diff --git a/xla/service/gpu/transforms/copy_fusion.cc b/xla/service/gpu/transforms/copy_fusion.cc
index 1b34fb13a7290..23706a4dbcf14 100644
--- a/xla/service/gpu/transforms/copy_fusion.cc
+++ b/xla/service/gpu/transforms/copy_fusion.cc
@@ -75,7 +75,7 @@ absl::StatusOr<bool> CopyFusion::DoCopyFusion(HloComputation* computation) {
     }
     HloInstruction* root = fused_computation->root_instruction();
     if (IsReductionFromOrToContiguousDimensions(*root, device_description_) ||
-        root->opcode() == HloOpcode::kScatter ||
+        HloPredicateIsOp<HloOpcode::kScatter>(root) ||
         (hlo->IsMultiOutputFusion() &&
          absl::c_all_of(root->operands(),
                         HloPredicateIsOp<HloOpcode::kSlice>))) {
diff --git a/xla/service/gpu/transforms/double_buffer_loop_unrolling.cc b/xla/service/gpu/transforms/double_buffer_loop_unrolling.cc
index 7d217aac5674e..c46c3f53f6a84 100644
--- a/xla/service/gpu/transforms/double_buffer_loop_unrolling.cc
+++ b/xla/service/gpu/transforms/double_buffer_loop_unrolling.cc
@@ -118,9 +118,9 @@ absl::Status SetSendRecvValidationForPeeledInstr(HloInstruction* new_instr,
   TF_RET_CHECK(
       new_instr->opcode() == old_instr->opcode() &&
       "cloned instruction and original instruction have different opcodes");
-  if (!HloPredicateIsOp<HloOpcode::kCollectivePermute,
-                        HloOpcode::kCollectivePermuteStart, HloOpcode::kSend,
-                        HloOpcode::kRecv>(old_instr)) {
+  if (HloPredicateIsNotOp<HloOpcode::kCollectivePermute,
+                          HloOpcode::kCollectivePermuteStart, HloOpcode::kSend,
+                          HloOpcode::kRecv>(old_instr)) {
     return absl::OkStatus();
   }
 
@@ -188,9 +188,9 @@ absl::Status SetSendRecvValidation(HloInstruction* cp1, HloInstruction* cp2,
   TF_RET_CHECK(
       cp2->opcode() == cp1->opcode() &&
       "cloned instruction and original instruction have different opcodes");
-  if (!HloPredicateIsOp<HloOpcode::kCollectivePermute,
-                        HloOpcode::kCollectivePermuteStart, HloOpcode::kSend,
-                        HloOpcode::kRecv>(cp1)) {
+  if (HloPredicateIsNotOp<HloOpcode::kCollectivePermute,
+                          HloOpcode::kCollectivePermuteStart, HloOpcode::kSend,
+                          HloOpcode::kRecv>(cp1)) {
     return absl::OkStatus();
   }
   const auto& attribute_map = cp2->frontend_attributes().map();
diff --git a/xla/service/gpu/transforms/fusion_block_level_rewriter_test.cc b/xla/service/gpu/transforms/fusion_block_level_rewriter_test.cc
index d574fc106282a..d78dc65be9772 100644
--- a/xla/service/gpu/transforms/fusion_block_level_rewriter_test.cc
+++ b/xla/service/gpu/transforms/fusion_block_level_rewriter_test.cc
@@ -47,7 +47,7 @@ namespace {
 using ::tsl::testing::IsOkAndHolds;
 
 bool HasTritonBlockLevelFusionConfig(const HloInstruction* fusion) {
-  return fusion->opcode() == HloOpcode::kFusion &&
+  return HloPredicateIsOp<HloOpcode::kFusion>(fusion) &&
          fusion->has_backend_config() &&
          fusion->backend_config<GpuBackendConfig>().ok() &&
          fusion->backend_config<GpuBackendConfig>()
diff --git a/xla/service/gpu/transforms/rename_fusions.cc b/xla/service/gpu/transforms/rename_fusions.cc
index 29f3edf968fb3..ac396b3fd5915 100644
--- a/xla/service/gpu/transforms/rename_fusions.cc
+++ b/xla/service/gpu/transforms/rename_fusions.cc
@@ -78,7 +78,7 @@ absl::StatusOr<bool> RenameFusions::Run(
     const absl::flat_hash_set<absl::string_view>& execution_threads) {
   for (HloComputation* computation : module->MakeNonfusionComputations()) {
     for (HloInstruction* instruction : computation->instructions()) {
-      if (instruction->opcode() != HloOpcode::kFusion ||
+      if (HloPredicateIsNotOp<HloOpcode::kFusion>(instruction) ||
           instruction->fusion_kind() == HloInstruction::FusionKind::kCustom) {
         continue;
       }
diff --git a/xla/service/gpu/transforms/windowed_einsum_handler.cc b/xla/service/gpu/transforms/windowed_einsum_handler.cc
index 2ffec420c30ae..db84a666394f4 100644
--- a/xla/service/gpu/transforms/windowed_einsum_handler.cc
+++ b/xla/service/gpu/transforms/windowed_einsum_handler.cc
@@ -86,11 +86,9 @@ absl::StatusOr<bool> ShiftDequantizationF8(HloComputation* while_body) {
     HloInstruction* operand = param_tuple->mutable_operand(k);
     // Capture bitcast, broadcast, copy, reshape and transpose ops between
     // dequantization and the loop.
-    while (operand->opcode() == HloOpcode::kBitcast ||
-           operand->opcode() == HloOpcode::kBroadcast ||
-           operand->opcode() == HloOpcode::kCopy ||
-           operand->opcode() == HloOpcode::kReshape ||
-           operand->opcode() == HloOpcode::kTranspose) {
+    while (HloPredicateIsOp<HloOpcode::kBitcast, HloOpcode::kBroadcast,
+                            HloOpcode::kCopy, HloOpcode::kReshape,
+                            HloOpcode::kTranspose>(operand)) {
       unaries[k].push_back(operand);
       operand = operand->mutable_operand(0);
     }