diff --git a/Python/pylifecycle.c b/Python/pylifecycle.c
index 2d219a4a3a8b0d..ab5a6767864dc5 100644
--- a/Python/pylifecycle.c
+++ b/Python/pylifecycle.c
@@ -1286,10 +1286,8 @@ finalize_interp_clear(PyThreadState *tstate)
     /* Clear interpreter state and all thread states */
     PyInterpreterState_Clear(tstate->interp);
 
-    /* Trigger a GC collection on subinterpreters*/
-    if (!is_main_interp) {
-        _PyGC_CollectNoFail();
-    }
+    /* Last explicit GC collection */
+    _PyGC_CollectNoFail();
 
     /* Clear all loghooks */
     /* Both _PySys_Audit function and users still need PyObject, such as tuple.