diff --git a/relays/bin-substrate/src/cli/init_bridge.rs b/relays/bin-substrate/src/cli/init_bridge.rs
index 7b38d812271..f297a8db6b4 100644
--- a/relays/bin-substrate/src/cli/init_bridge.rs
+++ b/relays/bin-substrate/src/cli/init_bridge.rs
@@ -19,6 +19,10 @@ use codec::Encode;
 
 use crate::{
 	bridges::{
+		kusama_polkadot::{
+			kusama_headers_to_bridge_hub_polkadot::KusamaToBridgeHubPolkadotCliBridge,
+			polkadot_headers_to_bridge_hub_kusama::PolkadotToBridgeHubKusamaCliBridge,
+		},
 		rialto_millau::{
 			millau_headers_to_rialto::MillauToRialtoCliBridge,
 			rialto_headers_to_millau::RialtoToMillauCliBridge,
@@ -66,6 +70,8 @@ pub enum InitBridgeName {
 	MillauToRialtoParachain,
 	RococoToBridgeHubWococo,
 	WococoToBridgeHubRococo,
+	KusamaToBridgeHubPolkadot,
+	PolkadotToBridgeHubKusama,
 }
 
 #[async_trait]
@@ -198,6 +204,34 @@ impl BridgeInitializer for WococoToBridgeHubRococoCliBridge {
 	}
 }
 
+impl BridgeInitializer for KusamaToBridgeHubPolkadotCliBridge {
+	type Engine = GrandpaFinalityEngine<Self::Source>;
+
+	fn encode_init_bridge(
+		init_data: <Self::Engine as Engine<Self::Source>>::InitializationData,
+	) -> <Self::Target as Chain>::Call {
+		relay_bridge_hub_polkadot_client::runtime::Call::BridgeKusamaGrandpa(
+			relay_bridge_hub_polkadot_client::runtime::BridgeKusamaGrandpaCall::initialize {
+				init_data,
+			},
+		)
+	}
+}
+
+impl BridgeInitializer for PolkadotToBridgeHubKusamaCliBridge {
+	type Engine = GrandpaFinalityEngine<Self::Source>;
+
+	fn encode_init_bridge(
+		init_data: <Self::Engine as Engine<Self::Source>>::InitializationData,
+	) -> <Self::Target as Chain>::Call {
+		relay_bridge_hub_kusama_client::runtime::Call::BridgePolkadotGrandpa(
+			relay_bridge_hub_kusama_client::runtime::BridgePolkadotGrandpaCall::initialize {
+				init_data,
+			},
+		)
+	}
+}
+
 impl InitBridge {
 	/// Run the command.
 	pub async fn run(self) -> anyhow::Result<()> {
@@ -211,6 +245,10 @@ impl InitBridge {
 				RococoToBridgeHubWococoCliBridge::init_bridge(self),
 			InitBridgeName::WococoToBridgeHubRococo =>
 				WococoToBridgeHubRococoCliBridge::init_bridge(self),
+			InitBridgeName::KusamaToBridgeHubPolkadot =>
+				KusamaToBridgeHubPolkadotCliBridge::init_bridge(self),
+			InitBridgeName::PolkadotToBridgeHubKusama =>
+				PolkadotToBridgeHubKusamaCliBridge::init_bridge(self),
 		}
 		.await
 	}
diff --git a/relays/bin-substrate/src/cli/relay_headers_and_messages/mod.rs b/relays/bin-substrate/src/cli/relay_headers_and_messages/mod.rs
index 5384c8ff9e9..a47283400aa 100644
--- a/relays/bin-substrate/src/cli/relay_headers_and_messages/mod.rs
+++ b/relays/bin-substrate/src/cli/relay_headers_and_messages/mod.rs
@@ -40,6 +40,10 @@ use relay_to_relay::*;
 
 use crate::{
 	bridges::{
+		kusama_polkadot::{
+			kusama_parachains_to_bridge_hub_polkadot::BridgeHubKusamaToBridgeHubPolkadotCliBridge,
+			polkadot_parachains_to_bridge_hub_kusama::BridgeHubPolkadotToBridgeHubKusamaCliBridge,
+		},
 		rialto_millau::{
 			millau_headers_to_rialto::MillauToRialtoCliBridge,
 			rialto_headers_to_millau::RialtoToMillauCliBridge,
@@ -202,6 +206,10 @@ declare_chain_cli_schema!(Rococo, rococo);
 declare_chain_cli_schema!(BridgeHubRococo, bridge_hub_rococo);
 declare_chain_cli_schema!(Wococo, wococo);
 declare_chain_cli_schema!(BridgeHubWococo, bridge_hub_wococo);
+declare_chain_cli_schema!(Kusama, kusama);
+declare_chain_cli_schema!(BridgeHubKusama, bridge_hub_kusama);
+declare_chain_cli_schema!(Polkadot, polkadot);
+declare_chain_cli_schema!(BridgeHubPolkadot, bridge_hub_polkadot);
 // Means to override signers of different layer transactions.
 declare_chain_cli_schema!(MillauHeadersToRialto, millau_headers_to_rialto);
 declare_chain_cli_schema!(MillauHeadersToRialtoParachain, millau_headers_to_rialto_parachain);
@@ -217,10 +225,21 @@ declare_chain_cli_schema!(
 	WococoParachainsToBridgeHubRococo,
 	wococo_parachains_to_bridge_hub_rococo
 );
+declare_chain_cli_schema!(KusamaHeadersToBridgeHubPolkadot, kusama_headers_to_bridge_hub_polkadot);
+declare_chain_cli_schema!(
+	KusamaParachainsToBridgeHubPolkadot,
+	kusama_parachains_to_bridge_hub_polkadot
+);
+declare_chain_cli_schema!(PolkadotHeadersToBridgeHubKusama, polkadot_headers_to_bridge_hub_kusama);
+declare_chain_cli_schema!(
+	PolkadotParachainsToBridgeHubKusama,
+	polkadot_parachains_to_bridge_hub_kusama
+);
 // All supported bridges.
 declare_relay_to_relay_bridge_schema!(Millau, Rialto);
 declare_relay_to_parachain_bridge_schema!(Millau, RialtoParachain, Rialto);
 declare_parachain_to_parachain_bridge_schema!(BridgeHubRococo, Rococo, BridgeHubWococo, Wococo);
+declare_parachain_to_parachain_bridge_schema!(BridgeHubKusama, Kusama, BridgeHubPolkadot, Polkadot);
 
 /// Base portion of the bidirectional complex relay.
 ///
@@ -463,6 +482,32 @@ impl Full2WayBridge for BridgeHubRococoBridgeHubWococoFull2WayBridge {
 	}
 }
 
+/// BridgeHubKusama <> BridgeHubPolkadot complex relay.
+pub struct BridgeHubKusamaBridgeHubPolkadotFull2WayBridge {
+	base: <Self as Full2WayBridge>::Base,
+}
+
+#[async_trait]
+impl Full2WayBridge for BridgeHubKusamaBridgeHubPolkadotFull2WayBridge {
+	type Base = ParachainToParachainBridge<Self::L2R, Self::R2L>;
+	type Left = relay_bridge_hub_kusama_client::BridgeHubKusama;
+	type Right = relay_bridge_hub_polkadot_client::BridgeHubPolkadot;
+	type L2R = BridgeHubKusamaToBridgeHubPolkadotCliBridge;
+	type R2L = BridgeHubPolkadotToBridgeHubKusamaCliBridge;
+
+	fn new(base: Self::Base) -> anyhow::Result<Self> {
+		Ok(Self { base })
+	}
+
+	fn base(&self) -> &Self::Base {
+		&self.base
+	}
+
+	fn mut_base(&mut self) -> &mut Self::Base {
+		&mut self.base
+	}
+}
+
 /// Complex headers+messages relay.
 #[derive(Debug, PartialEq, StructOpt)]
 pub enum RelayHeadersAndMessages {
@@ -472,6 +517,8 @@ pub enum RelayHeadersAndMessages {
 	MillauRialtoParachain(MillauRialtoParachainHeadersAndMessages),
 	/// BridgeHubRococo <> BridgeHubWococo relay.
 	BridgeHubRococoBridgeHubWococo(BridgeHubRococoBridgeHubWococoHeadersAndMessages),
+	/// BridgeHubKusama <> BridgeHubPolkadot relay.
+	BridgeHubKusamaBridgeHubPolkadot(BridgeHubKusamaBridgeHubPolkadotHeadersAndMessages),
 }
 
 impl RelayHeadersAndMessages {
@@ -488,6 +535,10 @@ impl RelayHeadersAndMessages {
 				BridgeHubRococoBridgeHubWococoFull2WayBridge::new(params.into_bridge().await?)?
 					.run()
 					.await,
+			RelayHeadersAndMessages::BridgeHubKusamaBridgeHubPolkadot(params) =>
+				BridgeHubKusamaBridgeHubPolkadotFull2WayBridge::new(params.into_bridge().await?)?
+					.run()
+					.await,
 		}
 	}
 }