diff --git a/.github/workflows/docs_dev.yml b/.github/workflows/docs_dev.yml
index 9583f6fef..9e1c93204 100644
--- a/.github/workflows/docs_dev.yml
+++ b/.github/workflows/docs_dev.yml
@@ -17,7 +17,7 @@ jobs:
     - name: Install dependencies
       run: |
         python -m pip install --upgrade pip
-        pip install -U virtualenv setuptools wheel 'tox<4'
+        pip install -U virtualenv setuptools wheel tox
         sudo apt-get install graphviz pandoc
     - name: Build and publish
       env:
diff --git a/.github/workflows/docs_release.yml b/.github/workflows/docs_release.yml
index b52fac7a7..26aed1433 100644
--- a/.github/workflows/docs_release.yml
+++ b/.github/workflows/docs_release.yml
@@ -18,7 +18,7 @@ jobs:
     - name: Install dependencies
       run: |
         python -m pip install --upgrade pip
-        pip install -U virtualenv setuptools wheel 'tox<4'
+        pip install -U virtualenv setuptools wheel tox
         sudo apt-get install graphviz pandoc
     - name: Build and publish
       env:
diff --git a/.github/workflows/main.yml b/.github/workflows/main.yml
index 982bb3633..6fe794ef4 100644
--- a/.github/workflows/main.yml
+++ b/.github/workflows/main.yml
@@ -80,7 +80,7 @@ jobs:
           toolchain: ${{ matrix.rust }}
           targets: ${{ matrix.platform.rust-target }}
       - name: 'Install dependencies'
-        run: python -m pip install --upgrade 'tox<4'
+        run: python -m pip install --upgrade tox
       - name: 'Install binary dependencies'
         run: sudo apt-get install -y graphviz
         if: runner.os == 'Linux'
@@ -103,7 +103,7 @@ jobs:
       - name: Install Rust toolchain
         uses: dtolnay/rust-toolchain@stable
       - name: 'Install dependencies'
-        run: python -m pip install --upgrade 'tox<4'
+        run: python -m pip install --upgrade tox
       - name: 'Run rustworkx stub tests'
         run: tox -estubs
   tests_retworkx_compat:
@@ -132,7 +132,7 @@ jobs:
           toolchain: ${{ matrix.rust }}
           targets: ${{ matrix.platform.rust-target }}
       - name: 'Install dependencies'
-        run: python -m pip install --upgrade 'tox<4'
+        run: python -m pip install --upgrade tox
       - name: 'Install binary dependencies'
         run: sudo apt-get install -y graphviz
         if: runner.os == 'Linux'
@@ -202,7 +202,7 @@ jobs:
       - name: Install binary deps
         run: sudo apt-get install -y graphviz
       - name: Install deps
-        run: pip install -U 'tox<4'
+        run: pip install -U tox
       - name: Build Docs
         run: tox -edocs
       - uses: actions/upload-artifact@v3
diff --git a/tox.ini b/tox.ini
index 77451c244..80cd1304e 100644
--- a/tox.ini
+++ b/tox.ini
@@ -1,10 +1,10 @@
 [tox]
-minversion = 2.1
+minversion = 4.4.0
 envlist = py37, py38, py39, py310, py311, lint
 isolated_build = true
 
 [testenv]
-install_command = pip install -c{toxinidir}/constraints.txt -U {opts} {packages}
+install_command = python -I -m pip install -c{toxinidir}/constraints.txt -U {opts} {packages}
 setenv =
   VIRTUAL_ENV={envdir}
   LANGUAGE=en_US
@@ -19,14 +19,15 @@ deps =
 extras =
   mpl
   graphviz
-passenv = RETWORKX_TEST_PRESERVE_IMAGES RUSTWORKX_PKG_NAME
+passenv =
+  RETWORKX_TEST_PRESERVE_IMAGES
+  RUSTWORKX_PKG_NAME
 changedir = {toxinidir}/tests
 commands =
   stestr run {posargs}
 
 [testenv:lint]
 basepython = python3
-envdir = .tox/lint
 deps =
   black~=22.0
   flake8
@@ -44,7 +45,10 @@ setenv =
   {[testenv]setenv}
 deps =
   -r {toxinidir}/docs/source/requirements.txt
-passenv = {[testenv]passenv} RETWORKX_DEV_DOCS RETWORKX_LEGACY_DOCS
+passenv =
+  {[testenv]passenv}
+  RETWORKX_DEV_DOCS
+  RETWORKX_LEGACY_DOCS
 changedir = {toxinidir}/docs
 commands =
   python -m ipykernel install --user
@@ -53,14 +57,12 @@ commands =
 
 [testenv:black]
 basepython = python3
-envdir = .tox/lint
 deps =
   black~=22.0
 commands = black {posargs} '../rustworkx' '../tests' '../retworkx'
 
 [testenv:stubs]
 basepython = python3
-envdir = .tox/stubs
 deps =
   mypy==1.0.1
 commands = python -m mypy.stubtest --concise --ignore-missing-stub rustworkx.rustworkx