diff --git a/pandas/conftest.py b/pandas/conftest.py
index 97cc514e31bb3..0878380d00837 100644
--- a/pandas/conftest.py
+++ b/pandas/conftest.py
@@ -1181,7 +1181,13 @@ def ip():
     pytest.importorskip("IPython", minversion="6.0.0")
     from IPython.core.interactiveshell import InteractiveShell
 
-    return InteractiveShell()
+    # GH#35711 make sure sqlite history file handle is not leaked
+    from traitlets.config import Config  # noqa: F401 isort:skip
+
+    c = Config()
+    c.HistoryManager.hist_file = ":memory:"
+
+    return InteractiveShell(config=c)
 
 
 @pytest.fixture(params=["bsr", "coo", "csc", "csr", "dia", "dok", "lil"])
diff --git a/pandas/tests/frame/test_api.py b/pandas/tests/frame/test_api.py
index 2fb1f7f911a9c..0716cf5e27119 100644
--- a/pandas/tests/frame/test_api.py
+++ b/pandas/tests/frame/test_api.py
@@ -6,6 +6,7 @@
 import numpy as np
 import pytest
 
+import pandas.util._test_decorators as td
 from pandas.util._test_decorators import async_mark, skip_if_no
 
 import pandas as pd
@@ -521,6 +522,7 @@ def _check_f(base, f):
         _check_f(d.copy(), f)
 
     @async_mark()
+    @td.check_file_leaks
     async def test_tab_complete_warning(self, ip):
         # GH 16409
         pytest.importorskip("IPython", minversion="6.0.0")
diff --git a/pandas/tests/io/formats/test_format.py b/pandas/tests/io/formats/test_format.py
index 84805d06df4a8..1bbfe4d7d74af 100644
--- a/pandas/tests/io/formats/test_format.py
+++ b/pandas/tests/io/formats/test_format.py
@@ -19,6 +19,7 @@
 import pytz
 
 from pandas.compat import is_platform_32bit, is_platform_windows
+import pandas.util._test_decorators as td
 
 import pandas as pd
 from pandas import (
@@ -3338,6 +3339,7 @@ def test_format_percentiles_integer_idx():
     assert result == expected
 
 
+@td.check_file_leaks
 def test_repr_html_ipython_config(ip):
     code = textwrap.dedent(
         """\
diff --git a/pandas/tests/resample/test_resampler_grouper.py b/pandas/tests/resample/test_resampler_grouper.py
index b36b11582c1ec..f18aaa5e86829 100644
--- a/pandas/tests/resample/test_resampler_grouper.py
+++ b/pandas/tests/resample/test_resampler_grouper.py
@@ -3,6 +3,7 @@
 import numpy as np
 import pytest
 
+import pandas.util._test_decorators as td
 from pandas.util._test_decorators import async_mark
 
 import pandas as pd
@@ -17,6 +18,7 @@
 
 
 @async_mark()
+@td.check_file_leaks
 async def test_tab_complete_ipython6_warning(ip):
     from IPython.core.completer import provisionalcompleter
 
diff --git a/pandas/tests/series/test_api.py b/pandas/tests/series/test_api.py
index b174eb0e42776..d81e8a4f82ffb 100644
--- a/pandas/tests/series/test_api.py
+++ b/pandas/tests/series/test_api.py
@@ -5,6 +5,7 @@
 import numpy as np
 import pytest
 
+import pandas.util._test_decorators as td
 from pandas.util._test_decorators import async_mark
 
 import pandas as pd
@@ -486,6 +487,7 @@ def test_empty_method(self):
             assert not full_series.empty
 
     @async_mark()
+    @td.check_file_leaks
     async def test_tab_complete_warning(self, ip):
         # https://github.com/pandas-dev/pandas/issues/16409
         pytest.importorskip("IPython", minversion="6.0.0")