diff --git a/pandas/tests/arrays/string_/test_string.py b/pandas/tests/arrays/string_/test_string.py
index 6a17a56a47cbc..5b4d586e69c1b 100644
--- a/pandas/tests/arrays/string_/test_string.py
+++ b/pandas/tests/arrays/string_/test_string.py
@@ -611,3 +611,11 @@ def test_setitem_scalar_with_mask_validation(dtype):
         msg = "Scalar must be NA or str"
     with pytest.raises(ValueError, match=msg):
         ser[mask] = 1
+
+
+def test_consitency_inplace():
+    expected = pd.DataFrame({"M": [""]}, dtype="string")
+    df = pd.DataFrame({"M": [""]}, dtype="string")
+    df.where(df != "", np.nan, inplace=True)
+    expected = expected.where(expected != "", np.nan)
+    tm.assert_frame_equal(expected, df)