diff --git a/Objects/typeobject.c b/Objects/typeobject.c
index 1cb53516a9ae76..0b38069151f432 100644
--- a/Objects/typeobject.c
+++ b/Objects/typeobject.c
@@ -116,11 +116,13 @@ type_from_ref(PyObject *ref)
 
 /* helpers for for static builtin types */
 
+#ifndef NDEBUG
 static inline int
 static_builtin_index_is_set(PyTypeObject *self)
 {
     return self->tp_subclasses != NULL;
 }
+#endif
 
 static inline size_t
 static_builtin_index_get(PyTypeObject *self)