diff --git a/crates/oxc_codegen/src/comment.rs b/crates/oxc_codegen/src/comment.rs
index 746d60edc2a05..5ef6fed220d64 100644
--- a/crates/oxc_codegen/src/comment.rs
+++ b/crates/oxc_codegen/src/comment.rs
@@ -128,7 +128,7 @@ impl Codegen<'_> {
         let comment_source = comment.span.source_text(source_text);
         match comment.kind {
             CommentKind::Line => {
-                self.print_str(comment_source);
+                self.print_str_escaping_script_close_tag(comment_source);
             }
             CommentKind::Block => {
                 // Print block comments with our own indentation.
@@ -136,7 +136,7 @@ impl Codegen<'_> {
                     if !line.starts_with("/*") {
                         self.print_indent();
                     }
-                    self.print_str(line.trim_start());
+                    self.print_str_escaping_script_close_tag(line.trim_start());
                     if !line.ends_with("*/") {
                         self.print_hard_newline();
                     }
diff --git a/crates/oxc_codegen/src/gen.rs b/crates/oxc_codegen/src/gen.rs
index 010df8b8815ca..c36137311f5c9 100644
--- a/crates/oxc_codegen/src/gen.rs
+++ b/crates/oxc_codegen/src/gen.rs
@@ -2083,7 +2083,7 @@ impl Gen for TemplateLiteral<'_> {
 
         for quasi in &self.quasis {
             p.add_source_mapping(quasi.span);
-            p.print_str(quasi.value.raw.as_str());
+            p.print_str_escaping_script_close_tag(quasi.value.raw.as_str());
             p.add_source_mapping_end(quasi.span);
 
             if let Some(expr) = expressions.next() {
diff --git a/crates/oxc_codegen/src/lib.rs b/crates/oxc_codegen/src/lib.rs
index f71bd0a420b68..78e17e978bfa0 100644
--- a/crates/oxc_codegen/src/lib.rs
+++ b/crates/oxc_codegen/src/lib.rs
@@ -26,8 +26,11 @@ use oxc_syntax::{
 };
 
 use crate::{
-    binary_expr_visitor::BinaryExpressionVisitor, comment::CommentsMap, operator::Operator,
-    sourcemap_builder::SourcemapBuilder, str::Quote,
+    binary_expr_visitor::BinaryExpressionVisitor,
+    comment::CommentsMap,
+    operator::Operator,
+    sourcemap_builder::SourcemapBuilder,
+    str::{Quote, is_script_close_tag},
 };
 pub use crate::{
     context::Context,
@@ -230,6 +233,40 @@ impl<'a> Codegen<'a> {
         self.code.print_str(s);
     }
 
+    /// Push str into the buffer, escaping `</script` to `<\/script`.
+    #[inline]
+    pub fn print_str_escaping_script_close_tag(&mut self, s: &str) {
+        let slice = s.as_bytes();
+        let mut consumed = 0;
+        let mut i = 0;
+
+        // Only check when remaining string has length larger than 8.
+        while i + 8 <= slice.len() {
+            if is_script_close_tag(&slice[i..i + 8]) {
+                // Push str up to and including `<`. Skip `/`. Write `\/` instead.
+                // SAFETY:
+                // The slice guarantees to be a valid UTF-8 string.
+                // The consumed index is always pointed to a UTF-8 char boundary.
+                // Current byte is `<`, a UTF-8 char boundary.
+                unsafe {
+                    self.code.print_bytes_unchecked(&slice[consumed..=i]);
+                }
+                self.code.print_str("\\/");
+                consumed = i + 2;
+                i += 8;
+            } else {
+                i += 1;
+            }
+        }
+
+        // SAFETY:
+        // The slice guarantees to be a valid UTF-8 string.
+        // The consumed index is always pointed to a UTF-8 char boundary.
+        unsafe {
+            self.code.print_bytes_unchecked(&slice[consumed..]);
+        }
+    }
+
     /// Print a single [`Expression`], adding it to the code generator's
     /// internal buffer. Unlike [`Codegen::build`], this does not consume `self`.
     #[inline]
diff --git a/crates/oxc_codegen/src/str.rs b/crates/oxc_codegen/src/str.rs
index 76c32b0fffcf6..cbb2da8b14f00 100644
--- a/crates/oxc_codegen/src/str.rs
+++ b/crates/oxc_codegen/src/str.rs
@@ -340,9 +340,10 @@ enum Escape {
     DQ = 11, // "     - Double quote
     BQ = 12, // `     - Backtick quote
     DO = 13, // $     - Dollar sign
-    LS = 14, // LS/PS - U+2028 LINE SEPARATOR or U+2029 PARAGRAPH SEPARATOR (first byte)
-    NB = 15, // NBSP  - Non-breaking space (first byte)
-    LO = 16, // �     - U+FFFD lossy replacement character (first byte)
+    LT = 14, // <     - Less-than sign
+    LS = 15, // LS/PS - U+2028 LINE SEPARATOR or U+2029 PARAGRAPH SEPARATOR (first byte)
+    NB = 16, // NBSP  - Non-breaking space (first byte)
+    LO = 17, // �     - U+FFFD lossy replacement character (first byte)
 }
 
 /// Struct which ensures content is aligned on 128.
@@ -362,7 +363,7 @@ static ESCAPES: Aligned128<[Escape; 256]> = {
         NU, __, __, __, __, __, __, BE, BK, __, NL, VT, FF, CR, __, __, // 0
         __, __, __, __, __, __, __, __, __, __, __, ES, __, __, __, __, // 1
         __, __, DQ, __, DO, __, __, SQ, __, __, __, __, __, __, __, __, // 2
-        __, __, __, __, __, __, __, __, __, __, __, __, __, __, __, __, // 3
+        __, __, __, __, __, __, __, __, __, __, __, __, LT, __, __, __, // 3
         __, __, __, __, __, __, __, __, __, __, __, __, __, __, __, __, // 4
         __, __, __, __, __, __, __, __, __, __, __, __, BS, __, __, __, // 5
         BQ, __, __, __, __, __, __, __, __, __, __, __, __, __, __, __, // 6
@@ -385,9 +386,10 @@ type ByteHandler = unsafe fn(&mut Codegen, &mut PrintStringState);
 /// Indexed by `escape as usize - 1` (where `escape` is not `Escape::__`).
 /// Must be in same order as discriminants in `Escape`.
 ///
-/// Function pointers are 8 bytes each, so `BYTE_HANDLERS` is 128 bytes in total.
-/// Aligned on 128, so occupies a pair of L1 cache lines.
-static BYTE_HANDLERS: Aligned128<[ByteHandler; 16]> = Aligned128([
+/// Function pointers are 8 bytes each, so `BYTE_HANDLERS` is 136 bytes in total.
+/// Aligned on 128, so first 16 occupy a pair of L1 cache lines.
+/// The last will be in separate cache line, but it should be vanishingly rare that it's accessed.
+static BYTE_HANDLERS: Aligned128<[ByteHandler; 17]> = Aligned128([
     print_null,
     print_bell,
     print_backspace,
@@ -401,6 +403,7 @@ static BYTE_HANDLERS: Aligned128<[ByteHandler; 16]> = Aligned128([
     print_double_quote,
     print_backtick,
     print_dollar,
+    print_less_than,
     print_ls_or_ps,
     print_non_breaking_space,
     print_lossy_replacement,
@@ -579,6 +582,29 @@ unsafe fn print_dollar(codegen: &mut Codegen, state: &mut PrintStringState) {
     }
 }
 
+// <
+unsafe fn print_less_than(codegen: &mut Codegen, state: &mut PrintStringState) {
+    debug_assert_eq!(state.peek(), Some(b'<'));
+
+    // Get slice of remaining bytes, including leading `<`
+    let slice = state.bytes.as_slice();
+
+    // SAFETY: Next byte is `<`, which is ASCII
+    unsafe { state.consume_byte_unchecked() };
+
+    if slice.len() >= 8 && is_script_close_tag(&slice[0..8]) {
+        // Flush up to and including `<`. Skip `/`. Write `\/` instead. Then skip over `script`.
+        // Next chunk starts with `script`.
+        // SAFETY: We already consumed `<`. Next byte is `/`, which is ASCII.
+        unsafe { state.flush_and_consume_byte(codegen) };
+        codegen.print_str("\\/");
+        // SAFETY: The check above ensures there are 6 bytes left, after consuming 2 already.
+        // `script` / `SCRIPT` is all ASCII bytes, so skipping them leaves `bytes` iterator
+        // positioned on UTF-8 char boundary.
+        unsafe { state.consume_bytes_unchecked::<6>() };
+    }
+}
+
 // 0xE2 - first byte of <LS> or <PS>
 unsafe fn print_ls_or_ps(codegen: &mut Codegen, state: &mut PrintStringState) {
     debug_assert_eq!(state.peek(), Some(0xE2));
@@ -696,3 +722,20 @@ unsafe fn print_lossy_replacement(codegen: &mut Codegen, state: &mut PrintString
 pub fn cold_branch<F: FnOnce() -> T, T>(f: F) -> T {
     f()
 }
+
+/// Check if the slice is `</script` regardless of case.
+pub fn is_script_close_tag(slice: &[u8]) -> bool {
+    if slice.len() == 8 {
+        // Compiler condenses these operations to an 8-byte read, u64 AND, and u64 compare.
+        // https://godbolt.org/z/oGG16fK6v
+        let mut slice: [u8; 8] = slice.try_into().unwrap();
+        for b in slice.iter_mut().skip(2) {
+            // `| 32` converts ASCII upper case letters to lower case.
+            *b |= 32;
+        }
+
+        slice == *b"</script"
+    } else {
+        false
+    }
+}
diff --git a/crates/oxc_codegen/tests/integration/esbuild.rs b/crates/oxc_codegen/tests/integration/esbuild.rs
index f35605ad1b091..5b4bdcb7ad4fc 100644
--- a/crates/oxc_codegen/tests/integration/esbuild.rs
+++ b/crates/oxc_codegen/tests/integration/esbuild.rs
@@ -1014,15 +1014,21 @@ fn test_jsx_single_line() {
 }
 
 #[test]
-#[ignore]
 fn test_avoid_slash_script() {
     // Positive cases
     test("x = '</script'", "x = \"<\\/script\";\n");
+    test("x = '</SCRIPT'", "x = \"<\\/SCRIPT\";\n");
+    test("x = '</ScRiPt'", "x = \"<\\/ScRiPt\";\n");
+    test("x = 'abc </script def'", "x = \"abc <\\/script def\";\n");
+    test("x = 'abc </ScRiPt def'", "x = \"abc <\\/ScRiPt def\";\n");
     test("x = `</script`", "x = `<\\/script`;\n");
     test("x = `</SCRIPT`", "x = `<\\/SCRIPT`;\n");
     test("x = `</ScRiPt`", "x = `<\\/ScRiPt`;\n");
     test("x = `</script${y}`", "x = `<\\/script${y}`;\n");
     test("x = `${y}</script`", "x = `${y}<\\/script`;\n");
+    test("x = `<</script`", "x = `<<\\/script`;\n");
+    test("x = `</</script`", "x = `</<\\/script`;\n");
+    test("x = `</script</script`", "x = `<\\/script<\\/script`;\n");
     test_minify("x = 1 < /script/.exec(y).length", "x=1< /script/.exec(y).length;");
     test_minify("x = 1 < /SCRIPT/.exec(y).length", "x=1< /SCRIPT/.exec(y).length;");
     test_minify("x = 1 < /ScRiPt/.exec(y).length", "x=1< /ScRiPt/.exec(y).length;");
@@ -1030,29 +1036,14 @@ fn test_avoid_slash_script() {
     test("//! </script\n//! >/script\n//! /script", "//! <\\/script\n//! >/script\n//! /script\n");
     test("//! </SCRIPT\n//! >/SCRIPT\n//! /SCRIPT", "//! <\\/SCRIPT\n//! >/SCRIPT\n//! /SCRIPT\n");
     test("//! </ScRiPt\n//! >/ScRiPt\n//! /ScRiPt", "//! <\\/ScRiPt\n//! >/ScRiPt\n//! /ScRiPt\n");
-    test("/*! </script \n </script */", "/*! <\\/script \n <\\/script */\n");
-    test("/*! </SCRIPT \n </SCRIPT */", "/*! <\\/SCRIPT \n <\\/SCRIPT */\n");
-    test("/*! </ScRiPt \n </ScRiPt */", "/*! <\\/ScRiPt \n <\\/ScRiPt */\n");
-    test(
-        "String.raw`</script`",
-        "import { __template } from \"<runtime>\";\nvar _a;\nString.raw(_a || (_a = __template([\"<\\/script\"])));\n",
-    );
-    test(
-        "String.raw`</script${a}`",
-        "import { __template } from \"<runtime>\";\nvar _a;\nString.raw(_a || (_a = __template([\"<\\/script\", \"\"])), a);\n",
-    );
-    test(
-        "String.raw`${a}</script`",
-        "import { __template } from \"<runtime>\";\nvar _a;\nString.raw(_a || (_a = __template([\"\", \"<\\/script\"])), a);\n",
-    );
-    test(
-        "String.raw`</SCRIPT`",
-        "import { __template } from \"<runtime>\";\nvar _a;\nString.raw(_a || (_a = __template([\"<\\/SCRIPT\"])));\n",
-    );
-    test(
-        "String.raw`</ScRiPt`",
-        "import { __template } from \"<runtime>\";\nvar _a;\nString.raw(_a || (_a = __template([\"<\\/ScRiPt\"])));\n",
-    );
+    test("/*! </script \n</script */", "/*! <\\/script \n<\\/script */");
+    test("/*! </SCRIPT \n</SCRIPT */", "/*! <\\/SCRIPT \n<\\/SCRIPT */");
+    test("/*! </ScRiPt \n</ScRiPt */", "/*! <\\/ScRiPt \n<\\/ScRiPt */");
+    test("String.raw`</script`", "String.raw`<\\/script`;\n");
+    test("String.raw`</script${a}`", "String.raw`<\\/script${a}`;\n");
+    test("String.raw`${a}</script`", "String.raw`${a}<\\/script`;\n");
+    test("String.raw`</SCRIPT`", "String.raw`<\\/SCRIPT`;\n");
+    test("String.raw`</ScRiPt`", "String.raw`<\\/ScRiPt`;\n");
 
     // Negative cases
     test("x = '</'", "x = \"</\";\n");