diff --git a/async_substrate_interface/async_substrate.py b/async_substrate_interface/async_substrate.py
index 612670c..502b743 100644
--- a/async_substrate_interface/async_substrate.py
+++ b/async_substrate_interface/async_substrate.py
@@ -49,6 +49,7 @@
     Preprocessed,
 )
 from async_substrate_interface.utils import hex_to_bytes, json, get_next_id
+from async_substrate_interface.utils.cache import async_sql_lru_cache
 from async_substrate_interface.utils.decoding import (
     _determine_if_old_runtime_call,
     _bt_decode_to_dict_or_list,
@@ -1659,8 +1660,11 @@ def convert_event_data(data):
                 events.append(convert_event_data(item))
         return events
 
-    @a.lru_cache(maxsize=512)  # large cache with small items
+    @a.lru_cache(maxsize=512)
     async def get_parent_block_hash(self, block_hash):
+        return await self._get_parent_block_hash(block_hash)
+
+    async def _get_parent_block_hash(self, block_hash):
         block_header = await self.rpc_request("chain_getHeader", [block_hash])
 
         if block_header["result"] is None:
@@ -1672,16 +1676,22 @@ async def get_parent_block_hash(self, block_hash):
             return block_hash
         return parent_block_hash
 
-    @a.lru_cache(maxsize=16)  # small cache with large items
+    @a.lru_cache(maxsize=16)
     async def get_block_runtime_info(self, block_hash: str) -> dict:
+        return await self._get_block_runtime_info(block_hash)
+
+    async def _get_block_runtime_info(self, block_hash: str) -> dict:
         """
         Retrieve the runtime info of given block_hash
         """
         response = await self.rpc_request("state_getRuntimeVersion", [block_hash])
         return response.get("result")
 
-    @a.lru_cache(maxsize=512)  # large cache with small items
+    @a.lru_cache(maxsize=512)
     async def get_block_runtime_version_for(self, block_hash: str):
+        return await self._get_block_runtime_version_for(block_hash)
+
+    async def _get_block_runtime_version_for(self, block_hash: str):
         """
         Retrieve the runtime version of the parent of a given block_hash
         """
@@ -1914,7 +1924,6 @@ async def _make_rpc_request(
 
         return request_manager.get_results()
 
-    @a.lru_cache(maxsize=512)  # RPC methods are unlikely to change often
     async def supports_rpc_method(self, name: str) -> bool:
         """
         Check if substrate RPC supports given method
@@ -1985,8 +1994,11 @@ async def rpc_request(
         else:
             raise SubstrateRequestException(result[payload_id][0])
 
-    @a.lru_cache(maxsize=512)  # block_id->block_hash does not change
+    @a.lru_cache(maxsize=512)
     async def get_block_hash(self, block_id: int) -> str:
+        return await self._get_block_hash(block_id)
+
+    async def _get_block_hash(self, block_id: int) -> str:
         return (await self.rpc_request("chain_getBlockHash", [block_id]))["result"]
 
     async def get_chain_head(self) -> str:
@@ -3230,6 +3242,28 @@ async def _handler(block_data: dict[str, Any]):
             return await co
 
 
+class DiskCachedAsyncSubstrateInterface(AsyncSubstrateInterface):
+    """
+    Experimental new class that uses disk-caching in addition to memory-caching for the cached methods
+    """
+
+    @async_sql_lru_cache(maxsize=512)
+    async def get_parent_block_hash(self, block_hash):
+        return await self._get_parent_block_hash(block_hash)
+
+    @async_sql_lru_cache(maxsize=16)
+    async def get_block_runtime_info(self, block_hash: str) -> dict:
+        return await self._get_block_runtime_info(block_hash)
+
+    @async_sql_lru_cache(maxsize=512)
+    async def get_block_runtime_version_for(self, block_hash: str):
+        return await self._get_block_runtime_version_for(block_hash)
+
+    @async_sql_lru_cache(maxsize=512)
+    async def get_block_hash(self, block_id: int) -> str:
+        return await self._get_block_hash(block_id)
+
+
 async def get_async_substrate_interface(
     url: str,
     use_remote_preset: bool = False,
diff --git a/async_substrate_interface/sync_substrate.py b/async_substrate_interface/sync_substrate.py
index d327687..daad7ce 100644
--- a/async_substrate_interface/sync_substrate.py
+++ b/async_substrate_interface/sync_substrate.py
@@ -1,6 +1,6 @@
+import functools
 import logging
 import random
-from functools import lru_cache
 from hashlib import blake2b
 from typing import Optional, Union, Callable, Any
 
@@ -1406,7 +1406,7 @@ def convert_event_data(data):
                 events.append(convert_event_data(item))
         return events
 
-    @lru_cache(maxsize=512)  # large cache with small items
+    @functools.lru_cache(maxsize=512)
     def get_parent_block_hash(self, block_hash):
         block_header = self.rpc_request("chain_getHeader", [block_hash])
 
@@ -1419,7 +1419,7 @@ def get_parent_block_hash(self, block_hash):
             return block_hash
         return parent_block_hash
 
-    @lru_cache(maxsize=16)  # small cache with large items
+    @functools.lru_cache(maxsize=16)
     def get_block_runtime_info(self, block_hash: str) -> dict:
         """
         Retrieve the runtime info of given block_hash
@@ -1427,7 +1427,7 @@ def get_block_runtime_info(self, block_hash: str) -> dict:
         response = self.rpc_request("state_getRuntimeVersion", [block_hash])
         return response.get("result")
 
-    @lru_cache(maxsize=512)  # large cache with small items
+    @functools.lru_cache(maxsize=512)
     def get_block_runtime_version_for(self, block_hash: str):
         """
         Retrieve the runtime version of the parent of a given block_hash
@@ -1655,8 +1655,7 @@ def _make_rpc_request(
 
         return request_manager.get_results()
 
-    # TODO change this logic
-    @lru_cache(maxsize=512)  # RPC methods are unlikely to change often
+    @functools.lru_cache(maxsize=512)
     def supports_rpc_method(self, name: str) -> bool:
         """
         Check if substrate RPC supports given method
@@ -1727,7 +1726,7 @@ def rpc_request(
         else:
             raise SubstrateRequestException(result[payload_id][0])
 
-    @lru_cache(maxsize=512)  # block_id->block_hash does not change
+    @functools.lru_cache(maxsize=512)
     def get_block_hash(self, block_id: int) -> str:
         return self.rpc_request("chain_getBlockHash", [block_id])["result"]
 
diff --git a/async_substrate_interface/utils/cache.py b/async_substrate_interface/utils/cache.py
new file mode 100644
index 0000000..ab4f457
--- /dev/null
+++ b/async_substrate_interface/utils/cache.py
@@ -0,0 +1,134 @@
+import functools
+import os
+import pickle
+import sqlite3
+import asyncstdlib as a
+
+USE_CACHE = True if os.getenv("NO_CACHE") != "1" else False
+CACHE_LOCATION = (
+    os.path.expanduser(
+        os.getenv("CACHE_LOCATION", "~/.cache/async-substrate-interface")
+    )
+    if USE_CACHE
+    else ":memory:"
+)
+
+
+def _get_table_name(func):
+    """Convert "ClassName.method_name" to "ClassName_method_name"""
+    return func.__qualname__.replace(".", "_")
+
+
+def _check_if_local(chain: str) -> bool:
+    return any([x in chain for x in ["127.0.0.1", "localhost", "0.0.0.0"]])
+
+
+def _create_table(c, conn, table_name):
+    c.execute(
+        f"""CREATE TABLE IF NOT EXISTS {table_name} 
+        (
+           rowid INTEGER PRIMARY KEY AUTOINCREMENT,
+           key BLOB,
+           value BLOB,
+           chain TEXT,
+           created_at TIMESTAMP DEFAULT CURRENT_TIMESTAMP
+        );
+        """
+    )
+    c.execute(
+        f"""CREATE TRIGGER IF NOT EXISTS prune_rows_trigger AFTER INSERT ON {table_name}
+            BEGIN
+              DELETE FROM {table_name}
+              WHERE rowid IN (
+                SELECT rowid FROM {table_name}
+                ORDER BY created_at DESC
+                LIMIT -1 OFFSET 500
+              );
+            END;"""
+    )
+    conn.commit()
+
+
+def _retrieve_from_cache(c, table_name, key, chain):
+    try:
+        c.execute(
+            f"SELECT value FROM {table_name} WHERE key=? AND chain=?", (key, chain)
+        )
+        result = c.fetchone()
+        if result is not None:
+            return pickle.loads(result[0])
+    except (pickle.PickleError, sqlite3.Error) as e:
+        print(f"Cache error: {str(e)}")
+        pass
+
+
+def _insert_into_cache(c, conn, table_name, key, result, chain):
+    try:
+        c.execute(
+            f"INSERT OR REPLACE INTO {table_name} (key, value, chain) VALUES (?,?,?)",
+            (key, pickle.dumps(result), chain),
+        )
+        conn.commit()
+    except (pickle.PickleError, sqlite3.Error) as e:
+        print(f"Cache error: {str(e)}")
+        pass
+
+
+def sql_lru_cache(maxsize=None):
+    def decorator(func):
+        conn = sqlite3.connect(CACHE_LOCATION)
+        c = conn.cursor()
+        table_name = _get_table_name(func)
+        _create_table(c, conn, table_name)
+
+        @functools.lru_cache(maxsize=maxsize)
+        def inner(self, *args, **kwargs):
+            c = conn.cursor()
+            key = pickle.dumps((args, kwargs))
+            chain = self.url
+            if not (local_chain := _check_if_local(chain)) or not USE_CACHE:
+                result = _retrieve_from_cache(c, table_name, key, chain)
+                if result is not None:
+                    return result
+
+            # If not in DB, call func and store in DB
+            result = func(self, *args, **kwargs)
+
+            if not local_chain or not USE_CACHE:
+                _insert_into_cache(c, conn, table_name, key, result, chain)
+
+            return result
+
+        return inner
+
+    return decorator
+
+
+def async_sql_lru_cache(maxsize=None):
+    def decorator(func):
+        conn = sqlite3.connect(CACHE_LOCATION)
+        c = conn.cursor()
+        table_name = _get_table_name(func)
+        _create_table(c, conn, table_name)
+
+        @a.lru_cache(maxsize=maxsize)
+        async def inner(self, *args, **kwargs):
+            c = conn.cursor()
+            key = pickle.dumps((args, kwargs))
+            chain = self.url
+
+            if not (local_chain := _check_if_local(chain)) or not USE_CACHE:
+                result = _retrieve_from_cache(c, table_name, key, chain)
+                if result is not None:
+                    return result
+
+            # If not in DB, call func and store in DB
+            result = await func(self, *args, **kwargs)
+            if not local_chain or not USE_CACHE:
+                _insert_into_cache(c, conn, table_name, key, result, chain)
+
+            return result
+
+        return inner
+
+    return decorator