diff --git a/src/async_wrap.cc b/src/async_wrap.cc
index aac2f3c911b044..ad150ff7b0ca13 100644
--- a/src/async_wrap.cc
+++ b/src/async_wrap.cc
@@ -44,6 +44,7 @@ using v8::MaybeLocal;
 using v8::Nothing;
 using v8::Number;
 using v8::Object;
+using v8::ObjectTemplate;
 using v8::PropertyAttribute;
 using v8::ReadOnly;
 using v8::String;
@@ -351,24 +352,31 @@ Local<FunctionTemplate> AsyncWrap::GetConstructorTemplate(
   return tmpl;
 }
 
-void AsyncWrap::Initialize(Local<Object> target,
-                           Local<Value> unused,
-                           Local<Context> context,
-                           void* priv) {
+void AsyncWrap::CreatePerIsolateProperties(IsolateData* isolate_data,
+                                           Local<FunctionTemplate> ctor) {
+  Isolate* isolate = isolate_data->isolate();
+  Local<ObjectTemplate> target = ctor->InstanceTemplate();
+
+  SetMethod(isolate, target, "setupHooks", SetupHooks);
+  SetMethod(isolate, target, "setCallbackTrampoline", SetCallbackTrampoline);
+  SetMethod(isolate, target, "pushAsyncContext", PushAsyncContext);
+  SetMethod(isolate, target, "popAsyncContext", PopAsyncContext);
+  SetMethod(isolate, target, "executionAsyncResource", ExecutionAsyncResource);
+  SetMethod(isolate, target, "clearAsyncIdStack", ClearAsyncIdStack);
+  SetMethod(isolate, target, "queueDestroyAsyncId", QueueDestroyAsyncId);
+  SetMethod(isolate, target, "setPromiseHooks", SetPromiseHooks);
+  SetMethod(isolate, target, "registerDestroyHook", RegisterDestroyHook);
+  AsyncWrap::GetConstructorTemplate(isolate_data);
+}
+
+void AsyncWrap::CreatePerContextProperties(Local<Object> target,
+                                           Local<Value> unused,
+                                           Local<Context> context,
+                                           void* priv) {
   Environment* env = Environment::GetCurrent(context);
   Isolate* isolate = env->isolate();
   HandleScope scope(isolate);
 
-  SetMethod(context, target, "setupHooks", SetupHooks);
-  SetMethod(context, target, "setCallbackTrampoline", SetCallbackTrampoline);
-  SetMethod(context, target, "pushAsyncContext", PushAsyncContext);
-  SetMethod(context, target, "popAsyncContext", PopAsyncContext);
-  SetMethod(context, target, "executionAsyncResource", ExecutionAsyncResource);
-  SetMethod(context, target, "clearAsyncIdStack", ClearAsyncIdStack);
-  SetMethod(context, target, "queueDestroyAsyncId", QueueDestroyAsyncId);
-  SetMethod(context, target, "setPromiseHooks", SetPromiseHooks);
-  SetMethod(context, target, "registerDestroyHook", RegisterDestroyHook);
-
   PropertyAttribute ReadOnlyDontDelete =
       static_cast<PropertyAttribute>(ReadOnly | DontDelete);
 
@@ -625,7 +633,6 @@ void AsyncWrap::AsyncReset(Local<Object> resource, double execution_async_id,
                 async_id_, trigger_async_id_);
 }
 
-
 void AsyncWrap::EmitAsyncInit(Environment* env,
                               Local<Object> object,
                               Local<String> type,
@@ -710,6 +717,9 @@ Local<Object> AsyncWrap::GetOwner(Environment* env, Local<Object> obj) {
 
 }  // namespace node
 
-NODE_BINDING_CONTEXT_AWARE_INTERNAL(async_wrap, node::AsyncWrap::Initialize)
+NODE_BINDING_CONTEXT_AWARE_INTERNAL(async_wrap,
+                                    node::AsyncWrap::CreatePerContextProperties)
+NODE_BINDING_PER_ISOLATE_INIT(async_wrap,
+                              node::AsyncWrap::CreatePerIsolateProperties)
 NODE_BINDING_EXTERNAL_REFERENCE(async_wrap,
                                 node::AsyncWrap::RegisterExternalReferences)
diff --git a/src/async_wrap.h b/src/async_wrap.h
index 735ae1f7dbe54e..ba0c1580db44a2 100644
--- a/src/async_wrap.h
+++ b/src/async_wrap.h
@@ -145,10 +145,12 @@ class AsyncWrap : public BaseObject {
       Environment* env);
 
   static void RegisterExternalReferences(ExternalReferenceRegistry* registry);
-  static void Initialize(v8::Local<v8::Object> target,
-                         v8::Local<v8::Value> unused,
-                         v8::Local<v8::Context> context,
-                         void* priv);
+  static void CreatePerContextProperties(v8::Local<v8::Object> target,
+                                         v8::Local<v8::Value> unused,
+                                         v8::Local<v8::Context> context,
+                                         void* priv);
+  static void CreatePerIsolateProperties(
+      IsolateData* isolate_data, v8::Local<v8::FunctionTemplate> target);
 
   static void GetAsyncId(const v8::FunctionCallbackInfo<v8::Value>& args);
   static void PushAsyncContext(const v8::FunctionCallbackInfo<v8::Value>& args);
diff --git a/src/encoding_binding.cc b/src/encoding_binding.cc
index d665b38cfc5f1a..38cb63d8a75643 100644
--- a/src/encoding_binding.cc
+++ b/src/encoding_binding.cc
@@ -16,10 +16,12 @@ using v8::ArrayBuffer;
 using v8::BackingStore;
 using v8::Context;
 using v8::FunctionCallbackInfo;
+using v8::FunctionTemplate;
 using v8::Isolate;
 using v8::Local;
 using v8::MaybeLocal;
 using v8::Object;
+using v8::ObjectTemplate;
 using v8::String;
 using v8::Uint8Array;
 using v8::Value;
@@ -216,20 +218,23 @@ void BindingData::ToUnicode(const v8::FunctionCallbackInfo<v8::Value>& args) {
       String::NewFromUtf8(env->isolate(), out.c_str()).ToLocalChecked());
 }
 
-void BindingData::Initialize(Local<Object> target,
-                             Local<Value> unused,
-                             Local<Context> context,
-                             void* priv) {
+void BindingData::CreatePerIsolateProperties(IsolateData* isolate_data,
+                                             Local<FunctionTemplate> ctor) {
+  Isolate* isolate = isolate_data->isolate();
+  Local<ObjectTemplate> target = ctor->InstanceTemplate();
+  SetMethod(isolate, target, "encodeInto", EncodeInto);
+  SetMethodNoSideEffect(isolate, target, "encodeUtf8String", EncodeUtf8String);
+  SetMethodNoSideEffect(isolate, target, "decodeUTF8", DecodeUTF8);
+  SetMethodNoSideEffect(isolate, target, "toASCII", ToASCII);
+  SetMethodNoSideEffect(isolate, target, "toUnicode", ToUnicode);
+}
+
+void BindingData::CreatePerContextProperties(Local<Object> target,
+                                             Local<Value> unused,
+                                             Local<Context> context,
+                                             void* priv) {
   Realm* realm = Realm::GetCurrent(context);
-  BindingData* const binding_data =
-      realm->AddBindingData<BindingData>(context, target);
-  if (binding_data == nullptr) return;
-
-  SetMethod(context, target, "encodeInto", EncodeInto);
-  SetMethodNoSideEffect(context, target, "encodeUtf8String", EncodeUtf8String);
-  SetMethodNoSideEffect(context, target, "decodeUTF8", DecodeUTF8);
-  SetMethodNoSideEffect(context, target, "toASCII", ToASCII);
-  SetMethodNoSideEffect(context, target, "toUnicode", ToUnicode);
+  realm->AddBindingData<BindingData>(context, target);
 }
 
 void BindingData::RegisterTimerExternalReferences(
@@ -245,7 +250,11 @@ void BindingData::RegisterTimerExternalReferences(
 }  // namespace node
 
 NODE_BINDING_CONTEXT_AWARE_INTERNAL(
-    encoding_binding, node::encoding_binding::BindingData::Initialize)
+    encoding_binding,
+    node::encoding_binding::BindingData::CreatePerContextProperties)
+NODE_BINDING_PER_ISOLATE_INIT(
+    encoding_binding,
+    node::encoding_binding::BindingData::CreatePerIsolateProperties)
 NODE_BINDING_EXTERNAL_REFERENCE(
     encoding_binding,
     node::encoding_binding::BindingData::RegisterTimerExternalReferences)
diff --git a/src/encoding_binding.h b/src/encoding_binding.h
index 8a009dfce27731..437aa9c5587918 100644
--- a/src/encoding_binding.h
+++ b/src/encoding_binding.h
@@ -35,10 +35,12 @@ class BindingData : public SnapshotableObject {
   static void ToASCII(const v8::FunctionCallbackInfo<v8::Value>& args);
   static void ToUnicode(const v8::FunctionCallbackInfo<v8::Value>& args);
 
-  static void Initialize(v8::Local<v8::Object> target,
-                         v8::Local<v8::Value> unused,
-                         v8::Local<v8::Context> context,
-                         void* priv);
+  static void CreatePerIsolateProperties(IsolateData* isolate_data,
+                                         v8::Local<v8::FunctionTemplate> ctor);
+  static void CreatePerContextProperties(v8::Local<v8::Object> target,
+                                         v8::Local<v8::Value> unused,
+                                         v8::Local<v8::Context> context,
+                                         void* priv);
   static void RegisterTimerExternalReferences(
       ExternalReferenceRegistry* registry);
 
diff --git a/src/handle_wrap.cc b/src/handle_wrap.cc
index 0a1b0677975122..69e2a389f9e148 100644
--- a/src/handle_wrap.cc
+++ b/src/handle_wrap.cc
@@ -154,19 +154,24 @@ void HandleWrap::OnClose(uv_handle_t* handle) {
     wrap->MakeCallback(env->handle_onclose_symbol(), 0, nullptr);
   }
 }
-
 Local<FunctionTemplate> HandleWrap::GetConstructorTemplate(Environment* env) {
-  Local<FunctionTemplate> tmpl = env->handle_wrap_ctor_template();
+  return GetConstructorTemplate(env->isolate_data());
+}
+
+Local<FunctionTemplate> HandleWrap::GetConstructorTemplate(
+    IsolateData* isolate_data) {
+  Local<FunctionTemplate> tmpl = isolate_data->handle_wrap_ctor_template();
   if (tmpl.IsEmpty()) {
-    Isolate* isolate = env->isolate();
+    Isolate* isolate = isolate_data->isolate();
     tmpl = NewFunctionTemplate(isolate, nullptr);
-    tmpl->SetClassName(FIXED_ONE_BYTE_STRING(env->isolate(), "HandleWrap"));
-    tmpl->Inherit(AsyncWrap::GetConstructorTemplate(env));
+    tmpl->SetClassName(
+        FIXED_ONE_BYTE_STRING(isolate_data->isolate(), "HandleWrap"));
+    tmpl->Inherit(AsyncWrap::GetConstructorTemplate(isolate_data));
     SetProtoMethod(isolate, tmpl, "close", HandleWrap::Close);
     SetProtoMethodNoSideEffect(isolate, tmpl, "hasRef", HandleWrap::HasRef);
     SetProtoMethod(isolate, tmpl, "ref", HandleWrap::Ref);
     SetProtoMethod(isolate, tmpl, "unref", HandleWrap::Unref);
-    env->set_handle_wrap_ctor_template(tmpl);
+    isolate_data->set_handle_wrap_ctor_template(tmpl);
   }
   return tmpl;
 }
diff --git a/src/handle_wrap.h b/src/handle_wrap.h
index a86f8b41c44a72..cc3273432804bf 100644
--- a/src/handle_wrap.h
+++ b/src/handle_wrap.h
@@ -76,6 +76,8 @@ class HandleWrap : public AsyncWrap {
   virtual void Close(
       v8::Local<v8::Value> close_callback = v8::Local<v8::Value>());
 
+  static v8::Local<v8::FunctionTemplate> GetConstructorTemplate(
+      IsolateData* isolate_data);
   static v8::Local<v8::FunctionTemplate> GetConstructorTemplate(
       Environment* env);
   static void RegisterExternalReferences(ExternalReferenceRegistry* registry);
diff --git a/src/node_binding.h b/src/node_binding.h
index 1b024774e120a9..d6e59d19ea4652 100644
--- a/src/node_binding.h
+++ b/src/node_binding.h
@@ -31,8 +31,16 @@ static_assert(static_cast<int>(NM_F_LINKED) ==
 #endif
 
 #define NODE_BINDINGS_WITH_PER_ISOLATE_INIT(V)                                 \
+  V(async_wrap)                                                                \
+  V(blob)                                                                      \
   V(builtins)                                                                  \
+  V(contextify)                                                                \
+  V(encoding_binding)                                                          \
+  V(fs)                                                                        \
+  V(timers)                                                                    \
+  V(process_methods)                                                           \
   V(performance)                                                               \
+  V(url)                                                                       \
   V(worker)                                                                    \
   NODE_BUILTIN_ICU_BINDINGS(V)
 
diff --git a/src/node_blob.cc b/src/node_blob.cc
index 4d249a9cbda01c..a7b83f088f0777 100644
--- a/src/node_blob.cc
+++ b/src/node_blob.cc
@@ -29,6 +29,7 @@ using v8::Int32;
 using v8::Isolate;
 using v8::Local;
 using v8::Object;
+using v8::ObjectTemplate;
 using v8::String;
 using v8::Uint32;
 using v8::Undefined;
@@ -107,23 +108,25 @@ void BlobFromFilePath(const FunctionCallbackInfo<Value>& args) {
 }
 }  // namespace
 
-void Blob::Initialize(
-    Local<Object> target,
-    Local<Value> unused,
-    Local<Context> context,
-    void* priv) {
-  Realm* realm = Realm::GetCurrent(context);
+void Blob::CreatePerIsolateProperties(IsolateData* isolate_data,
+                                      Local<FunctionTemplate> ctor) {
+  Isolate* isolate = isolate_data->isolate();
+  Local<ObjectTemplate> target = ctor->InstanceTemplate();
 
-  BlobBindingData* const binding_data =
-      realm->AddBindingData<BlobBindingData>(context, target);
-  if (binding_data == nullptr) return;
+  SetMethod(isolate, target, "createBlob", New);
+  SetMethod(isolate, target, "storeDataObject", StoreDataObject);
+  SetMethod(isolate, target, "getDataObject", GetDataObject);
+  SetMethod(isolate, target, "revokeObjectURL", RevokeObjectURL);
+  SetMethod(isolate, target, "concat", Concat);
+  SetMethod(isolate, target, "createBlobFromFilePath", BlobFromFilePath);
+}
 
-  SetMethod(context, target, "createBlob", New);
-  SetMethod(context, target, "storeDataObject", StoreDataObject);
-  SetMethod(context, target, "getDataObject", GetDataObject);
-  SetMethod(context, target, "revokeObjectURL", RevokeObjectURL);
-  SetMethod(context, target, "concat", Concat);
-  SetMethod(context, target, "createBlobFromFilePath", BlobFromFilePath);
+void Blob::CreatePerContextProperties(Local<Object> target,
+                                      Local<Value> unused,
+                                      Local<Context> context,
+                                      void* priv) {
+  Realm* realm = Realm::GetCurrent(context);
+  realm->AddBindingData<BlobBindingData>(context, target);
 }
 
 Local<FunctionTemplate> Blob::GetConstructorTemplate(Environment* env) {
@@ -562,5 +565,7 @@ void Blob::RegisterExternalReferences(ExternalReferenceRegistry* registry) {
 
 }  // namespace node
 
-NODE_BINDING_CONTEXT_AWARE_INTERNAL(blob, node::Blob::Initialize)
+NODE_BINDING_CONTEXT_AWARE_INTERNAL(blob,
+                                    node::Blob::CreatePerContextProperties)
+NODE_BINDING_PER_ISOLATE_INIT(blob, node::Blob::CreatePerIsolateProperties)
 NODE_BINDING_EXTERNAL_REFERENCE(blob, node::Blob::RegisterExternalReferences)
diff --git a/src/node_blob.h b/src/node_blob.h
index 5007f788482d2a..96468534916e22 100644
--- a/src/node_blob.h
+++ b/src/node_blob.h
@@ -26,11 +26,12 @@ class Blob : public BaseObject {
   static void RegisterExternalReferences(
       ExternalReferenceRegistry* registry);
 
-  static void Initialize(
-      v8::Local<v8::Object> target,
-      v8::Local<v8::Value> unused,
-      v8::Local<v8::Context> context,
-      void* priv);
+  static void CreatePerIsolateProperties(IsolateData* isolate_data,
+                                         v8::Local<v8::FunctionTemplate> ctor);
+  static void CreatePerContextProperties(v8::Local<v8::Object> target,
+                                         v8::Local<v8::Value> unused,
+                                         v8::Local<v8::Context> context,
+                                         void* priv);
 
   static void New(const v8::FunctionCallbackInfo<v8::Value>& args);
   static void GetReader(const v8::FunctionCallbackInfo<v8::Value>& args);
diff --git a/src/node_contextify.cc b/src/node_contextify.cc
index a21acf06a32781..7f9f71ba74223a 100644
--- a/src/node_contextify.cc
+++ b/src/node_contextify.cc
@@ -114,7 +114,6 @@ BaseObjectPtr<ContextifyContext> ContextifyContext::New(
     Local<Object> sandbox_obj,
     const ContextOptions& options) {
   HandleScope scope(env->isolate());
-  InitializeGlobalTemplates(env->isolate_data());
   Local<ObjectTemplate> object_template = env->contextify_global_template();
   DCHECK(!object_template.IsEmpty());
   const SnapshotData* snapshot_data = env->isolate_data()->snapshot_data();
@@ -169,9 +168,6 @@ ContextifyContext::~ContextifyContext() {
 }
 
 void ContextifyContext::InitializeGlobalTemplates(IsolateData* isolate_data) {
-  if (!isolate_data->contextify_global_template().IsEmpty()) {
-    return;
-  }
   DCHECK(isolate_data->contextify_wrapper_template().IsEmpty());
   Local<FunctionTemplate> global_func_template =
       FunctionTemplate::New(isolate_data->isolate());
@@ -322,11 +318,12 @@ BaseObjectPtr<ContextifyContext> ContextifyContext::New(
   return result;
 }
 
-void ContextifyContext::Init(Environment* env, Local<Object> target) {
-  Local<Context> context = env->context();
-  SetMethod(context, target, "makeContext", MakeContext);
-  SetMethod(context, target, "isContext", IsContext);
-  SetMethod(context, target, "compileFunction", CompileFunction);
+void ContextifyContext::CreatePerIsolateProperties(
+    IsolateData* isolate_data, Local<ObjectTemplate> target) {
+  Isolate* isolate = isolate_data->isolate();
+  SetMethod(isolate, target, "makeContext", MakeContext);
+  SetMethod(isolate, target, "isContext", IsContext);
+  SetMethod(isolate, target, "compileFunction", CompileFunction);
 }
 
 void ContextifyContext::RegisterExternalReferences(
@@ -735,11 +732,10 @@ void ContextifyContext::IndexedPropertyDeleterCallback(
   args.GetReturnValue().Set(false);
 }
 
-void ContextifyScript::Init(Environment* env, Local<Object> target) {
-  Isolate* isolate = env->isolate();
-  HandleScope scope(env->isolate());
-  Local<String> class_name =
-      FIXED_ONE_BYTE_STRING(env->isolate(), "ContextifyScript");
+void ContextifyScript::CreatePerIsolateProperties(
+    IsolateData* isolate_data, Local<ObjectTemplate> target) {
+  Isolate* isolate = isolate_data->isolate();
+  Local<String> class_name = FIXED_ONE_BYTE_STRING(isolate, "ContextifyScript");
 
   Local<FunctionTemplate> script_tmpl = NewFunctionTemplate(isolate, New);
   script_tmpl->InstanceTemplate()->SetInternalFieldCount(
@@ -748,11 +744,8 @@ void ContextifyScript::Init(Environment* env, Local<Object> target) {
   SetProtoMethod(isolate, script_tmpl, "createCachedData", CreateCachedData);
   SetProtoMethod(isolate, script_tmpl, "runInContext", RunInContext);
 
-  Local<Context> context = env->context();
-
-  target->Set(context, class_name,
-      script_tmpl->GetFunction(context).ToLocalChecked()).Check();
-  env->set_script_context_constructor_template(script_tmpl);
+  target->Set(isolate, "ContextifyScript", script_tmpl);
+  isolate_data->set_script_context_constructor_template(script_tmpl);
 }
 
 void ContextifyScript::RegisterExternalReferences(
@@ -1382,15 +1375,15 @@ void MicrotaskQueueWrap::New(const FunctionCallbackInfo<Value>& args) {
   new MicrotaskQueueWrap(Environment::GetCurrent(args), args.This());
 }
 
-void MicrotaskQueueWrap::Init(Environment* env, Local<Object> target) {
-  Isolate* isolate = env->isolate();
+void MicrotaskQueueWrap::CreatePerIsolateProperties(
+    IsolateData* isolate_data, Local<ObjectTemplate> target) {
+  Isolate* isolate = isolate_data->isolate();
   HandleScope scope(isolate);
-  Local<Context> context = env->context();
   Local<FunctionTemplate> tmpl = NewFunctionTemplate(isolate, New);
   tmpl->InstanceTemplate()->SetInternalFieldCount(
       ContextifyScript::kInternalFieldCount);
-  env->set_microtask_queue_ctor_template(tmpl);
-  SetConstructorFunction(context, target, "MicrotaskQueue", tmpl);
+  isolate_data->set_microtask_queue_ctor_template(tmpl);
+  SetConstructorFunction(isolate, target, "MicrotaskQueue", tmpl);
 }
 
 void MicrotaskQueueWrap::RegisterExternalReferences(
@@ -1398,30 +1391,37 @@ void MicrotaskQueueWrap::RegisterExternalReferences(
   registry->Register(New);
 }
 
-void Initialize(Local<Object> target,
-                Local<Value> unused,
-                Local<Context> context,
-                void* priv) {
-  Environment* env = Environment::GetCurrent(context);
-  Isolate* isolate = env->isolate();
-  ContextifyContext::Init(env, target);
-  ContextifyScript::Init(env, target);
-  MicrotaskQueueWrap::Init(env, target);
+void CreatePerIsolateProperties(IsolateData* isolate_data,
+                                Local<FunctionTemplate> ctor) {
+  Isolate* isolate = isolate_data->isolate();
+  Local<ObjectTemplate> target = ctor->InstanceTemplate();
+  ContextifyContext::CreatePerIsolateProperties(isolate_data, target);
+  ContextifyScript::CreatePerIsolateProperties(isolate_data, target);
+  MicrotaskQueueWrap::CreatePerIsolateProperties(isolate_data, target);
 
-  SetMethod(context, target, "startSigintWatchdog", StartSigintWatchdog);
-  SetMethod(context, target, "stopSigintWatchdog", StopSigintWatchdog);
+  SetMethod(isolate, target, "startSigintWatchdog", StartSigintWatchdog);
+  SetMethod(isolate, target, "stopSigintWatchdog", StopSigintWatchdog);
   // Used in tests.
   SetMethodNoSideEffect(
-      context, target, "watchdogHasPendingSigint", WatchdogHasPendingSigint);
+      isolate, target, "watchdogHasPendingSigint", WatchdogHasPendingSigint);
 
   {
-    Local<FunctionTemplate> tpl = FunctionTemplate::New(env->isolate());
-    tpl->SetClassName(FIXED_ONE_BYTE_STRING(env->isolate(), "CompiledFnEntry"));
+    Local<FunctionTemplate> tpl = FunctionTemplate::New(isolate);
+    tpl->SetClassName(FIXED_ONE_BYTE_STRING(isolate, "CompiledFnEntry"));
     tpl->InstanceTemplate()->SetInternalFieldCount(
         CompiledFnEntry::kInternalFieldCount);
 
-    env->set_compiled_fn_entry_template(tpl->InstanceTemplate());
+    isolate_data->set_compiled_fn_entry_template(tpl->InstanceTemplate());
   }
+  SetMethod(isolate, target, "measureMemory", MeasureMemory);
+}
+
+static void CreatePerContextProperties(Local<Object> target,
+                                       Local<Value> unused,
+                                       Local<Context> context,
+                                       void* priv) {
+  Environment* env = Environment::GetCurrent(context);
+  Isolate* isolate = env->isolate();
 
   Local<Object> constants = Object::New(env->isolate());
   Local<Object> measure_memory = Object::New(env->isolate());
@@ -1447,8 +1447,6 @@ void Initialize(Local<Object> target,
   READONLY_PROPERTY(constants, "measureMemory", measure_memory);
 
   target->Set(context, env->constants_string(), constants).Check();
-
-  SetMethod(context, target, "measureMemory", MeasureMemory);
 }
 
 void RegisterExternalReferences(ExternalReferenceRegistry* registry) {
@@ -1464,6 +1462,9 @@ void RegisterExternalReferences(ExternalReferenceRegistry* registry) {
 }  // namespace contextify
 }  // namespace node
 
-NODE_BINDING_CONTEXT_AWARE_INTERNAL(contextify, node::contextify::Initialize)
+NODE_BINDING_CONTEXT_AWARE_INTERNAL(
+    contextify, node::contextify::CreatePerContextProperties)
+NODE_BINDING_PER_ISOLATE_INIT(contextify,
+                              node::contextify::CreatePerIsolateProperties)
 NODE_BINDING_EXTERNAL_REFERENCE(contextify,
                                 node::contextify::RegisterExternalReferences)
diff --git a/src/node_contextify.h b/src/node_contextify.h
index 76c89318bb6cbf..3160160521e0fe 100644
--- a/src/node_contextify.h
+++ b/src/node_contextify.h
@@ -18,7 +18,8 @@ class MicrotaskQueueWrap : public BaseObject {
 
   const std::shared_ptr<v8::MicrotaskQueue>& microtask_queue() const;
 
-  static void Init(Environment* env, v8::Local<v8::Object> target);
+  static void CreatePerIsolateProperties(IsolateData* isolate_data,
+                                         v8::Local<v8::ObjectTemplate> target);
   static void RegisterExternalReferences(ExternalReferenceRegistry* registry);
   static void New(const v8::FunctionCallbackInfo<v8::Value>& args);
 
@@ -58,7 +59,8 @@ class ContextifyContext : public BaseObject {
       v8::Local<v8::ObjectTemplate> object_template,
       const SnapshotData* snapshot_data,
       v8::MicrotaskQueue* queue);
-  static void Init(Environment* env, v8::Local<v8::Object> target);
+  static void CreatePerIsolateProperties(IsolateData* isolate_data,
+                                         v8::Local<v8::ObjectTemplate> target);
   static void RegisterExternalReferences(ExternalReferenceRegistry* registry);
 
   static ContextifyContext* ContextFromContextifiedSandbox(
@@ -156,7 +158,8 @@ class ContextifyScript : public BaseObject {
   ContextifyScript(Environment* env, v8::Local<v8::Object> object);
   ~ContextifyScript() override;
 
-  static void Init(Environment* env, v8::Local<v8::Object> target);
+  static void CreatePerIsolateProperties(IsolateData* isolate_data,
+                                         v8::Local<v8::ObjectTemplate> target);
   static void RegisterExternalReferences(ExternalReferenceRegistry* registry);
   static void New(const v8::FunctionCallbackInfo<v8::Value>& args);
   static bool InstanceOf(Environment* env, const v8::Local<v8::Value>& args);
diff --git a/src/node_file.cc b/src/node_file.cc
index dc9e1a1606a78a..ed7ec2902f69fa 100644
--- a/src/node_file.cc
+++ b/src/node_file.cc
@@ -74,7 +74,6 @@ using v8::Object;
 using v8::ObjectTemplate;
 using v8::Promise;
 using v8::String;
-using v8::Symbol;
 using v8::Undefined;
 using v8::Value;
 
@@ -2827,121 +2826,117 @@ InternalFieldInfoBase* BindingData::Serialize(int index) {
   return info;
 }
 
-void Initialize(Local<Object> target,
-                Local<Value> unused,
-                Local<Context> context,
-                void* priv) {
-  Realm* realm = Realm::GetCurrent(context);
-  Environment* env = realm->env();
-  Isolate* isolate = env->isolate();
-  BindingData* const binding_data =
-      realm->AddBindingData<BindingData>(context, target);
-  if (binding_data == nullptr) return;
-
-  SetMethod(context, target, "access", Access);
-  SetMethod(context, target, "close", Close);
-  SetMethod(context, target, "open", Open);
-  SetMethod(context, target, "openFileHandle", OpenFileHandle);
-  SetMethod(context, target, "read", Read);
-  SetMethod(context, target, "readBuffers", ReadBuffers);
-  SetMethod(context, target, "fdatasync", Fdatasync);
-  SetMethod(context, target, "fsync", Fsync);
-  SetMethod(context, target, "rename", Rename);
-  SetMethod(context, target, "ftruncate", FTruncate);
-  SetMethod(context, target, "rmdir", RMDir);
-  SetMethod(context, target, "mkdir", MKDir);
-  SetMethod(context, target, "readdir", ReadDir);
-  SetMethod(context, target, "internalModuleReadJSON", InternalModuleReadJSON);
-  SetMethod(context, target, "internalModuleStat", InternalModuleStat);
-  SetMethod(context, target, "stat", Stat);
-  SetMethod(context, target, "lstat", LStat);
-  SetMethod(context, target, "fstat", FStat);
-  SetMethod(context, target, "statfs", StatFs);
-  SetMethod(context, target, "link", Link);
-  SetMethod(context, target, "symlink", Symlink);
-  SetMethod(context, target, "readlink", ReadLink);
-  SetMethod(context, target, "unlink", Unlink);
-  SetMethod(context, target, "writeBuffer", WriteBuffer);
-  SetMethod(context, target, "writeBuffers", WriteBuffers);
-  SetMethod(context, target, "writeString", WriteString);
-  SetMethod(context, target, "realpath", RealPath);
-  SetMethod(context, target, "copyFile", CopyFile);
-
-  SetMethod(context, target, "chmod", Chmod);
-  SetMethod(context, target, "fchmod", FChmod);
-
-  SetMethod(context, target, "chown", Chown);
-  SetMethod(context, target, "fchown", FChown);
-  SetMethod(context, target, "lchown", LChown);
-
-  SetMethod(context, target, "utimes", UTimes);
-  SetMethod(context, target, "futimes", FUTimes);
-  SetMethod(context, target, "lutimes", LUTimes);
-
-  SetMethod(context, target, "mkdtemp", Mkdtemp);
-
-  target
-      ->Set(context,
-            FIXED_ONE_BYTE_STRING(isolate, "kFsStatsFieldsNumber"),
-            Integer::New(
-                isolate,
-                static_cast<int32_t>(FsStatsOffset::kFsStatsFieldsNumber)))
-      .Check();
-
-  StatWatcher::Initialize(env, target);
+static void CreatePerIsolateProperties(IsolateData* isolate_data,
+                                       Local<FunctionTemplate> ctor) {
+  Isolate* isolate = isolate_data->isolate();
+  Local<ObjectTemplate> target = ctor->InstanceTemplate();
+
+  SetMethod(isolate, target, "access", Access);
+  SetMethod(isolate, target, "close", Close);
+  SetMethod(isolate, target, "open", Open);
+  SetMethod(isolate, target, "openFileHandle", OpenFileHandle);
+  SetMethod(isolate, target, "read", Read);
+  SetMethod(isolate, target, "readBuffers", ReadBuffers);
+  SetMethod(isolate, target, "fdatasync", Fdatasync);
+  SetMethod(isolate, target, "fsync", Fsync);
+  SetMethod(isolate, target, "rename", Rename);
+  SetMethod(isolate, target, "ftruncate", FTruncate);
+  SetMethod(isolate, target, "rmdir", RMDir);
+  SetMethod(isolate, target, "mkdir", MKDir);
+  SetMethod(isolate, target, "readdir", ReadDir);
+  SetMethod(isolate, target, "internalModuleReadJSON", InternalModuleReadJSON);
+  SetMethod(isolate, target, "internalModuleStat", InternalModuleStat);
+  SetMethod(isolate, target, "stat", Stat);
+  SetMethod(isolate, target, "lstat", LStat);
+  SetMethod(isolate, target, "fstat", FStat);
+  SetMethod(isolate, target, "statfs", StatFs);
+  SetMethod(isolate, target, "link", Link);
+  SetMethod(isolate, target, "symlink", Symlink);
+  SetMethod(isolate, target, "readlink", ReadLink);
+  SetMethod(isolate, target, "unlink", Unlink);
+  SetMethod(isolate, target, "writeBuffer", WriteBuffer);
+  SetMethod(isolate, target, "writeBuffers", WriteBuffers);
+  SetMethod(isolate, target, "writeString", WriteString);
+  SetMethod(isolate, target, "realpath", RealPath);
+  SetMethod(isolate, target, "copyFile", CopyFile);
+
+  SetMethod(isolate, target, "chmod", Chmod);
+  SetMethod(isolate, target, "fchmod", FChmod);
+
+  SetMethod(isolate, target, "chown", Chown);
+  SetMethod(isolate, target, "fchown", FChown);
+  SetMethod(isolate, target, "lchown", LChown);
+
+  SetMethod(isolate, target, "utimes", UTimes);
+  SetMethod(isolate, target, "futimes", FUTimes);
+  SetMethod(isolate, target, "lutimes", LUTimes);
+
+  SetMethod(isolate, target, "mkdtemp", Mkdtemp);
+
+  StatWatcher::CreatePerIsolateProperties(isolate_data, ctor);
+
+  target->Set(
+      FIXED_ONE_BYTE_STRING(isolate, "kFsStatsFieldsNumber"),
+      Integer::New(isolate,
+                   static_cast<int32_t>(FsStatsOffset::kFsStatsFieldsNumber)));
 
   // Create FunctionTemplate for FSReqCallback
   Local<FunctionTemplate> fst = NewFunctionTemplate(isolate, NewFSReqCallback);
   fst->InstanceTemplate()->SetInternalFieldCount(
       FSReqBase::kInternalFieldCount);
-  fst->Inherit(AsyncWrap::GetConstructorTemplate(env));
-  SetConstructorFunction(context, target, "FSReqCallback", fst);
+  fst->Inherit(AsyncWrap::GetConstructorTemplate(isolate_data));
+  SetConstructorFunction(isolate, target, "FSReqCallback", fst);
 
   // Create FunctionTemplate for FileHandleReadWrap. There’s no need
   // to do anything in the constructor, so we only store the instance template.
   Local<FunctionTemplate> fh_rw = FunctionTemplate::New(isolate);
   fh_rw->InstanceTemplate()->SetInternalFieldCount(
       FSReqBase::kInternalFieldCount);
-  fh_rw->Inherit(AsyncWrap::GetConstructorTemplate(env));
+  fh_rw->Inherit(AsyncWrap::GetConstructorTemplate(isolate_data));
   Local<String> fhWrapString =
       FIXED_ONE_BYTE_STRING(isolate, "FileHandleReqWrap");
   fh_rw->SetClassName(fhWrapString);
-  env->set_filehandlereadwrap_template(
-      fst->InstanceTemplate());
+  isolate_data->set_filehandlereadwrap_template(fst->InstanceTemplate());
 
   // Create Function Template for FSReqPromise
   Local<FunctionTemplate> fpt = FunctionTemplate::New(isolate);
-  fpt->Inherit(AsyncWrap::GetConstructorTemplate(env));
+  fpt->Inherit(AsyncWrap::GetConstructorTemplate(isolate_data));
   Local<String> promiseString =
       FIXED_ONE_BYTE_STRING(isolate, "FSReqPromise");
   fpt->SetClassName(promiseString);
   Local<ObjectTemplate> fpo = fpt->InstanceTemplate();
   fpo->SetInternalFieldCount(FSReqBase::kInternalFieldCount);
-  env->set_fsreqpromise_constructor_template(fpo);
+  isolate_data->set_fsreqpromise_constructor_template(fpo);
 
   // Create FunctionTemplate for FileHandle
   Local<FunctionTemplate> fd = NewFunctionTemplate(isolate, FileHandle::New);
-  fd->Inherit(AsyncWrap::GetConstructorTemplate(env));
+  fd->Inherit(AsyncWrap::GetConstructorTemplate(isolate_data));
   SetProtoMethod(isolate, fd, "close", FileHandle::Close);
   SetProtoMethod(isolate, fd, "releaseFD", FileHandle::ReleaseFD);
   Local<ObjectTemplate> fdt = fd->InstanceTemplate();
   fdt->SetInternalFieldCount(FileHandle::kInternalFieldCount);
-  StreamBase::AddMethods(env, fd);
-  SetConstructorFunction(context, target, "FileHandle", fd);
-  env->set_fd_constructor_template(fdt);
+  StreamBase::AddMethods(isolate_data, fd);
+  SetConstructorFunction(isolate, target, "FileHandle", fd);
+  isolate_data->set_fd_constructor_template(fdt);
 
   // Create FunctionTemplate for FileHandle::CloseReq
   Local<FunctionTemplate> fdclose = FunctionTemplate::New(isolate);
   fdclose->SetClassName(FIXED_ONE_BYTE_STRING(isolate,
                         "FileHandleCloseReq"));
-  fdclose->Inherit(AsyncWrap::GetConstructorTemplate(env));
+  fdclose->Inherit(AsyncWrap::GetConstructorTemplate(isolate_data));
   Local<ObjectTemplate> fdcloset = fdclose->InstanceTemplate();
   fdcloset->SetInternalFieldCount(FSReqBase::kInternalFieldCount);
-  env->set_fdclose_constructor_template(fdcloset);
+  isolate_data->set_fdclose_constructor_template(fdcloset);
 
-  target->Set(context,
-              FIXED_ONE_BYTE_STRING(isolate, "kUsePromises"),
-              env->fs_use_promises_symbol()).Check();
+  target->Set(isolate, "kUsePromises", isolate_data->fs_use_promises_symbol());
+}
+
+static void CreatePerContextProperties(Local<Object> target,
+                                       Local<Value> unused,
+                                       Local<Context> context,
+                                       void* priv) {
+  Realm* realm = Realm::GetCurrent(context);
+  realm->AddBindingData<BindingData>(context, target);
 }
 
 BindingData* FSReqBase::binding_data() {
@@ -3004,5 +2999,6 @@ void RegisterExternalReferences(ExternalReferenceRegistry* registry) {
 
 }  // end namespace node
 
-NODE_BINDING_CONTEXT_AWARE_INTERNAL(fs, node::fs::Initialize)
+NODE_BINDING_CONTEXT_AWARE_INTERNAL(fs, node::fs::CreatePerContextProperties)
+NODE_BINDING_PER_ISOLATE_INIT(fs, node::fs::CreatePerIsolateProperties)
 NODE_BINDING_EXTERNAL_REFERENCE(fs, node::fs::RegisterExternalReferences)
diff --git a/src/node_process.h b/src/node_process.h
index 5af062e63ea49b..cb8c7962825f46 100644
--- a/src/node_process.h
+++ b/src/node_process.h
@@ -48,7 +48,8 @@ void PatchProcessObject(const v8::FunctionCallbackInfo<v8::Value>& args);
 namespace process {
 class BindingData : public SnapshotableObject {
  public:
-  void AddMethods();
+  static void AddMethods(v8::Isolate* isolate,
+                         v8::Local<v8::ObjectTemplate> target);
   static void RegisterExternalReferences(ExternalReferenceRegistry* registry);
 
   using InternalFieldInfo = InternalFieldInfoBase;
diff --git a/src/node_process_methods.cc b/src/node_process_methods.cc
index 93657860379fdf..bd0ba33d7d8dd9 100644
--- a/src/node_process_methods.cc
+++ b/src/node_process_methods.cc
@@ -41,6 +41,7 @@ using v8::CFunction;
 using v8::Context;
 using v8::Float64Array;
 using v8::FunctionCallbackInfo;
+using v8::FunctionTemplate;
 using v8::HeapStatistics;
 using v8::Integer;
 using v8::Isolate;
@@ -49,6 +50,7 @@ using v8::Maybe;
 using v8::NewStringType;
 using v8::Number;
 using v8::Object;
+using v8::ObjectTemplate;
 using v8::String;
 using v8::Uint32;
 using v8::Value;
@@ -478,11 +480,11 @@ BindingData::BindingData(Realm* realm, v8::Local<v8::Object> object)
 v8::CFunction BindingData::fast_number_(v8::CFunction::Make(FastNumber));
 v8::CFunction BindingData::fast_bigint_(v8::CFunction::Make(FastBigInt));
 
-void BindingData::AddMethods() {
-  Local<Context> ctx = env()->context();
-  SetFastMethodNoSideEffect(ctx, object(), "hrtime", SlowNumber, &fast_number_);
+void BindingData::AddMethods(Isolate* isolate, Local<ObjectTemplate> target) {
   SetFastMethodNoSideEffect(
-      ctx, object(), "hrtimeBigInt", SlowBigInt, &fast_bigint_);
+      isolate, target, "hrtime", SlowNumber, &fast_number_);
+  SetFastMethodNoSideEffect(
+      isolate, target, "hrtimeBigInt", SlowBigInt, &fast_bigint_);
 }
 
 void BindingData::RegisterExternalReferences(
@@ -569,44 +571,45 @@ void BindingData::Deserialize(Local<Context> context,
   CHECK_NOT_NULL(binding);
 }
 
-static void Initialize(Local<Object> target,
-                       Local<Value> unused,
-                       Local<Context> context,
-                       void* priv) {
-  Realm* realm = Realm::GetCurrent(context);
-  Environment* env = realm->env();
-  BindingData* const binding_data =
-      realm->AddBindingData<BindingData>(context, target);
-  if (binding_data == nullptr) return;
-  binding_data->AddMethods();
+static void CreatePerIsolateProperties(IsolateData* isolate_data,
+                                       Local<FunctionTemplate> ctor) {
+  Isolate* isolate = isolate_data->isolate();
+  Local<ObjectTemplate> target = ctor->InstanceTemplate();
 
+  BindingData::AddMethods(isolate, target);
   // define various internal methods
-  if (env->owns_process_state()) {
-    SetMethod(context, target, "_debugProcess", DebugProcess);
-    SetMethod(context, target, "abort", Abort);
-    SetMethod(context, target, "causeSegfault", CauseSegfault);
-    SetMethod(context, target, "chdir", Chdir);
-  }
-
-  SetMethod(context, target, "umask", Umask);
-  SetMethod(context, target, "memoryUsage", MemoryUsage);
-  SetMethod(context, target, "constrainedMemory", GetConstrainedMemory);
-  SetMethod(context, target, "rss", Rss);
-  SetMethod(context, target, "cpuUsage", CPUUsage);
-  SetMethod(context, target, "resourceUsage", ResourceUsage);
-
-  SetMethod(context, target, "_debugEnd", DebugEnd);
-  SetMethod(context, target, "_getActiveRequests", GetActiveRequests);
-  SetMethod(context, target, "_getActiveHandles", GetActiveHandles);
-  SetMethod(context, target, "getActiveResourcesInfo", GetActiveResourcesInfo);
-  SetMethod(context, target, "_kill", Kill);
-  SetMethod(context, target, "_rawDebug", RawDebug);
-
-  SetMethodNoSideEffect(context, target, "cwd", Cwd);
-  SetMethod(context, target, "dlopen", binding::DLOpen);
-  SetMethod(context, target, "reallyExit", ReallyExit);
-  SetMethodNoSideEffect(context, target, "uptime", Uptime);
-  SetMethod(context, target, "patchProcessObject", PatchProcessObject);
+  SetMethod(isolate, target, "_debugProcess", DebugProcess);
+  SetMethod(isolate, target, "abort", Abort);
+  SetMethod(isolate, target, "causeSegfault", CauseSegfault);
+  SetMethod(isolate, target, "chdir", Chdir);
+
+  SetMethod(isolate, target, "umask", Umask);
+  SetMethod(isolate, target, "memoryUsage", MemoryUsage);
+  SetMethod(isolate, target, "constrainedMemory", GetConstrainedMemory);
+  SetMethod(isolate, target, "rss", Rss);
+  SetMethod(isolate, target, "cpuUsage", CPUUsage);
+  SetMethod(isolate, target, "resourceUsage", ResourceUsage);
+
+  SetMethod(isolate, target, "_debugEnd", DebugEnd);
+  SetMethod(isolate, target, "_getActiveRequests", GetActiveRequests);
+  SetMethod(isolate, target, "_getActiveHandles", GetActiveHandles);
+  SetMethod(isolate, target, "getActiveResourcesInfo", GetActiveResourcesInfo);
+  SetMethod(isolate, target, "_kill", Kill);
+  SetMethod(isolate, target, "_rawDebug", RawDebug);
+
+  SetMethodNoSideEffect(isolate, target, "cwd", Cwd);
+  SetMethod(isolate, target, "dlopen", binding::DLOpen);
+  SetMethod(isolate, target, "reallyExit", ReallyExit);
+  SetMethodNoSideEffect(isolate, target, "uptime", Uptime);
+  SetMethod(isolate, target, "patchProcessObject", PatchProcessObject);
+}
+
+static void CreatePerContextProperties(Local<Object> target,
+                                       Local<Value> unused,
+                                       Local<Context> context,
+                                       void* priv) {
+  Realm* realm = Realm::GetCurrent(context);
+  realm->AddBindingData<BindingData>(context, target);
 }
 
 void RegisterExternalReferences(ExternalReferenceRegistry* registry) {
@@ -641,6 +644,9 @@ void RegisterExternalReferences(ExternalReferenceRegistry* registry) {
 }  // namespace process
 }  // namespace node
 
-NODE_BINDING_CONTEXT_AWARE_INTERNAL(process_methods, node::process::Initialize)
+NODE_BINDING_CONTEXT_AWARE_INTERNAL(process_methods,
+                                    node::process::CreatePerContextProperties)
+NODE_BINDING_PER_ISOLATE_INIT(process_methods,
+                              node::process::CreatePerIsolateProperties)
 NODE_BINDING_EXTERNAL_REFERENCE(process_methods,
                                 node::process::RegisterExternalReferences)
diff --git a/src/node_stat_watcher.cc b/src/node_stat_watcher.cc
index 83b96e9dd2030e..39a22eb2e1fca5 100644
--- a/src/node_stat_watcher.cc
+++ b/src/node_stat_watcher.cc
@@ -40,21 +40,22 @@ using v8::Integer;
 using v8::Isolate;
 using v8::Local;
 using v8::Object;
+using v8::ObjectTemplate;
 using v8::Uint32;
 using v8::Value;
 
-void StatWatcher::Initialize(Environment* env, Local<Object> target) {
-  Isolate* isolate = env->isolate();
-  HandleScope scope(env->isolate());
+void StatWatcher::CreatePerIsolateProperties(IsolateData* isolate_data,
+                                             Local<FunctionTemplate> ctor) {
+  Isolate* isolate = isolate_data->isolate();
+  Local<ObjectTemplate> target = ctor->InstanceTemplate();
 
   Local<FunctionTemplate> t = NewFunctionTemplate(isolate, StatWatcher::New);
   t->InstanceTemplate()->SetInternalFieldCount(
       StatWatcher::kInternalFieldCount);
-  t->Inherit(HandleWrap::GetConstructorTemplate(env));
-
+  t->Inherit(HandleWrap::GetConstructorTemplate(isolate_data));
   SetProtoMethod(isolate, t, "start", StatWatcher::Start);
 
-  SetConstructorFunction(env->context(), target, "StatWatcher", t);
+  SetConstructorFunction(isolate, target, "StatWatcher", t);
 }
 
 void StatWatcher::RegisterExternalReferences(
diff --git a/src/node_stat_watcher.h b/src/node_stat_watcher.h
index 7efd22fdfdb841..cc76975ddb5653 100644
--- a/src/node_stat_watcher.h
+++ b/src/node_stat_watcher.h
@@ -39,7 +39,8 @@ class ExternalReferenceRegistry;
 
 class StatWatcher : public HandleWrap {
  public:
-  static void Initialize(Environment* env, v8::Local<v8::Object> target);
+  static void CreatePerIsolateProperties(IsolateData* isolate_data,
+                                         v8::Local<v8::FunctionTemplate> ctor);
   static void RegisterExternalReferences(ExternalReferenceRegistry* registry);
 
  protected:
diff --git a/src/node_url.cc b/src/node_url.cc
index 02f9e580971796..078e155fc49374 100644
--- a/src/node_url.cc
+++ b/src/node_url.cc
@@ -19,11 +19,13 @@ using v8::CFunction;
 using v8::Context;
 using v8::FastOneByteString;
 using v8::FunctionCallbackInfo;
+using v8::FunctionTemplate;
 using v8::HandleScope;
 using v8::Isolate;
 using v8::Local;
 using v8::NewStringType;
 using v8::Object;
+using v8::ObjectTemplate;
 using v8::String;
 using v8::Value;
 
@@ -322,22 +324,25 @@ void BindingData::UpdateComponents(const ada::url_components& components,
                 "kURLComponentsLength should be up-to-date");
 }
 
-void BindingData::Initialize(Local<Object> target,
-                             Local<Value> unused,
-                             Local<Context> context,
-                             void* priv) {
-  Realm* realm = Realm::GetCurrent(context);
-  BindingData* const binding_data =
-      realm->AddBindingData<BindingData>(context, target);
-  if (binding_data == nullptr) return;
-
-  SetMethodNoSideEffect(context, target, "domainToASCII", DomainToASCII);
-  SetMethodNoSideEffect(context, target, "domainToUnicode", DomainToUnicode);
-  SetMethodNoSideEffect(context, target, "format", Format);
-  SetMethod(context, target, "parse", Parse);
-  SetMethod(context, target, "update", Update);
+void BindingData::CreatePerIsolateProperties(IsolateData* isolate_data,
+                                             Local<FunctionTemplate> ctor) {
+  Isolate* isolate = isolate_data->isolate();
+  Local<ObjectTemplate> target = ctor->InstanceTemplate();
+  SetMethodNoSideEffect(isolate, target, "domainToASCII", DomainToASCII);
+  SetMethodNoSideEffect(isolate, target, "domainToUnicode", DomainToUnicode);
+  SetMethodNoSideEffect(isolate, target, "format", Format);
+  SetMethod(isolate, target, "parse", Parse);
+  SetMethod(isolate, target, "update", Update);
   SetFastMethodNoSideEffect(
-      context, target, "canParse", CanParse, &fast_can_parse_);
+      isolate, target, "canParse", CanParse, &fast_can_parse_);
+}
+
+void BindingData::CreatePerContextProperties(Local<Object> target,
+                                             Local<Value> unused,
+                                             Local<Context> context,
+                                             void* priv) {
+  Realm* realm = Realm::GetCurrent(context);
+  realm->AddBindingData<BindingData>(context, target);
 }
 
 void BindingData::RegisterExternalReferences(
@@ -365,6 +370,9 @@ std::string FromFilePath(const std::string_view file_path) {
 
 }  // namespace node
 
-NODE_BINDING_CONTEXT_AWARE_INTERNAL(url, node::url::BindingData::Initialize)
+NODE_BINDING_CONTEXT_AWARE_INTERNAL(
+    url, node::url::BindingData::CreatePerContextProperties)
+NODE_BINDING_PER_ISOLATE_INIT(
+    url, node::url::BindingData::CreatePerIsolateProperties)
 NODE_BINDING_EXTERNAL_REFERENCE(
     url, node::url::BindingData::RegisterExternalReferences)
diff --git a/src/node_url.h b/src/node_url.h
index 735a191e5eac16..04a57a9e2c413a 100644
--- a/src/node_url.h
+++ b/src/node_url.h
@@ -56,10 +56,12 @@ class BindingData : public SnapshotableObject {
   static void Parse(const v8::FunctionCallbackInfo<v8::Value>& args);
   static void Update(const v8::FunctionCallbackInfo<v8::Value>& args);
 
-  static void Initialize(v8::Local<v8::Object> target,
-                         v8::Local<v8::Value> unused,
-                         v8::Local<v8::Context> context,
-                         void* priv);
+  static void CreatePerIsolateProperties(IsolateData* isolate_data,
+                                         v8::Local<v8::FunctionTemplate> ctor);
+  static void CreatePerContextProperties(v8::Local<v8::Object> target,
+                                         v8::Local<v8::Value> unused,
+                                         v8::Local<v8::Context> context,
+                                         void* priv);
   static void RegisterExternalReferences(ExternalReferenceRegistry* registry);
 
  private:
diff --git a/src/stream_base.cc b/src/stream_base.cc
index f1769ca52970fe..65dab1ccac7cde 100644
--- a/src/stream_base.cc
+++ b/src/stream_base.cc
@@ -491,13 +491,12 @@ Local<Object> StreamBase::GetObject() {
   return GetAsyncWrap()->object();
 }
 
-void StreamBase::AddMethod(Environment* env,
+void StreamBase::AddMethod(Isolate* isolate,
                            Local<Signature> signature,
                            enum PropertyAttribute attributes,
                            Local<FunctionTemplate> t,
                            JSMethodFunction* stream_method,
                            Local<String> string) {
-  Isolate* isolate = env->isolate();
   Local<FunctionTemplate> templ =
       NewFunctionTemplate(isolate,
                           stream_method,
@@ -509,19 +508,37 @@ void StreamBase::AddMethod(Environment* env,
 }
 
 void StreamBase::AddMethods(Environment* env, Local<FunctionTemplate> t) {
-  Isolate* isolate = env->isolate();
+  AddMethods(env->isolate_data(), t);
+}
+
+void StreamBase::AddMethods(IsolateData* isolate_data,
+                            Local<FunctionTemplate> t) {
+  Isolate* isolate = isolate_data->isolate();
   HandleScope scope(isolate);
 
   enum PropertyAttribute attributes =
       static_cast<PropertyAttribute>(ReadOnly | DontDelete | DontEnum);
   Local<Signature> sig = Signature::New(isolate, t);
 
-  AddMethod(env, sig, attributes, t, GetFD, env->fd_string());
-  AddMethod(
-      env, sig, attributes, t, GetExternal, env->external_stream_string());
-  AddMethod(env, sig, attributes, t, GetBytesRead, env->bytes_read_string());
-  AddMethod(
-      env, sig, attributes, t, GetBytesWritten, env->bytes_written_string());
+  AddMethod(isolate, sig, attributes, t, GetFD, isolate_data->fd_string());
+  AddMethod(isolate,
+            sig,
+            attributes,
+            t,
+            GetExternal,
+            isolate_data->external_stream_string());
+  AddMethod(isolate,
+            sig,
+            attributes,
+            t,
+            GetBytesRead,
+            isolate_data->bytes_read_string());
+  AddMethod(isolate,
+            sig,
+            attributes,
+            t,
+            GetBytesWritten,
+            isolate_data->bytes_written_string());
   SetProtoMethod(isolate, t, "readStart", JSMethod<&StreamBase::ReadStartJS>);
   SetProtoMethod(isolate, t, "readStop", JSMethod<&StreamBase::ReadStopJS>);
   SetProtoMethod(isolate, t, "shutdown", JSMethod<&StreamBase::Shutdown>);
diff --git a/src/stream_base.h b/src/stream_base.h
index 3035ae89715518..e96ff036157ab9 100644
--- a/src/stream_base.h
+++ b/src/stream_base.h
@@ -313,6 +313,8 @@ class StreamBase : public StreamResource {
     kInternalFieldCount
   };
 
+  static void AddMethods(IsolateData* isolate_data,
+                         v8::Local<v8::FunctionTemplate> target);
   static void AddMethods(Environment* env,
                          v8::Local<v8::FunctionTemplate> target);
   static void RegisterExternalReferences(ExternalReferenceRegistry* registry);
@@ -409,7 +411,7 @@ class StreamBase : public StreamResource {
   EmitToJSStreamListener default_listener_;
 
   void SetWriteResult(const StreamWriteResult& res);
-  static void AddMethod(Environment* env,
+  static void AddMethod(v8::Isolate* isolate,
                         v8::Local<v8::Signature> sig,
                         enum v8::PropertyAttribute attributes,
                         v8::Local<v8::FunctionTemplate> t,
diff --git a/src/timers.cc b/src/timers.cc
index 2f10daba12ef3a..8318894e33cb54 100644
--- a/src/timers.cc
+++ b/src/timers.cc
@@ -12,9 +12,12 @@ namespace timers {
 using v8::Context;
 using v8::Function;
 using v8::FunctionCallbackInfo;
+using v8::FunctionTemplate;
+using v8::Isolate;
 using v8::Local;
 using v8::Number;
 using v8::Object;
+using v8::ObjectTemplate;
 using v8::Value;
 
 void BindingData::SetupTimers(const FunctionCallbackInfo<Value>& args) {
@@ -119,34 +122,40 @@ v8::CFunction BindingData::fast_toggle_timer_ref_(
 v8::CFunction BindingData::fast_toggle_immediate_ref_(
     v8::CFunction::Make(FastToggleImmediateRef));
 
-void BindingData::Initialize(Local<Object> target,
-                             Local<Value> unused,
-                             Local<Context> context,
-                             void* priv) {
-  Realm* realm = Realm::GetCurrent(context);
-  Environment* env = realm->env();
-  BindingData* const binding_data =
-      realm->AddBindingData<BindingData>(context, target);
-  if (binding_data == nullptr) return;
+void BindingData::CreatePerIsolateProperties(IsolateData* isolate_data,
+                                             Local<FunctionTemplate> ctor) {
+  Isolate* isolate = isolate_data->isolate();
+  Local<ObjectTemplate> target = ctor->InstanceTemplate();
 
-  SetMethod(context, target, "setupTimers", SetupTimers);
+  SetMethod(isolate, target, "setupTimers", SetupTimers);
   SetFastMethod(
-      context, target, "getLibuvNow", SlowGetLibuvNow, &fast_get_libuv_now_);
-  SetFastMethod(context,
+      isolate, target, "getLibuvNow", SlowGetLibuvNow, &fast_get_libuv_now_);
+  SetFastMethod(isolate,
                 target,
                 "scheduleTimer",
                 SlowScheduleTimer,
                 &fast_schedule_timers_);
-  SetFastMethod(context,
+  SetFastMethod(isolate,
                 target,
                 "toggleTimerRef",
                 SlowToggleTimerRef,
                 &fast_toggle_timer_ref_);
-  SetFastMethod(context,
+  SetFastMethod(isolate,
                 target,
                 "toggleImmediateRef",
                 SlowToggleImmediateRef,
                 &fast_toggle_immediate_ref_);
+}
+
+void BindingData::CreatePerContextProperties(Local<Object> target,
+                                             Local<Value> unused,
+                                             Local<Context> context,
+                                             void* priv) {
+  Realm* realm = Realm::GetCurrent(context);
+  Environment* env = realm->env();
+  BindingData* const binding_data =
+      realm->AddBindingData<BindingData>(context, target);
+  if (binding_data == nullptr) return;
 
   // TODO(joyeecheung): move these into BindingData.
   target
@@ -187,7 +196,9 @@ void BindingData::RegisterTimerExternalReferences(
 
 }  // namespace node
 
-NODE_BINDING_CONTEXT_AWARE_INTERNAL(timers,
-                                    node::timers::BindingData::Initialize)
+NODE_BINDING_CONTEXT_AWARE_INTERNAL(
+    timers, node::timers::BindingData::CreatePerContextProperties)
+NODE_BINDING_PER_ISOLATE_INIT(
+    timers, node::timers::BindingData::CreatePerIsolateProperties)
 NODE_BINDING_EXTERNAL_REFERENCE(
     timers, node::timers::BindingData::RegisterTimerExternalReferences)
diff --git a/src/timers.h b/src/timers.h
index 7f2ac45e71af6d..61cc5d6bf8ed43 100644
--- a/src/timers.h
+++ b/src/timers.h
@@ -45,10 +45,12 @@ class BindingData : public SnapshotableObject {
   static void FastToggleImmediateRef(v8::Local<v8::Object> receiver, bool ref);
   static void ToggleImmediateRefImpl(BindingData* data, bool ref);
 
-  static void Initialize(v8::Local<v8::Object> target,
-                         v8::Local<v8::Value> unused,
-                         v8::Local<v8::Context> context,
-                         void* priv);
+  static void CreatePerIsolateProperties(IsolateData* isolate_data,
+                                         v8::Local<v8::FunctionTemplate> ctor);
+  static void CreatePerContextProperties(v8::Local<v8::Object> target,
+                                         v8::Local<v8::Value> unused,
+                                         v8::Local<v8::Context> context,
+                                         void* priv);
   static void RegisterTimerExternalReferences(
       ExternalReferenceRegistry* registry);