diff --git a/Refit.Tests/AuthenticatedClientHandlerTests.cs b/Refit.Tests/AuthenticatedClientHandlerTests.cs
index 7dce85749..98f02379e 100644
--- a/Refit.Tests/AuthenticatedClientHandlerTests.cs
+++ b/Refit.Tests/AuthenticatedClientHandlerTests.cs
@@ -4,8 +4,11 @@
 using System.Net.Http;
 using System.Text;
 using System.Threading.Tasks;
+
 using Refit; // for the code gen
+
 using RichardSzalay.MockHttp;
+
 using Xunit;
 
 namespace Refit.Tests;
@@ -49,6 +52,12 @@ public interface IInheritedAuthenticatedServiceWithHeaders : IAuthenticatedServi
         Task<string> GetInheritedThing();
     }
 
+    public interface IInheritedAuthenticatedServiceWithHeadersCRLF : IAuthenticatedServiceWithHeaders
+    {
+        [Get("/get-inherited-thing\r\n\r\nGET /smuggled")]
+        Task<string> GetInheritedThing();
+    }
+
     [Headers("Authorization: Bearer")]
     public interface IAuthenticatedServiceWithHeaders
     {
@@ -347,4 +356,30 @@ public async void AuthentictedMethodFromInheritedClassWithHeadersAttributeUsesAu
 
         Assert.Equal("Ok", result);
     }
+
+    [Fact]
+    public async void AuthentictedMethodFromInheritedClassWithHeadersAttributeUsesAuth_WithCRLFCheck()
+    {
+        var handler = new MockHttpMessageHandler();
+        var settings = new RefitSettings()
+        {
+            AuthorizationHeaderValueGetter = (_, __) => Task.FromResult("tokenValue"),
+            HttpMessageHandlerFactory = () => handler,
+        };
+
+        handler
+            .Expect(HttpMethod.Get, "http://api/get-inherited-thing")
+            .WithHeaders("Authorization", "Bearer tokenValue")
+            .Respond("text/plain", "Ok");
+
+        await Assert.ThrowsAsync<ArgumentException>(async () =>
+        {
+            var fixture = RestService.For<IInheritedAuthenticatedServiceWithHeadersCRLF>(
+                    "http://api",
+                    settings
+                );
+
+            var result = await fixture.GetInheritedThing();
+        });
+    }
 }
diff --git a/Refit/RequestBuilderImplementation.cs b/Refit/RequestBuilderImplementation.cs
index 807cafb79..2882d3ed6 100644
--- a/Refit/RequestBuilderImplementation.cs
+++ b/Refit/RequestBuilderImplementation.cs
@@ -977,7 +977,7 @@ static void AddHeadersToRequest(Dictionary<string, string?>? headersToAdd, HttpR
             // sure we have an HttpContent object to add them to,
             // provided the HttpClient will allow it for the method
             if (ret.Content == null && !IsBodyless(ret.Method))
-                ret.Content = new ByteArrayContent(Array.Empty<byte>());
+                ret.Content = new ByteArrayContent([]);
 
             foreach (var header in headersToAdd)
             {
@@ -1335,6 +1335,10 @@ static void SetHeader(HttpRequestMessage request, string name, string? value)
             if (value == null)
                 return;
 
+            // CRLF injection protection
+            name = EnsureSafe(name);
+            value = EnsureSafe(value);
+
             var added = request.Headers.TryAddWithoutValidation(name, value);
 
             // Don't even bother trying to add the header as a content header
@@ -1345,6 +1349,14 @@ static void SetHeader(HttpRequestMessage request, string name, string? value)
             }
         }
 
+        static string EnsureSafe(string value)
+        {
+            // Remove CR and LF characters
+#pragma warning disable CA1307 // Specify StringComparison for clarity
+            return value.Replace("\r", string.Empty).Replace("\n", string.Empty);
+#pragma warning restore CA1307 // Specify StringComparison for clarity
+        }
+
         static bool IsBodyless(HttpMethod method) => method == HttpMethod.Get || method == HttpMethod.Head;
     }
 }
diff --git a/Refit/RestMethodInfo.cs b/Refit/RestMethodInfo.cs
index a22dd5262..901dfc338 100644
--- a/Refit/RestMethodInfo.cs
+++ b/Refit/RestMethodInfo.cs
@@ -259,6 +259,12 @@ static void VerifyUrlPathIsSane(string relativePath)
                 throw new ArgumentException(
                     $"URL path {relativePath} must start with '/' and be of the form '/foo/bar/baz'"
                 );
+
+            // CRLF injection protection
+            if (relativePath.Contains("\r") || relativePath.Contains("\n"))
+                throw new ArgumentException(
+                    $"URL path {relativePath} must not contain CR or LF characters"
+                );
         }
 
         static Dictionary<int, RestMethodParameterInfo> BuildParameterMap(