diff --git a/.changeset/kind-scissors-type.md b/.changeset/kind-scissors-type.md
new file mode 100644
index 00000000000..0886fdc7ced
--- /dev/null
+++ b/.changeset/kind-scissors-type.md
@@ -0,0 +1,5 @@
+---
+"@primer/react": patch
+---
+
+`Pagination`: Use `<button>` instead of `<span>` for disabled prev/next controls to improve accessibility
diff --git a/src/Pagination/Pagination.tsx b/src/Pagination/Pagination.tsx
index ab12d30e5d5..a193f4b1217 100644
--- a/src/Pagination/Pagination.tsx
+++ b/src/Pagination/Pagination.tsx
@@ -57,6 +57,18 @@ const Page = styled.a`
     border-color: transparent;
   }
 
+  &[aria-disabled],
+  &[aria-disabled]:hover {
+    color: ${get('colors.primer.fg.disabled')}; // check
+    cursor: default;
+    background-color: transparent;
+    border-color: transparent;
+    font-size: inherit;
+    font-family: inherit;
+    padding-top: inherit;
+    padding-bottom: inherit;
+  }
+
   &[aria-disabled],
   &[aria-disabled]:hover,
   &[role='presentation'],
diff --git a/src/Pagination/model.tsx b/src/Pagination/model.tsx
index 914ab52d24f..e8e80c7a682 100644
--- a/src/Pagination/model.tsx
+++ b/src/Pagination/model.tsx
@@ -148,7 +148,7 @@ export function buildComponentData(
       key = 'page-prev'
       content = 'Previous'
       if (page.disabled) {
-        Object.assign(props, {as: 'span', 'aria-disabled': 'true'})
+        Object.assign(props, {as: 'button', 'aria-disabled': 'true'})
       } else {
         Object.assign(props, {
           rel: 'prev',
@@ -163,7 +163,7 @@ export function buildComponentData(
       key = 'page-next'
       content = 'Next'
       if (page.disabled) {
-        Object.assign(props, {as: 'span', 'aria-disabled': 'true'})
+        Object.assign(props, {as: 'button', 'aria-disabled': 'true'})
       } else {
         Object.assign(props, {
           rel: 'next',