diff --git a/Misc/NEWS.d/next/Build/2022-08-26-11-09-11.gh-issue-84461.Nsdn_R.rst b/Misc/NEWS.d/next/Build/2022-08-26-11-09-11.gh-issue-84461.Nsdn_R.rst
new file mode 100644
index 00000000000000..134e9645159a69
--- /dev/null
+++ b/Misc/NEWS.d/next/Build/2022-08-26-11-09-11.gh-issue-84461.Nsdn_R.rst
@@ -0,0 +1,3 @@
+``wasm32-emscripten`` platform no longer builds :mod:`resource` module,
+:func:`~os.getresuid`, :func:`~os.getresgid`, and their setters. The APIs
+are stubs and not functional.
diff --git a/Tools/wasm/config.site-wasm32-emscripten b/Tools/wasm/config.site-wasm32-emscripten
index a31d60d05dd770..b695a7bf8f04da 100644
--- a/Tools/wasm/config.site-wasm32-emscripten
+++ b/Tools/wasm/config.site-wasm32-emscripten
@@ -49,6 +49,10 @@ ac_cv_func_geteuid=no
 ac_cv_func_getegid=no
 ac_cv_func_seteuid=no
 ac_cv_func_setegid=no
+ac_cv_func_getresuid=no
+ac_cv_func_getresgid=no
+ac_cv_func_setresuid=no
+ac_cv_func_setresgid=no
 
 # Syscalls not implemented in emscripten
 # [Errno 52] Function not implemented
diff --git a/configure b/configure
index 1801f806ae137f..758806a6c6fb11 100755
--- a/configure
+++ b/configure
@@ -25544,6 +25544,7 @@ case $ac_sys_system in #(
     py_cv_module_nis=n/a
     py_cv_module_ossaudiodev=n/a
     py_cv_module_pwd=n/a
+    py_cv_module_resource=n/a
     py_cv_module_spwd=n/a
     py_cv_module_syslog=n/a
     py_cv_module_=n/a
@@ -25554,7 +25555,6 @@ case $ac_sys_system in #(
 
 
     py_cv_module_fcntl=n/a
-    py_cv_module_resource=n/a
     py_cv_module_readline=n/a
     py_cv_module_termios=n/a
     py_cv_module_=n/a
@@ -25569,7 +25569,6 @@ case $ac_sys_system in #(
     py_cv_module__ctypes_test=n/a
     py_cv_module_fcntl=n/a
     py_cv_module_mmap=n/a
-    py_cv_module_resource=n/a
     py_cv_module_termios=n/a
     py_cv_module_=n/a
 
diff --git a/configure.ac b/configure.ac
index bb9fec07242f8e..9ba5553cf7d0da 100644
--- a/configure.ac
+++ b/configure.ac
@@ -7048,6 +7048,7 @@ AS_CASE([$ac_sys_system],
     dnl curses and tkinter user interface are not available.
     dnl dbm and gdbm aren't available, too.
     dnl Emscripten and WASI provide only stubs for pwd, grp APIs.
+    dnl resource functions (get/setrusage) are stubs, too.
     PY_STDLIB_MOD_SET_NA(
       [_curses],
       [_curses_panel],
@@ -7063,6 +7064,7 @@ AS_CASE([$ac_sys_system],
       [nis],
       [ossaudiodev],
       [pwd],
+      [resource],
       [spwd],
       [syslog],
     )
@@ -7071,7 +7073,6 @@ AS_CASE([$ac_sys_system],
         dnl These modules are not particularly useful in browsers.
         PY_STDLIB_MOD_SET_NA(
           [fcntl],
-          [resource],
           [readline],
           [termios],
         )
@@ -7083,7 +7084,6 @@ AS_CASE([$ac_sys_system],
           [_ctypes_test],
           [fcntl],
           [mmap],
-          [resource],
           [termios],
         )
       ]