diff --git a/instrumentation/classloaders/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/javaclassloader/ClassLoaderInstrumentation.java b/instrumentation/classloaders/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/javaclassloader/ClassLoaderInstrumentation.java
index 33c4175ffdfa..6e1fceabf011 100644
--- a/instrumentation/classloaders/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/javaclassloader/ClassLoaderInstrumentation.java
+++ b/instrumentation/classloaders/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/javaclassloader/ClassLoaderInstrumentation.java
@@ -62,11 +62,11 @@ public Map<? extends ElementMatcher<? super MethodDescription>, String> transfor
             .and(named("loadClass"))
             .and(
                 takesArguments(1)
-                    .and(takesArgument(0, named("java.lang.String")))
+                    .and(takesArgument(0, String.class))
                     .or(
                         takesArguments(2)
-                            .and(takesArgument(0, named("java.lang.String")))
-                            .and(takesArgument(1, named("boolean")))))
+                            .and(takesArgument(0, String.class))
+                            .and(takesArgument(1, boolean.class))))
             .and(isPublic().or(isProtected()))
             .and(not(isStatic())),
         ClassLoaderInstrumentation.class.getName() + "$LoadClassAdvice");
diff --git a/instrumentation/couchbase/couchbase-2.6/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/couchbase/v2_6/CouchbaseNetworkInstrumentation.java b/instrumentation/couchbase/couchbase-2.6/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/couchbase/v2_6/CouchbaseNetworkInstrumentation.java
index 1fdd4b1529f5..3e53c5b03e5f 100644
--- a/instrumentation/couchbase/couchbase-2.6/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/couchbase/v2_6/CouchbaseNetworkInstrumentation.java
+++ b/instrumentation/couchbase/couchbase-2.6/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/couchbase/v2_6/CouchbaseNetworkInstrumentation.java
@@ -21,6 +21,7 @@
 import io.opentelemetry.javaagent.instrumentation.api.InstrumentationContext;
 import io.opentelemetry.javaagent.tooling.TypeInstrumentation;
 import io.opentelemetry.semconv.trace.attributes.SemanticAttributes;
+import java.util.List;
 import java.util.Map;
 import net.bytebuddy.asm.Advice;
 import net.bytebuddy.description.method.MethodDescription;
@@ -52,7 +53,7 @@ public Map<? extends ElementMatcher<? super MethodDescription>, String> transfor
             .and(
                 takesArgument(
                     0, named("com.couchbase.client.deps.io.netty.channel.ChannelHandlerContext")))
-            .and(takesArgument(2, named("java.util.List"))),
+            .and(takesArgument(2, List.class)),
         CouchbaseNetworkInstrumentation.class.getName() + "$CouchbaseNetworkAdvice");
   }
 
diff --git a/instrumentation/elasticsearch/elasticsearch-rest-5.0/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/elasticsearch/rest/v5_0/Elasticsearch5RestClientInstrumentationModule.java b/instrumentation/elasticsearch/elasticsearch-rest-5.0/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/elasticsearch/rest/v5_0/Elasticsearch5RestClientInstrumentationModule.java
index 9b274430f5b9..9c358774db85 100644
--- a/instrumentation/elasticsearch/elasticsearch-rest-5.0/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/elasticsearch/rest/v5_0/Elasticsearch5RestClientInstrumentationModule.java
+++ b/instrumentation/elasticsearch/elasticsearch-rest-5.0/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/elasticsearch/rest/v5_0/Elasticsearch5RestClientInstrumentationModule.java
@@ -52,8 +52,8 @@ public Map<? extends ElementMatcher<? super MethodDescription>, String> transfor
           isMethod()
               .and(namedOneOf("performRequestAsync", "performRequestAsyncNoCatch"))
               .and(takesArguments(7))
-              .and(takesArgument(0, named("java.lang.String"))) // method
-              .and(takesArgument(1, named("java.lang.String"))) // endpoint
+              .and(takesArgument(0, String.class)) // method
+              .and(takesArgument(1, String.class)) // endpoint
               .and(takesArgument(5, named("org.elasticsearch.client.ResponseListener"))),
           Elasticsearch5RestClientInstrumentationModule.class.getName()
               + "$ElasticsearchRestClientAdvice");
diff --git a/instrumentation/geode-1.4/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/geode/GeodeInstrumentationModule.java b/instrumentation/geode-1.4/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/geode/GeodeInstrumentationModule.java
index 8bbebaa42ad4..3867d9dc05db 100644
--- a/instrumentation/geode-1.4/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/geode/GeodeInstrumentationModule.java
+++ b/instrumentation/geode-1.4/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/geode/GeodeInstrumentationModule.java
@@ -74,7 +74,7 @@ public Map<? extends ElementMatcher<? super MethodDescription>, String> transfor
       map.put(
           isMethod()
               .and(named("existsValue").or(named("query")).or(named("selectValue")))
-              .and(takesArgument(0, named("java.lang.String"))),
+              .and(takesArgument(0, String.class)),
           GeodeInstrumentationModule.class.getName() + "$QueryAdvice");
       return map;
     }
diff --git a/instrumentation/google-http-client-1.19/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/googlehttpclient/GoogleHttpClientInstrumentationModule.java b/instrumentation/google-http-client-1.19/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/googlehttpclient/GoogleHttpClientInstrumentationModule.java
index 762c6843476c..acd894d7f81d 100644
--- a/instrumentation/google-http-client-1.19/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/googlehttpclient/GoogleHttpClientInstrumentationModule.java
+++ b/instrumentation/google-http-client-1.19/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/googlehttpclient/GoogleHttpClientInstrumentationModule.java
@@ -26,6 +26,7 @@
 import java.util.HashMap;
 import java.util.List;
 import java.util.Map;
+import java.util.concurrent.Executor;
 import net.bytebuddy.asm.Advice;
 import net.bytebuddy.description.method.MethodDescription;
 import net.bytebuddy.description.type.TypeDescription;
@@ -68,7 +69,7 @@ public Map<? extends ElementMatcher<? super MethodDescription>, String> transfor
               .and(isPublic())
               .and(named("executeAsync"))
               .and(takesArguments(1))
-              .and(takesArgument(0, (named("java.util.concurrent.Executor")))),
+              .and(takesArgument(0, Executor.class)),
           GoogleHttpClientInstrumentationModule.class.getName() + "$GoogleHttpClientAsyncAdvice");
 
       return transformers;
diff --git a/instrumentation/grizzly-2.0/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/grizzly/DefaultFilterChainInstrumentation.java b/instrumentation/grizzly-2.0/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/grizzly/DefaultFilterChainInstrumentation.java
index 356ad2b00af4..ebc19cec6b6f 100644
--- a/instrumentation/grizzly-2.0/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/grizzly/DefaultFilterChainInstrumentation.java
+++ b/instrumentation/grizzly-2.0/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/grizzly/DefaultFilterChainInstrumentation.java
@@ -31,7 +31,7 @@ public Map<? extends ElementMatcher<? super MethodDescription>, String> transfor
             .and(isPrivate())
             .and(named("notifyFailure"))
             .and(takesArgument(0, named("org.glassfish.grizzly.filterchain.FilterChainContext")))
-            .and(takesArgument(1, named("java.lang.Throwable"))),
+            .and(takesArgument(1, Throwable.class)),
         DefaultFilterChainAdvice.class.getName());
   }
 }
diff --git a/instrumentation/hibernate/hibernate-3.3/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/hibernate/v3_3/SessionInstrumentation.java b/instrumentation/hibernate/hibernate-3.3/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/hibernate/v3_3/SessionInstrumentation.java
index 89cba7d1cab3..78e83693e9cf 100644
--- a/instrumentation/hibernate/hibernate-3.3/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/hibernate/v3_3/SessionInstrumentation.java
+++ b/instrumentation/hibernate/hibernate-3.3/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/hibernate/v3_3/SessionInstrumentation.java
@@ -79,10 +79,7 @@ public Map<? extends ElementMatcher<? super MethodDescription>, String> transfor
 
     // Handle the non-generic 'get' separately.
     transformers.put(
-        isMethod()
-            .and(named("get"))
-            .and(returns(named("java.lang.Object")))
-            .and(takesArgument(0, named("java.lang.String"))),
+        isMethod().and(named("get")).and(returns(Object.class)).and(takesArgument(0, String.class)),
         SessionInstrumentation.class.getName() + "$SessionMethodAdvice");
 
     // These methods return some object that we want to instrument, and so the Advice will pin the
diff --git a/instrumentation/hibernate/hibernate-4.0/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/hibernate/v4_0/SessionInstrumentation.java b/instrumentation/hibernate/hibernate-4.0/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/hibernate/v4_0/SessionInstrumentation.java
index e396e383a8b2..88063c74e731 100644
--- a/instrumentation/hibernate/hibernate-4.0/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/hibernate/v4_0/SessionInstrumentation.java
+++ b/instrumentation/hibernate/hibernate-4.0/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/hibernate/v4_0/SessionInstrumentation.java
@@ -76,10 +76,7 @@ public Map<? extends ElementMatcher<? super MethodDescription>, String> transfor
         SessionInstrumentation.class.getName() + "$SessionMethodAdvice");
     // Handle the non-generic 'get' separately.
     transformers.put(
-        isMethod()
-            .and(named("get"))
-            .and(returns(named("java.lang.Object")))
-            .and(takesArgument(0, named("java.lang.String"))),
+        isMethod().and(named("get")).and(returns(Object.class)).and(takesArgument(0, String.class)),
         SessionInstrumentation.class.getName() + "$SessionMethodAdvice");
 
     // These methods return some object that we want to instrument, and so the Advice will pin the
diff --git a/instrumentation/jetty-8.0/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/jetty/JettyInstrumentationModule.java b/instrumentation/jetty-8.0/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/jetty/JettyInstrumentationModule.java
index e683a8fa3fd0..51ceae3d2dee 100644
--- a/instrumentation/jetty-8.0/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/jetty/JettyInstrumentationModule.java
+++ b/instrumentation/jetty-8.0/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/jetty/JettyInstrumentationModule.java
@@ -63,7 +63,7 @@ public ElementMatcher<TypeDescription> typeMatcher() {
     public Map<? extends ElementMatcher<? super MethodDescription>, String> transformers() {
       return singletonMap(
           named("handle")
-              .and(takesArgument(0, named("java.lang.String")))
+              .and(takesArgument(0, String.class))
               .and(takesArgument(1, named("org.eclipse.jetty.server.Request")))
               .and(takesArgument(2, named("javax.servlet.http.HttpServletRequest")))
               .and(takesArgument(3, named("javax.servlet.http.HttpServletResponse")))
diff --git a/instrumentation/khttp-0.1/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/khttp/KHttpInstrumentationModule.java b/instrumentation/khttp-0.1/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/khttp/KHttpInstrumentationModule.java
index 6364e37bdf9f..3741b9e25796 100644
--- a/instrumentation/khttp-0.1/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/khttp/KHttpInstrumentationModule.java
+++ b/instrumentation/khttp-0.1/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/khttp/KHttpInstrumentationModule.java
@@ -54,9 +54,9 @@ public Map<? extends ElementMatcher<? super MethodDescription>, String> transfor
           isMethod()
               .and(not(isAbstract()))
               .and(named("request"))
-              .and(takesArgument(0, named("java.lang.String")))
-              .and(takesArgument(1, named("java.lang.String")))
-              .and(takesArgument(2, named("java.util.Map")))
+              .and(takesArgument(0, String.class))
+              .and(takesArgument(1, String.class))
+              .and(takesArgument(2, Map.class))
               .and(returns(named("khttp.responses.Response"))),
           KHttpAdvice.class.getName());
     }
diff --git a/instrumentation/lettuce/lettuce-5.0/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/lettuce/v5_0/LettuceReactiveCommandsInstrumentation.java b/instrumentation/lettuce/lettuce-5.0/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/lettuce/v5_0/LettuceReactiveCommandsInstrumentation.java
index 65e8836c0cd2..d04aa57ef45c 100644
--- a/instrumentation/lettuce/lettuce-5.0/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/lettuce/v5_0/LettuceReactiveCommandsInstrumentation.java
+++ b/instrumentation/lettuce/lettuce-5.0/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/lettuce/v5_0/LettuceReactiveCommandsInstrumentation.java
@@ -18,6 +18,7 @@
 import io.opentelemetry.javaagent.tooling.TypeInstrumentation;
 import java.util.HashMap;
 import java.util.Map;
+import java.util.function.Supplier;
 import net.bytebuddy.description.method.MethodDescription;
 import net.bytebuddy.description.type.TypeDescription;
 import net.bytebuddy.matcher.ElementMatcher;
@@ -35,7 +36,7 @@ public Map<? extends ElementMatcher<? super MethodDescription>, String> transfor
     transformers.put(
         isMethod()
             .and(named("createMono"))
-            .and(takesArgument(0, named("java.util.function.Supplier")))
+            .and(takesArgument(0, Supplier.class))
             .and(returns(named("reactor.core.publisher.Mono"))),
         LettuceMonoCreationAdvice.class.getName());
     transformers.put(
@@ -43,7 +44,7 @@ public Map<? extends ElementMatcher<? super MethodDescription>, String> transfor
             .and(nameStartsWith("create"))
             .and(nameEndsWith("Flux"))
             .and(isPublic())
-            .and(takesArgument(0, named("java.util.function.Supplier")))
+            .and(takesArgument(0, Supplier.class))
             .and(returns(named("reactor.core.publisher.Flux"))),
         LettuceFluxCreationAdvice.class.getName());
 
diff --git a/instrumentation/rmi/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/rmi/client/RmiClientInstrumentationModule.java b/instrumentation/rmi/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/rmi/client/RmiClientInstrumentationModule.java
index aafa55ffdf24..36c450f4da9b 100644
--- a/instrumentation/rmi/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/rmi/client/RmiClientInstrumentationModule.java
+++ b/instrumentation/rmi/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/rmi/client/RmiClientInstrumentationModule.java
@@ -51,7 +51,7 @@ public Map<? extends ElementMatcher<? super MethodDescription>, String> transfor
           isMethod()
               .and(named("invoke"))
               .and(takesArgument(0, named("java.rmi.Remote")))
-              .and(takesArgument(1, named("java.lang.reflect.Method"))),
+              .and(takesArgument(1, Method.class)),
           RmiClientInstrumentationModule.class.getName() + "$RmiClientAdvice");
     }
   }
diff --git a/instrumentation/spring/spring-webflux-5.0/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/spring/webflux/server/HandlerAdapterInstrumentation.java b/instrumentation/spring/spring-webflux-5.0/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/spring/webflux/server/HandlerAdapterInstrumentation.java
index 5f92190bceae..49d9afa71e19 100644
--- a/instrumentation/spring/spring-webflux-5.0/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/spring/webflux/server/HandlerAdapterInstrumentation.java
+++ b/instrumentation/spring/spring-webflux-5.0/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/spring/webflux/server/HandlerAdapterInstrumentation.java
@@ -42,7 +42,7 @@ public Map<? extends ElementMatcher<? super MethodDescription>, String> transfor
             .and(isPublic())
             .and(named("handle"))
             .and(takesArgument(0, named("org.springframework.web.server.ServerWebExchange")))
-            .and(takesArgument(1, named("java.lang.Object")))
+            .and(takesArgument(1, Object.class))
             .and(takesArguments(2)),
         HandlerAdapterAdvice.class.getName());
   }
diff --git a/instrumentation/vertx-reactive-3.5/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/vertx/reactive/VertxRxInstrumentationModule.java b/instrumentation/vertx-reactive-3.5/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/vertx/reactive/VertxRxInstrumentationModule.java
index 79b2d3bf28b6..fb3662163a4e 100644
--- a/instrumentation/vertx-reactive-3.5/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/vertx/reactive/VertxRxInstrumentationModule.java
+++ b/instrumentation/vertx-reactive-3.5/javaagent/src/main/java/io/opentelemetry/javaagent/instrumentation/vertx/reactive/VertxRxInstrumentationModule.java
@@ -60,7 +60,7 @@ public Map<? extends ElementMatcher<? super MethodDescription>, String> transfor
           isConstructor().and(takesArgument(0, named("io.vertx.core.Handler"))),
           VertxRxInstrumentationModule.class.getName() + "$AsyncResultSingleHandlerAdvice");
       result.put(
-          isConstructor().and(takesArgument(0, named("java.util.function.Consumer"))),
+          isConstructor().and(takesArgument(0, Consumer.class)),
           VertxRxInstrumentationModule.class.getName() + "$AsyncResultSingleConsumerAdvice");
       return result;
     }