diff --git a/Lib/test/test_ctypes/test_bitfields.py b/Lib/test/test_ctypes/test_bitfields.py
index dad71a0ba7ee4a..af2380e28b8736 100644
--- a/Lib/test/test_ctypes/test_bitfields.py
+++ b/Lib/test/test_ctypes/test_bitfields.py
@@ -40,8 +40,6 @@ def test_ints(self):
                 setattr(b, name, i)
                 self.assertEqual(getattr(b, name), func(byref(b), name.encode('ascii')))
 
-    # bpo-46913: _ctypes/cfield.c h_get() has an undefined behavior
-    @support.skip_if_sanitizer(ub=True)
     def test_shorts(self):
         b = BITS()
         name = "M"
diff --git a/Misc/NEWS.d/next/Core and Builtins/2022-09-19-06-42-20.gh-issue-96821.jrmhsw.rst b/Misc/NEWS.d/next/Core and Builtins/2022-09-19-06-42-20.gh-issue-96821.jrmhsw.rst
new file mode 100644
index 00000000000000..e49e73b1a0bb00
--- /dev/null
+++ b/Misc/NEWS.d/next/Core and Builtins/2022-09-19-06-42-20.gh-issue-96821.jrmhsw.rst	
@@ -0,0 +1 @@
+Fix undefined behaviour in ``_ctypes/cfield.c``.
diff --git a/Modules/_ctypes/cfield.c b/Modules/_ctypes/cfield.c
index 13ed8b7eda6555..060ee86fb700fe 100644
--- a/Modules/_ctypes/cfield.c
+++ b/Modules/_ctypes/cfield.c
@@ -412,21 +412,23 @@ get_ulonglong(PyObject *v, unsigned long long *p)
 #define NUM_BITS(x) ((x) >> 16)
 
 /* Doesn't work if NUM_BITS(size) == 0, but it never happens in SET() call. */
-#define BIT_MASK(type, size) (((((type)1 << (NUM_BITS(size) - 1)) - 1) << 1) + 1)
+#define BIT_MASK(type, size) \
+    (assert(NUM_BITS(size) > 0), \
+        (((((type)1 << (NUM_BITS(size) - 1)) - 1) << 1) + 1))
 
 /* This macro CHANGES the first parameter IN PLACE. For proper sign handling,
    we must first shift left, then right.
 */
 #define GET_BITFIELD(v, size)                                           \
     if (NUM_BITS(size)) {                                               \
-        v <<= (sizeof(v)*8 - LOW_BIT(size) - NUM_BITS(size));           \
+        v *= 1ULL << (sizeof(v)*8 - LOW_BIT(size) - NUM_BITS(size));    \
         v >>= (sizeof(v)*8 - NUM_BITS(size));                           \
     }
 
 /* This macro RETURNS the first parameter with the bit field CHANGED. */
 #define SET(type, x, v, size)                                                 \
     (NUM_BITS(size) ?                                                   \
-     ( ( (type)x & ~(BIT_MASK(type, size) << LOW_BIT(size)) ) | ( ((type)v & BIT_MASK(type, size)) << LOW_BIT(size) ) ) \
+     (type) ( ( (type)x & ~(BIT_MASK(type, size) * (1ULL << LOW_BIT(size))) ) | ( ((type)v & BIT_MASK(type, size)) * (1ULL << LOW_BIT(size) )) ) \
      : (type)v)
 
 #if SIZEOF_SHORT == 2