diff --git a/compiler/rustc_middle/src/ty/util.rs b/compiler/rustc_middle/src/ty/util.rs
index fc03ad52b4bf1..2797f2fcdb72e 100644
--- a/compiler/rustc_middle/src/ty/util.rs
+++ b/compiler/rustc_middle/src/ty/util.rs
@@ -1394,8 +1394,10 @@ impl<'tcx> Ty<'tcx> {
 
                 // This doesn't depend on regions, so try to minimize distinct
                 // query keys used.
-                let erased = tcx.normalize_erasing_regions(typing_env, query_ty);
-                tcx.has_significant_drop_raw(typing_env.as_query_input(erased))
+                // FIX: Use try_normalize to avoid crashing. If it fails, return true.
+                tcx.try_normalize_erasing_regions(typing_env, query_ty)
+                    .map(|erased| tcx.has_significant_drop_raw(typing_env.as_query_input(erased)))
+                    .unwrap_or(true)
             }
         }
     }
diff --git a/tests/ui/associated-types/normalization-ice-issue-149746.rs b/tests/ui/associated-types/normalization-ice-issue-149746.rs
new file mode 100644
index 0000000000000..8932d321b7e5b
--- /dev/null
+++ b/tests/ui/associated-types/normalization-ice-issue-149746.rs
@@ -0,0 +1,17 @@
+//@ edition: 2015..2021
+#![warn(rust_2021_incompatible_closure_captures)]
+trait Owner { type Ty<T: FnMut()>; }
+impl Owner for () { type Ty<T: FnMut()> = T; }
+pub struct Warns<T> {
+    _significant_drop: <() as Owner>::Ty<T>,
+    //~^ ERROR expected a `FnMut()` closure, found `T`
+    field: String,
+}
+pub fn test<T>(w: Warns<T>) {
+    //~^ ERROR expected a `FnMut()` closure, found `T`
+    _ = || w.field
+    //~^ ERROR expected a `FnMut()` closure, found `T`
+    //~| ERROR expected a `FnMut()` closure, found `T`
+    //~| WARN: changes to closure capture in Rust 2021 will affect drop order
+}
+fn main() {}
diff --git a/tests/ui/associated-types/normalization-ice-issue-149746.stderr b/tests/ui/associated-types/normalization-ice-issue-149746.stderr
new file mode 100644
index 0000000000000..7f983d6e14ae2
--- /dev/null
+++ b/tests/ui/associated-types/normalization-ice-issue-149746.stderr
@@ -0,0 +1,80 @@
+error[E0277]: expected a `FnMut()` closure, found `T`
+  --> $DIR/normalization-ice-issue-149746.rs:6:24
+   |
+LL |     _significant_drop: <() as Owner>::Ty<T>,
+   |                        ^^^^^^^^^^^^^^^^^^^^ expected an `FnMut()` closure, found `T`
+   |
+   = note: wrap the `T` in a closure with no arguments: `|| { /* code */ }`
+note: required by a bound in `Owner::Ty`
+  --> $DIR/normalization-ice-issue-149746.rs:3:26
+   |
+LL | trait Owner { type Ty<T: FnMut()>; }
+   |                          ^^^^^^^ required by this bound in `Owner::Ty`
+help: consider restricting type parameter `T` with trait `FnMut`
+   |
+LL | pub struct Warns<T: FnMut()> {
+   |                   +++++++++
+
+warning: changes to closure capture in Rust 2021 will affect drop order
+  --> $DIR/normalization-ice-issue-149746.rs:12:9
+   |
+LL |     _ = || w.field
+   |         ^^ -------
+   |            |     |
+   |            |     in Rust 2018, `w` is dropped here, but in Rust 2021, only `w.field` will be dropped here as part of the closure
+   |            in Rust 2018, this closure captures all of `w`, but in Rust 2021, it will only capture `w.field`
+   |
+   = note: for more information, see <https://doc.rust-lang.org/edition-guide/rust-2021/disjoint-capture-in-closures.html>
+note: the lint level is defined here
+  --> $DIR/normalization-ice-issue-149746.rs:2:9
+   |
+LL | #![warn(rust_2021_incompatible_closure_captures)]
+   |         ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^
+help: add a dummy let to cause `w` to be fully captured
+   |
+LL |     _ = || { let _ = &w; w.field }
+   |            +++++++++++++         +
+
+error[E0277]: expected a `FnMut()` closure, found `T`
+  --> $DIR/normalization-ice-issue-149746.rs:12:9
+   |
+LL |     _ = || w.field
+   |         ^^^^^^^^^^ expected an `FnMut()` closure, found `T`
+   |
+   = note: wrap the `T` in a closure with no arguments: `|| { /* code */ }`
+note: required by a bound in `Owner::Ty`
+  --> $DIR/normalization-ice-issue-149746.rs:3:26
+   |
+LL | trait Owner { type Ty<T: FnMut()>; }
+   |                          ^^^^^^^ required by this bound in `Owner::Ty`
+
+error[E0277]: expected a `FnMut()` closure, found `T`
+  --> $DIR/normalization-ice-issue-149746.rs:10:16
+   |
+LL | pub fn test<T>(w: Warns<T>) {
+   |                ^ expected an `FnMut()` closure, found `T`
+   |
+   = note: wrap the `T` in a closure with no arguments: `|| { /* code */ }`
+note: required by a bound in `Owner::Ty`
+  --> $DIR/normalization-ice-issue-149746.rs:3:26
+   |
+LL | trait Owner { type Ty<T: FnMut()>; }
+   |                          ^^^^^^^ required by this bound in `Owner::Ty`
+
+error[E0277]: expected a `FnMut()` closure, found `T`
+  --> $DIR/normalization-ice-issue-149746.rs:12:9
+   |
+LL |     _ = || w.field
+   |         ^^^^^^^^^^ expected an `FnMut()` closure, found `T`
+   |
+   = note: wrap the `T` in a closure with no arguments: `|| { /* code */ }`
+note: required by a bound in `Owner::Ty`
+  --> $DIR/normalization-ice-issue-149746.rs:3:26
+   |
+LL | trait Owner { type Ty<T: FnMut()>; }
+   |                          ^^^^^^^ required by this bound in `Owner::Ty`
+   = note: duplicate diagnostic emitted due to `-Z deduplicate-diagnostics=no`
+
+error: aborting due to 4 previous errors; 1 warning emitted
+
+For more information about this error, try `rustc --explain E0277`.