diff --git a/Lib/test/test_perf_profiler.py b/Lib/test/test_perf_profiler.py
index 1e74990878007a..6f1fd8d38e4ea0 100644
--- a/Lib/test/test_perf_profiler.py
+++ b/Lib/test/test_perf_profiler.py
@@ -47,6 +47,7 @@ def tearDown(self) -> None:
         for file in files_to_delete:
             file.unlink()
 
+    @unittest.skipIf(support.check_bolt_optimized, "fails on BOLT instrumented binaries")
     def test_trampoline_works(self):
         code = """if 1:
                 def foo():
@@ -100,6 +101,7 @@ def baz():
                 "Address should contain only hex characters",
             )
 
+    @unittest.skipIf(support.check_bolt_optimized, "fails on BOLT instrumented binaries")
     def test_trampoline_works_with_forks(self):
         code = """if 1:
                 import os, sys
@@ -160,6 +162,7 @@ def baz():
         self.assertIn(f"py::bar_fork:{script}", child_perf_file_contents)
         self.assertIn(f"py::baz_fork:{script}", child_perf_file_contents)
 
+    @unittest.skipIf(support.check_bolt_optimized, "fails on BOLT instrumented binaries")
     def test_sys_api(self):
         code = """if 1:
                 import sys