diff --git a/phpstan-baseline.neon b/phpstan-baseline.neon
index a98bb95..c544185 100644
--- a/phpstan-baseline.neon
+++ b/phpstan-baseline.neon
@@ -14,3 +14,8 @@ parameters:
 			message: "#^Function frankenphp_handle_request not found\\.$#"
 			count: 1
 			path: src/frankenphp-symfony/src/Runner.php
+
+		-
+			message: "#^Function frankenphp_handle_request not found\\.$#"
+			count: 1
+			path: src/frankenphp-symfony/src/ResponseRunner.php
diff --git a/psalm.baseline.xml b/psalm.baseline.xml
index cc89e29..8b41bd5 100644
--- a/psalm.baseline.xml
+++ b/psalm.baseline.xml
@@ -20,6 +20,11 @@
       <code><![CDATA[$options]]></code>
     </InvalidArgument>
   </file>
+  <file src="src/frankenphp-symfony/src/ResponseRunner.php">
+    <UndefinedFunction>
+      <code><![CDATA[\frankenphp_handle_request($handler)]]></code>
+    </UndefinedFunction>
+  </file>
   <file src="src/google-cloud/router.php">
     <MissingFile>
       <code><![CDATA[require_once $_SERVER['SCRIPT_FILENAME'] = $defaultSource]]></code>
diff --git a/src/frankenphp-symfony/src/ResponseRunner.php b/src/frankenphp-symfony/src/ResponseRunner.php
new file mode 100644
index 0000000..ecdc373
--- /dev/null
+++ b/src/frankenphp-symfony/src/ResponseRunner.php
@@ -0,0 +1,55 @@
+<?php
+
+declare(strict_types=1);
+
+namespace Runtime\FrankenPhpSymfony;
+
+use Symfony\Component\HttpFoundation\Request;
+use Symfony\Component\HttpFoundation\Response;
+use Symfony\Component\Runtime\RunnerInterface;
+
+/**
+ * A response runner for FrankenPHP.
+ *
+ * @author Kévin Dunglas <kevin@dunglas.dev>
+ */
+class ResponseRunner implements RunnerInterface
+{
+    public function __construct(
+        private Response $response,
+        private int $loopMax,
+    ) {
+    }
+
+    public function run(): int
+    {
+        // Prevent worker script termination when a client connection is interrupted
+        ignore_user_abort(true);
+
+        $xdebugConnectToClient = function_exists('xdebug_connect_to_client');
+
+        $server = array_filter($_SERVER, static fn (string $key) => !str_starts_with($key, 'HTTP_'), ARRAY_FILTER_USE_KEY);
+        $server['APP_RUNTIME_MODE'] = 'web=1&worker=1';
+
+        $handler = function () use ($server, $xdebugConnectToClient): void {
+            // Connect to the Xdebug client if it's available
+            if ($xdebugConnectToClient) {
+                xdebug_connect_to_client();
+            }
+
+            // Merge the environment variables coming from DotEnv with the ones tied to the current request
+            $_SERVER += $server;
+
+            $this->response->send();
+        };
+
+        $loops = 0;
+        do {
+            $ret = \frankenphp_handle_request($handler);
+
+            gc_collect_cycles();
+        } while ($ret && (-1 === $this->loopMax || ++$loops < $this->loopMax));
+
+        return 0;
+    }
+}
diff --git a/src/frankenphp-symfony/src/Runtime.php b/src/frankenphp-symfony/src/Runtime.php
index efae98b..1a8bf25 100644
--- a/src/frankenphp-symfony/src/Runtime.php
+++ b/src/frankenphp-symfony/src/Runtime.php
@@ -4,6 +4,7 @@
 
 namespace Runtime\FrankenPhpSymfony;
 
+use Symfony\Component\HttpFoundation\Response;
 use Symfony\Component\HttpKernel\HttpKernelInterface;
 use Symfony\Component\Runtime\RunnerInterface;
 use Symfony\Component\Runtime\SymfonyRuntime;
@@ -29,8 +30,14 @@ public function __construct(array $options = [])
 
     public function getRunner(?object $application): RunnerInterface
     {
-        if ($application instanceof HttpKernelInterface && ($_SERVER['FRANKENPHP_WORKER'] ?? false)) {
-            return new Runner($application, $this->options['frankenphp_loop_max']);
+        if ($_SERVER['FRANKENPHP_WORKER'] ?? false) {
+            if ($application instanceof HttpKernelInterface) {
+                return new Runner($application, $this->options['frankenphp_loop_max']);
+            }
+
+            if ($application instanceof Response) {
+                return new ResponseRunner($application, $this->options['frankenphp_loop_max']);
+            }
         }
 
         return parent::getRunner($application);
diff --git a/src/frankenphp-symfony/tests/RunnerTest.php b/src/frankenphp-symfony/tests/RunnerTest.php
index 8d3caa7..9440f1b 100644
--- a/src/frankenphp-symfony/tests/RunnerTest.php
+++ b/src/frankenphp-symfony/tests/RunnerTest.php
@@ -7,6 +7,7 @@
 require_once __DIR__.'/function-mock.php';
 
 use PHPUnit\Framework\TestCase;
+use Runtime\FrankenPhpSymfony\ResponseRunner;
 use Runtime\FrankenPhpSymfony\Runner;
 use Symfony\Component\HttpFoundation\Request;
 use Symfony\Component\HttpFoundation\Response;
@@ -22,6 +23,17 @@ interface TestAppInterface extends HttpKernelInterface, TerminableInterface
  */
 class RunnerTest extends TestCase
 {
+    public function testResponseRun(): void
+    {
+        $application = $this->createMock(Response::class);
+        $application
+            ->expects($this->once())
+            ->method('send');
+
+        $runner = new ResponseRunner($application, 500);
+        $this->assertSame(0, $runner->run());
+    }
+
     public function testRun(): void
     {
         $application = $this->createMock(TestAppInterface::class);
diff --git a/src/frankenphp-symfony/tests/RuntimeTest.php b/src/frankenphp-symfony/tests/RuntimeTest.php
index cc91527..c11e419 100644
--- a/src/frankenphp-symfony/tests/RuntimeTest.php
+++ b/src/frankenphp-symfony/tests/RuntimeTest.php
@@ -5,8 +5,10 @@
 namespace Runtime\FrankenPhpSymfony\Tests;
 
 use PHPUnit\Framework\TestCase;
+use Runtime\FrankenPhpSymfony\ResponseRunner;
 use Runtime\FrankenPhpSymfony\Runner;
 use Runtime\FrankenPhpSymfony\Runtime;
+use Symfony\Component\HttpFoundation\Response;
 use Symfony\Component\HttpKernel\HttpKernelInterface;
 
 /**
@@ -16,6 +18,7 @@ final class RuntimeTest extends TestCase
 {
     public function testGetRunner(): void
     {
+        unset($_SERVER['FRANKENPHP_WORKER']);
         $application = $this->createStub(HttpKernelInterface::class);
 
         $runtime = new Runtime();
@@ -25,4 +28,17 @@ public function testGetRunner(): void
         $_SERVER['FRANKENPHP_WORKER'] = 1;
         $this->assertInstanceOf(Runner::class, $runtime->getRunner($application));
     }
+
+    public function testGetResponseRunner(): void
+    {
+        unset($_SERVER['FRANKENPHP_WORKER']);
+        $application = $this->createStub(Response::class);
+
+        $runtime = new Runtime();
+        $this->assertNotInstanceOf(ResponseRunner::class, $runtime->getRunner(null));
+        $this->assertNotInstanceOf(ResponseRunner::class, $runtime->getRunner($application));
+
+        $_SERVER['FRANKENPHP_WORKER'] = 1;
+        $this->assertInstanceOf(ResponseRunner::class, $runtime->getRunner($application));
+    }
 }