diff --git a/modules/nf-core/metaeuk/easypredict/main.nf b/modules/nf-core/metaeuk/easypredict/main.nf
index 4d809c2f713..5caf38f96fb 100644
--- a/modules/nf-core/metaeuk/easypredict/main.nf
+++ b/modules/nf-core/metaeuk/easypredict/main.nf
@@ -25,9 +25,17 @@ process METAEUK_EASYPREDICT {
     def args = task.ext.args ?: ''
     prefix = task.ext.prefix ?: "${meta.id}"
     """
+    if [ -d ${database} ]; then
+        ## if supplying an mmseqs database as a directory, metaeuk requires the basename of the database
+        DBBASE=`find ${database}/ -name "*.version" -exec sh -c 'file=\$(basename {}); echo \${file%%.*}' \\;`
+        DB=`echo "${database}/\${DBBASE}"`
+    else
+        DB=${database}
+    fi
+
     metaeuk easy-predict \\
         ${fasta} \\
-        ${database} \\
+        \${DB} \\
         ${prefix} \\
         tmp/ \\
         ${args}
diff --git a/tests/modules/nf-core/metaeuk/easypredict/main.nf b/tests/modules/nf-core/metaeuk/easypredict/main.nf
index 8eb73195ad0..5c3c6544b7f 100644
--- a/tests/modules/nf-core/metaeuk/easypredict/main.nf
+++ b/tests/modules/nf-core/metaeuk/easypredict/main.nf
@@ -2,18 +2,35 @@
 
 nextflow.enable.dsl = 2
 
-include { METAEUK_EASYPREDICT } from '../../../../../modules/nf-core/metaeuk/easypredict/main.nf'
+include { MMSEQS_DATABASES                                  } from '../../../../../modules/nf-core/mmseqs/databases/main.nf'
+include { METAEUK_EASYPREDICT as METAEUK_EASYPREDICT_FASTA  } from '../../../../../modules/nf-core/metaeuk/easypredict/main.nf'
+include { METAEUK_EASYPREDICT as METAEUK_EASYPREDICT_MMSEQS } from '../../../../../modules/nf-core/metaeuk/easypredict/main.nf'
 
-workflow test_metaeuk_easypredict {
+workflow test_metaeuk_easypredict_fasta {
 
     input = [
         [ id:'test', single_end:false ], // meta map
         file(params.test_data['homo_sapiens']['genome']['genome_fasta'], checkIfExists: true)
     ]
 
-    database = [
+    fasta = [
         file(params.test_data['proteomics']['database']['yeast_ups'], checkIfExists: true)
     ]
 
-    METAEUK_EASYPREDICT ( input, database )
+    METAEUK_EASYPREDICT_FASTA ( input, fasta )
+
+}
+
+workflow test_metaeuk_easypredict_mmseqs {
+
+    input = [
+        [ id:'test', single_end:false ], // meta map
+        file(params.test_data['homo_sapiens']['genome']['genome_fasta'], checkIfExists: true)
+    ]
+
+    MMSEQS_DATABASES ( 'UniProtKB/Swiss-Prot' )
+    database = MMSEQS_DATABASES.out.database
+
+    METAEUK_EASYPREDICT_MMSEQS ( input, database )
+
 }
diff --git a/tests/modules/nf-core/metaeuk/easypredict/test.yml b/tests/modules/nf-core/metaeuk/easypredict/test.yml
index 6c6d56461e1..63c9be06bd7 100644
--- a/tests/modules/nf-core/metaeuk/easypredict/test.yml
+++ b/tests/modules/nf-core/metaeuk/easypredict/test.yml
@@ -1,5 +1,5 @@
-- name: metaeuk easypredict test_metaeuk_easypredict
-  command: nextflow run ./tests/modules/nf-core/metaeuk/easypredict -entry test_metaeuk_easypredict -c ./tests/config/nextflow.config -c ./tests/modules/nf-core/metaeuk/easypredict/nextflow.config
+- name: metaeuk easypredict test_metaeuk_easypredict_fasta
+  command: nextflow run ./tests/modules/nf-core/metaeuk/easypredict -entry test_metaeuk_easypredict_fasta -c ./tests/config/nextflow.config -c ./tests/modules/nf-core/metaeuk/easypredict/nextflow.config
   tags:
     - metaeuk/easypredict
     - metaeuk
@@ -13,3 +13,27 @@
     - path: output/metaeuk/test.headersMap.tsv
       md5sum: b3628c76d7385d326bd8a7931d974cff
     - path: output/metaeuk/versions.yml
+
+- name: metaeuk easypredict test_metaeuk_easypredict_mmseqs
+  command: nextflow run ./tests/modules/nf-core/metaeuk/easypredict -entry test_metaeuk_easypredict_mmseqs -c ./tests/config/nextflow.config -c ./tests/modules/nf-core/metaeuk/easypredict/nextflow.config
+  tags:
+    - metaeuk/easypredict
+    - metaeuk
+  files:
+    - path: output/metaeuk/test.codon.fas
+    - path: output/metaeuk/test.fas
+    - path: output/metaeuk/test.gff
+    - path: output/metaeuk/test.headersMap.tsv
+    - path: output/metaeuk/versions.yml
+    - path: output/mmseqs/mmseqs_database/database
+    - path: output/mmseqs/mmseqs_database/database.dbtype
+    - path: output/mmseqs/mmseqs_database/database.index
+    - path: output/mmseqs/mmseqs_database/database.lookup
+    - path: output/mmseqs/mmseqs_database/database.source
+    - path: output/mmseqs/mmseqs_database/database.version
+    - path: output/mmseqs/mmseqs_database/database_h
+    - path: output/mmseqs/mmseqs_database/database_h.dbtype
+    - path: output/mmseqs/mmseqs_database/database_h.index
+    - path: output/mmseqs/mmseqs_database/database_mapping
+    - path: output/mmseqs/mmseqs_database/database_taxonomy
+    - path: output/mmseqs/versions.yml