const element = document.createElement("div")
+        let enterCount = 0
+        let exitCount = 0
+
+        const animation = animate([
+            [element, { opacity: 1 }, { duration: 1 }],
+            [
+                {
+                    enter: () => enterCount++,
+                    exit: () => exitCount++,
+                },
+                {},
+            ],
+            [element, { opacity: 0 }, { duration: 1 }],
+        ])
+
+        animation.cancel()
+
+        expect(enterCount).toBe(0)
+        expect(exitCount).toBe(0)
+    })
+
+    test("cancel() after scrubbing forward fires exit", async () => {
+        const element = document.createElement("div")
+        let enterCount = 0
+        let exitCount = 0
+
+        const animation = animate([
+            [element, { opacity: 1 }, { duration: 1 }],
+            [
+                {
+                    enter: () => enterCount++,
+                    exit: () => exitCount++,
+                },
+                {},
+            ],
+            [element, { opacity: 0 }, { duration: 1 }],
+        ])
+
+        animation.pause()
+        animation.time = 1.5
+        await waitForFrame()
+
+        expect(enterCount).toBe(1)
+
+        animation.cancel()
+
+        expect(exitCount).toBe(1)
+    })
+})
+
 describe("animate: Objects", () => {
     test("Types: Object to object", () => {
         animate({ x: 100 }, { x: 200 })
diff --git a/packages/framer-motion/src/animation/animate/sequence.ts b/packages/framer-motion/src/animation/animate/sequence.ts
index b26fbc4c47..4fe9a3808d 100644
--- a/packages/framer-motion/src/animation/animate/sequence.ts
+++ b/packages/framer-motion/src/animation/animate/sequence.ts
@@ -1,29 +1,76 @@
 import {
+    animateSingleValue,
     AnimationPlaybackControlsWithThen,
     AnimationScope,
     spring,
 } from "motion-dom"
 import { createAnimationsFromSequence } from "../sequence/create"
-import { AnimationSequence, SequenceOptions } from "../sequence/types"
+import {
+    AnimationSequence,
+    ResolvedSequenceCallback,
+    SequenceCallbackData,
+    SequenceOptions,
+} from "../sequence/types"
 import { animateSubject } from "./subject"
 
+/**
+ * Creates an onUpdate callback that fires sequence callbacks when time crosses their thresholds.
+ * Tracks previous progress to detect direction (forward/backward).
+ */
+function createCallbackUpdater(
+    callbacks: ResolvedSequenceCallback[],
+    totalDuration: number
+) {
+    let prevProgress = 0
+
+    return (progress: number) => {
+        const currentTime = progress * totalDuration
+
+        for (const callback of callbacks) {
+            const prevTime = prevProgress * totalDuration
+
+            if (prevTime < callback.time && currentTime >= callback.time) {
+                callback.enter?.()
+            } else if (prevTime >= callback.time && currentTime < callback.time) {
+                callback.exit?.()
+            }
+        }
+
+        prevProgress = progress
+    }
+}
+
 export function animateSequence(
     sequence: AnimationSequence,
     options?: SequenceOptions,
     scope?: AnimationScope
 ) {
     const animations: AnimationPlaybackControlsWithThen[] = []
+    const callbackData: SequenceCallbackData = { callbacks: [], totalDuration: 0 }
 
     const animationDefinitions = createAnimationsFromSequence(
         sequence,
         options,
         scope,
-        { spring }
+        { spring },
+        callbackData
     )
 
     animationDefinitions.forEach(({ keyframes, transition }, subject) => {
         animations.push(...animateSubject(subject, keyframes, transition))
     })
 
+    if (callbackData.callbacks.length) {
+        const callbackAnimation = animateSingleValue(0, 1, {
+            duration: callbackData.totalDuration,
+            ease: "linear",
+            onUpdate: createCallbackUpdater(
+                callbackData.callbacks,
+                callbackData.totalDuration
+            ),
+        })
+        animations.push(callbackAnimation)
+    }
+
     return animations
 }
diff --git a/packages/framer-motion/src/animation/sequence/__tests__/index.test.ts b/packages/framer-motion/src/animation/sequence/__tests__/index.test.ts
index 75d031dd87..d3595a61f4 100644
--- a/packages/framer-motion/src/animation/sequence/__tests__/index.test.ts
+++ b/packages/framer-motion/src/animation/sequence/__tests__/index.test.ts
@@ -838,3 +838,43 @@ describe("createAnimationsFromSequence", () => {
         expect(animations.size).toBe(0)
     })
 })
+
+describe("Sequence callbacks", () => {
+    const a = document.createElement("div")
+    const b = document.createElement("div")
+
+    test("Callbacks don't affect animation timing", () => {
+        const animations = createAnimationsFromSequence(
+            [
+                [a, { x: 100 }, { duration: 1 }],
+                [{ enter: () => {} }, {}],
+                [{ enter: () => {} }, {}],
+                [{ enter: () => {} }, {}],
+                [b, { y: 200 }, { duration: 1 }],
+            ],
+            undefined,
+            undefined,
+            { spring }
+        )
+
+        expect(animations.get(a)!.transition.x.duration).toBe(2)
+        expect(animations.get(a)!.transition.x.times).toEqual([0, 0.5, 1])
+        expect(animations.get(b)!.transition.y.times).toEqual([0, 0.5, 1])
+    })
+
+    test("Callback segments are skipped in animation definitions", () => {
+        const animations = createAnimationsFromSequence(
+            [
+                [a, { x: 100 }, { duration: 1 }],
+                [{ enter: () => {} }, { at: 0.5 }],
+            ],
+            undefined,
+            undefined,
+            { spring }
+        )
+
+        // Only the element animation, no callback artifacts
+        expect(animations.size).toBe(1)
+        expect(animations.has(a)).toBe(true)
+    })
+})
diff --git a/packages/framer-motion/src/animation/sequence/create.ts b/packages/framer-motion/src/animation/sequence/create.ts
index 07ead3c85b..b14d90e57d 100644
--- a/packages/framer-motion/src/animation/sequence/create.ts
+++ b/packages/framer-motion/src/animation/sequence/create.ts
@@ -24,7 +24,9 @@ import { resolveSubjects } from "../animate/resolve-subjects"
 import {
     AnimationSequence,
     At,
+    CallbackSegment,
     ResolvedAnimationDefinitions,
+    SequenceCallbackData,
     SequenceMap,
     SequenceOptions,
     ValueSequence,
@@ -43,7 +45,8 @@ export function createAnimationsFromSequence(
     sequence: AnimationSequence,
     { defaultTransition = {}, ...sequenceTransition }: SequenceOptions = {},
     scope?: AnimationScope,
-    generators?: { [key: string]: GeneratorFactory }
+    generators?: { [key: string]: GeneratorFactory },
+    callbackData?: SequenceCallbackData
 ): ResolvedAnimationDefinitions {
     const defaultDuration = defaultTransition.duration || 0.3
     const animationDefinitions: ResolvedAnimationDefinitions = new Map()
@@ -77,6 +80,29 @@ export function createAnimationsFromSequence(
             continue
         }
 
+        /**
+         * If this is a callback segment, extract the callback and its timing
+         */
+        if (isCallbackSegment(segment)) {
+            const [callback, options] = segment
+            const callbackTime =
+                options.at !== undefined
+                    ? calcNextTime(
+                          currentTime,
+                          options.at,
+                          prevTime,
+                          timeLabels
+                      )
+                    : currentTime
+
+            callbackData?.callbacks.push({
+                time: callbackTime,
+                enter: callback.enter,
+                exit: callback.exit,
+            })
+            continue
+        }
+
         let [subject, keyframes, transition = {}] = segment
 
         /**
@@ -390,6 +416,11 @@ export function createAnimationsFromSequence(
         }
     })
 
+    if (callbackData) {
+        callbackData.callbacks.sort((a, b) => a.time - b.time)
+        callbackData.totalDuration = totalDuration
+    }
+
     return animationDefinitions
 }
 
@@ -428,3 +459,12 @@ const isNumber = (keyframe: unknown) => typeof keyframe === "number"
 const isNumberKeyframesArray = (
     keyframes: UnresolvedValueKeyframe[]
 ): keyframes is number[] => keyframes.every(isNumber)
+
+/**
+ * Check if a segment is a callback segment: [{ enter?, exit? }, { at? }]
+ */
+function isCallbackSegment(
+    segment: any[]
+): segment is CallbackSegment {
+    return segment[0] && ("enter" in segment[0] || "exit" in segment[0])
+}
diff --git a/packages/framer-motion/src/animation/sequence/types.ts b/packages/framer-motion/src/animation/sequence/types.ts
index 2797db4e4d..da8fdc1925 100644
--- a/packages/framer-motion/src/animation/sequence/types.ts
+++ b/packages/framer-motion/src/animation/sequence/types.ts
@@ -58,6 +58,18 @@ export type ObjectSegmentWithTransition<O extends {} = {}> = [
     DynamicAnimationOptions & At
 ]
 
+/**
+ * Callback to be invoked at a specific point in the sequence.
+ * - `enter`: Called when time crosses this point moving forward
+ * - `exit`: Called when time crosses this point moving backward (for scrubbing)
+ */
+export interface SequenceCallback {
+    enter?: VoidFunction
+    exit?: VoidFunction
+}
+
+export type CallbackSegment = [SequenceCallback, At]
+
 export type Segment =
     | ObjectSegment
     | ObjectSegmentWithTransition
@@ -67,6 +79,7 @@ export type Segment =
     | MotionValueSegmentWithTransition
     | DOMSegment
     | DOMSegmentWithTransition
+    | CallbackSegment
 
 export type AnimationSequence = Segment[]
 
@@ -98,3 +111,17 @@ export type ResolvedAnimationDefinitions = Map<
     Element | MotionValue,
     ResolvedAnimationDefinition
 >
+
+/**
+ * A callback positioned at an absolute time in the sequence
+ */
+export interface ResolvedSequenceCallback {
+    time: number
+    enter?: VoidFunction
+    exit?: VoidFunction
+}
+
+export interface SequenceCallbackData {
+    callbacks: ResolvedSequenceCallback[]
+    totalDuration: number
+}