diff --git a/bindinfo/handle.go b/bindinfo/handle.go
index 907b6e94ccde0..59919e2b5ad85 100644
--- a/bindinfo/handle.go
+++ b/bindinfo/handle.go
@@ -533,6 +533,15 @@ func (h *BindHandle) SetBindRecordStatus(originalSQL string, binding *Binding, n
 	return
 }
 
+// SetBindRecordStatusByDigest set a BindRecord's status to the storage and bind cache.
+func (h *BindHandle) SetBindRecordStatusByDigest(newStatus, sqlDigest string) (ok bool, err error) {
+	oldRecord, err := h.GetBindRecordBySQLDigest(sqlDigest)
+	if err != nil {
+		return false, err
+	}
+	return h.SetBindRecordStatus(oldRecord.OriginalSQL, nil, newStatus)
+}
+
 // GCBindRecord physically removes the deleted bind records in mysql.bind_info.
 func (h *BindHandle) GCBindRecord() (err error) {
 	h.bindInfo.Lock()
diff --git a/executor/bind.go b/executor/bind.go
index c5f254121a9bf..90272e6878620 100644
--- a/executor/bind.go
+++ b/executor/bind.go
@@ -63,6 +63,8 @@ func (e *SQLBindExec) Next(ctx context.Context, req *chunk.Chunk) error {
 		return e.reloadBindings()
 	case plannercore.OpSetBindingStatus:
 		return e.setBindingStatus()
+	case plannercore.OpSetBindingStatusByDigest:
+		return e.setBindingStatusByDigest()
 	default:
 		return errors.Errorf("unsupported SQL bind operation: %v", e.sqlBindOp)
 	}
@@ -119,6 +121,15 @@ func (e *SQLBindExec) setBindingStatus() error {
 	return err
 }
 
+func (e *SQLBindExec) setBindingStatusByDigest() error {
+	ok, err := domain.GetDomain(e.ctx).BindHandle().SetBindRecordStatusByDigest(e.newStatus, e.sqlDigest)
+	if err == nil && !ok {
+		warningMess := errors.New("There are no bindings can be set the status. Please check the SQL text")
+		e.ctx.GetSessionVars().StmtCtx.AppendWarning(warningMess)
+	}
+	return err
+}
+
 func (e *SQLBindExec) createSQLBind() error {
 	// For audit log, SQLBindExec execute "explain" statement internally, save and recover stmtctx
 	// is necessary to avoid 'create binding' been recorded as 'explain'.
diff --git a/infoschema/cluster_tables_test.go b/infoschema/cluster_tables_test.go
index 00892c95cfe9c..73488028a26ec 100644
--- a/infoschema/cluster_tables_test.go
+++ b/infoschema/cluster_tables_test.go
@@ -1028,3 +1028,34 @@ func TestBindingFromHistoryWithTiFlashBindable(t *testing.T) {
 	planDigest := tk.MustQuery(fmt.Sprintf("select plan_digest from information_schema.statements_summary where query_sample_text = '%s'", sql)).Rows()
 	tk.MustGetErrMsg(fmt.Sprintf("create binding from history using plan digest '%s'", planDigest[0][0]), "can't create binding for query with tiflash engine")
 }
+
+func TestSetBindingStatusBySQLDigest(t *testing.T) {
+	s := new(clusterTablesSuite)
+	s.store, s.dom = testkit.CreateMockStoreAndDomain(t)
+	s.rpcserver, s.listenAddr = s.setUpRPCService(t, "127.0.0.1:0", nil)
+	s.httpServer, s.mockAddr = s.setUpMockPDHTTPServer()
+	s.startTime = time.Now()
+	defer s.httpServer.Close()
+	defer s.rpcserver.Stop()
+	tk := s.newTestKitWithRoot(t)
+	require.NoError(t, tk.Session().Auth(&auth.UserIdentity{Username: "root", Hostname: "%"}, nil, nil))
+	tk.MustExec("use test")
+	tk.MustExec("drop table if exists t")
+	tk.MustExec("create table t(id int, a int, key(a))")
+	sql := "select /*+ ignore_index(t, a) */ * from t where t.a = 1"
+	tk.MustExec(sql)
+	planDigest := tk.MustQuery(fmt.Sprintf("select plan_digest from information_schema.cluster_statements_summary where query_sample_text = '%s'", sql)).Rows()
+	tk.MustExec(fmt.Sprintf("create global binding from history using plan digest '%s'", planDigest[0][0]))
+	sql = "select * from t where t.a = 1"
+	tk.MustExec(sql)
+	tk.MustQuery("select @@last_plan_from_binding").Check(testkit.Rows("1"))
+
+	sqlDigest := tk.MustQuery("show global bindings").Rows()
+	tk.MustExec(fmt.Sprintf("set binding disabled for sql digest '%s'", sqlDigest[0][9]))
+	tk.MustExec(sql)
+	tk.MustQuery("select @@last_plan_from_binding").Check(testkit.Rows("0"))
+	tk.MustExec(fmt.Sprintf("set binding enabled for sql digest '%s'", sqlDigest[0][9]))
+	tk.MustExec(sql)
+	tk.MustQuery("select @@last_plan_from_binding").Check(testkit.Rows("1"))
+	tk.MustGetErrMsg("set binding enabled for sql digest '2'", "can't find any binding for '2'")
+}
diff --git a/planner/core/common_plans.go b/planner/core/common_plans.go
index 8feb357745853..53aa657d2f9c0 100644
--- a/planner/core/common_plans.go
+++ b/planner/core/common_plans.go
@@ -252,6 +252,8 @@ const (
 	OpSetBindingStatus
 	// OpSQLBindDropByDigest is used to drop SQL binds by digest
 	OpSQLBindDropByDigest
+	// OpSetBindingStatusByDigest represents the operation to set SQL binding status by sql digest.
+	OpSetBindingStatusByDigest
 )
 
 // SQLBindPlan represents a plan for SQL bind.
diff --git a/planner/core/planbuilder.go b/planner/core/planbuilder.go
index 26508814523d2..238e2a687d758 100644
--- a/planner/core/planbuilder.go
+++ b/planner/core/planbuilder.go
@@ -1014,10 +1014,20 @@ func (b *PlanBuilder) buildDropBindPlan(v *ast.DropBindingStmt) (Plan, error) {
 }
 
 func (b *PlanBuilder) buildSetBindingStatusPlan(v *ast.SetBindingStmt) (Plan, error) {
-	p := &SQLBindPlan{
-		SQLBindOp:    OpSetBindingStatus,
-		NormdOrigSQL: parser.Normalize(utilparser.RestoreWithDefaultDB(v.OriginNode, b.ctx.GetSessionVars().CurrentDB, v.OriginNode.Text())),
-		Db:           utilparser.GetDefaultDB(v.OriginNode, b.ctx.GetSessionVars().CurrentDB),
+	var p *SQLBindPlan
+	if v.OriginNode != nil {
+		p = &SQLBindPlan{
+			SQLBindOp:    OpSetBindingStatus,
+			NormdOrigSQL: parser.Normalize(utilparser.RestoreWithDefaultDB(v.OriginNode, b.ctx.GetSessionVars().CurrentDB, v.OriginNode.Text())),
+			Db:           utilparser.GetDefaultDB(v.OriginNode, b.ctx.GetSessionVars().CurrentDB),
+		}
+	} else if v.SQLDigest != "" {
+		p = &SQLBindPlan{
+			SQLBindOp: OpSetBindingStatusByDigest,
+			SQLDigest: v.SQLDigest,
+		}
+	} else {
+		return nil, errors.New("sql digest is empty")
 	}
 	switch v.BindingStatusType {
 	case ast.BindingStatusTypeEnabled: