diff --git a/src/python/pants/backend/python/goals/tailor.py b/src/python/pants/backend/python/goals/tailor.py
index 631be695203..9fa5ebe0633 100644
--- a/src/python/pants/backend/python/goals/tailor.py
+++ b/src/python/pants/backend/python/goals/tailor.py
@@ -121,22 +121,41 @@ async def find_putative_targets(
 
     if python_setup.tailor_requirements_targets:
         # Find requirements files.
-        all_requirements_files = await Get(
-            Paths, PathGlobs, req.search_paths.path_globs("*requirements*.txt")
+        (
+            all_requirements_files,
+            all_pipenv_lockfile_files,
+            all_pyproject_toml_contents,
+        ) = await MultiGet(
+            Get(Paths, PathGlobs, req.search_paths.path_globs("*requirements*.txt")),
+            Get(Paths, PathGlobs, req.search_paths.path_globs("Pipfile.lock")),
+            Get(DigestContents, PathGlobs, req.search_paths.path_globs("pyproject.toml")),
         )
-        unowned_requirements_files = set(all_requirements_files.files) - set(all_owned_sources)
-        for req_file in unowned_requirements_files:
-            path, name = os.path.split(req_file)
-            pts.append(
-                PutativeTarget(
-                    path=path,
-                    name=name,
-                    type_alias="python_requirements",
-                    triggering_sources=[req_file],
-                    owned_sources=[name],
-                    kwargs={} if name == "requirements.txt" else {"source": name},
+
+        def add_req_targets(files: Iterable[str], alias: str) -> None:
+            unowned_files = set(files) - set(all_owned_sources)
+            for fp in unowned_files:
+                path, name = os.path.split(fp)
+                pts.append(
+                    PutativeTarget(
+                        path=path,
+                        name=name,
+                        type_alias=alias,
+                        triggering_sources=[fp],
+                        owned_sources=[name],
+                        kwargs=(
+                            {}
+                            if alias != "python_requirements" or name == "requirements.txt"
+                            else {"source": name}
+                        ),
+                    )
                 )
-            )
+
+        add_req_targets(all_requirements_files.files, "python_requirements")
+        add_req_targets(all_pipenv_lockfile_files.files, "pipenv_requirements")
+        add_req_targets(
+            {fc.path for fc in all_pyproject_toml_contents if b"[tool.poetry" in fc.content},
+            "poetry_requirements",
+        )
 
     if python_setup.tailor_pex_binary_targets:
         # Find binary targets.
diff --git a/src/python/pants/backend/python/goals/tailor_test.py b/src/python/pants/backend/python/goals/tailor_test.py
index 2e7d5470d74..9a8204f4aab 100644
--- a/src/python/pants/backend/python/goals/tailor_test.py
+++ b/src/python/pants/backend/python/goals/tailor_test.py
@@ -11,6 +11,8 @@
     classify_source_files,
     is_entry_point,
 )
+from pants.backend.python.macros.pipenv_requirements import PipenvRequirementsTargetGenerator
+from pants.backend.python.macros.poetry_requirements import PoetryRequirementsTargetGenerator
 from pants.backend.python.macros.python_requirements import PythonRequirementsTargetGenerator
 from pants.backend.python.target_types import (
     PexBinary,
@@ -68,8 +70,13 @@ def test_find_putative_targets(rule_runner: RuleRunner) -> None:
     rule_runner.set_options(["--no-python-tailor-ignore-solitary-init-files"])
     rule_runner.write_files(
         {
+            "3rdparty/Pipfile.lock": "",
+            "3rdparty/pyproject.toml": "[tool.poetry]",
             "3rdparty/requirements-test.txt": "",
             "already_owned/requirements.txt": "",
+            "already_owned/Pipfile.lock": "",
+            "already_owned/pyproject.toml": "[tool.poetry]",
+            "no_match/pyproject.toml": "# no poetry section",
             **{
                 f"src/python/foo/{fp}": ""
                 for fp in (
@@ -92,6 +99,8 @@ def test_find_putative_targets(rule_runner: RuleRunner) -> None:
             AllOwnedSources(
                 [
                     "already_owned/requirements.txt",
+                    "already_owned/Pipfile.lock",
+                    "already_owned/pyproject.toml",
                     "src/python/foo/bar/__init__.py",
                     "src/python/foo/bar/baz1.py",
                 ]
@@ -101,6 +110,18 @@ def test_find_putative_targets(rule_runner: RuleRunner) -> None:
     assert (
         PutativeTargets(
             [
+                PutativeTarget.for_target_type(
+                    PipenvRequirementsTargetGenerator,
+                    path="3rdparty",
+                    name="Pipfile.lock",
+                    triggering_sources=["3rdparty/Pipfile.lock"],
+                ),
+                PutativeTarget.for_target_type(
+                    PoetryRequirementsTargetGenerator,
+                    path="3rdparty",
+                    name="pyproject.toml",
+                    triggering_sources=["3rdparty/pyproject.toml"],
+                ),
                 PutativeTarget.for_target_type(
                     PythonRequirementsTargetGenerator,
                     path="3rdparty",
diff --git a/src/python/pants/backend/python/subsystems/setup.py b/src/python/pants/backend/python/subsystems/setup.py
index 43e3ddf9033..a83831d01c0 100644
--- a/src/python/pants/backend/python/subsystems/setup.py
+++ b/src/python/pants/backend/python/subsystems/setup.py
@@ -432,11 +432,15 @@ class PythonSetup(Subsystem):
         default=True,
         help=softwrap(
             """
-            If true, add `python_requirements` target generators with the `tailor` goal for
-            requirements files.
+            If true, add `python_requirements`, `poetry_requirements`, and `pipenv_requirements`
+            target generators with the `tailor` goal.
 
-            This matches any file with the pattern `*requirements*.txt`. You will need to manually
-            add `python_requirements` for different file names like `reqs.txt`.
+            `python_requirements` targets are added for any file that matches the pattern
+            `*requirements*.txt`. You will need to manually add `python_requirements` for different
+            file names like `reqs.txt`.
+
+            `poetry_requirements` targets are added for `pyproject.toml` files with `[tool.poetry`
+            in them.
             """
         ),
         advanced=True,