diff --git a/Makefile.PL b/Makefile.PL
index 0cbebc5d..b24f3343 100644
--- a/Makefile.PL
+++ b/Makefile.PL
@@ -306,6 +306,7 @@ sub find_openssl_prefix {
 
     my @guesses = (
 	'/home/linuxbrew/.linuxbrew/opt/openssl/bin/openssl' => '/home/linuxbrew/.linuxbrew/opt/openssl', # LinuxBrew openssl
+	'/opt/homebrew/opt/openssl/bin/openssl' => '/opt/homebrew/opt/openssl', # macOS ARM homebrew
 	'/usr/local/opt/openssl/bin/openssl' => '/usr/local/opt/openssl', # OSX homebrew openssl
 	'/usr/local/bin/openssl'         => '/usr/local', # OSX homebrew openssl
 	'/opt/local/bin/openssl'         => '/opt/local', # Macports openssl