diff --git a/sdcm/sct_events/filters.py b/sdcm/sct_events/filters.py
index 777cc46e33..1c9bd26cc2 100644
--- a/sdcm/sct_events/filters.py
+++ b/sdcm/sct_events/filters.py
@@ -23,7 +23,7 @@
 class DbEventsFilter(BaseFilter):
     def __init__(self,
                  db_event: Union[LogEventProtocol, Type[LogEventProtocol]],
-                 line: Optional[str] = None,
+                 line: Optional[Union[str, re.Pattern]] = None,
                  node: Optional = None,
                  extra_time_to_expiration: Optional[int] = 0):
         super().__init__()
@@ -31,8 +31,22 @@ def __init__(self,
         self.filter_type = db_event.type
         self.filter_line = line
         self.filter_node = str(node.name if hasattr(node, "name") else node) if node else None
-
         self.extra_time_to_expiration = extra_time_to_expiration
+        self.regex = None  # Initialize regex to None
+        self.regex_flags = 0  # Initialize regex_flags to default value
+        if isinstance(line, re.Pattern):
+            self.regex = line.pattern
+            self.regex_flags = line.flags
+        elif isinstance(line, str):
+            self.regex = line
+            self.regex_flags = re.MULTILINE | re.DOTALL
+
+    @cached_property
+    def _regex(self):
+        try:
+            return self.regex and re.compile(self.regex, self.regex_flags)
+        except Exception as exc:  # noqa: BLE001
+            raise ValueError(f'Compilation of the regexp "{self.regex}" failed with error: {exc}') from None
 
     def eval_filter(self, event: LogEventProtocol) -> bool:
         if not isinstance(event, LogEventProtocol):
@@ -43,8 +57,9 @@ def eval_filter(self, event: LogEventProtocol) -> bool:
 
         result = bool(self.filter_type) and self.filter_type == event.type
 
-        if self.filter_line:
-            result &= self.filter_line in (getattr(event, "line", "") or "")
+        if self._regex:
+            event_line = (getattr(event, "line", "") or "")
+            result &= (self._regex.search(event_line) is not None)
 
         if self.filter_node:
             result &= self.filter_node in (getattr(event, "node", "") or "").split()
@@ -61,8 +76,8 @@ def msgfmt(self) -> str:
         output = ['{0.base}']
         if self.filter_type:
             output.append('type={0.filter_type}')
-        if self.filter_line:
-            output.append('line={0.filter_line}')
+        if self._regex:
+            output.append(f'line={self._regex.pattern}')
         if self.filter_node:
             output.append('node={0.filter_node}')
         return '(' + (' '.join(output)) + ')'
diff --git a/sdcm/sct_events/group_common_events.py b/sdcm/sct_events/group_common_events.py
index 89bf3de01c..c52c644e24 100644
--- a/sdcm/sct_events/group_common_events.py
+++ b/sdcm/sct_events/group_common_events.py
@@ -10,7 +10,6 @@
 # See LICENSE for more details.
 #
 # Copyright (c) 2020 ScyllaDB
-
 from contextlib import contextmanager, ExitStack, ContextDecorator
 from functools import wraps
 from typing import ContextManager, Callable, Sequence
@@ -96,14 +95,18 @@ def ignore_topology_change_coordinator_errors():
             #   Therefore, it is OK to ignore this particular error until a proper fix is merged.
             stack.enter_context(DbEventsFilter(
                 db_event=DatabaseLogEvent.DATABASE_ERROR,
-                line="raft_topology - topology change coordinator fiber got error exceptions::unavailable_exception"
-                     " (Cannot achieve consistency level for cl ALL.",
+                line=r".*raft_topology - topology change coordinator fiber got error exceptions::unavailable_exception "
+                     r"\(Cannot achieve consistency level for cl ALL\.",
+            ))
+            stack.enter_context(DbEventsFilter(
+                db_event=DatabaseLogEvent.RUNTIME_ERROR,
+                line=r".*raft_topology - topology change coordinator fiber got error std::runtime_error"
+                     r" \(raft topology: exec_global_command\(barrier\) failed with seastar::rpc::closed_erro"
+                     r"r \(connection is closed\)\)"
             ))
             stack.enter_context(DbEventsFilter(
                 db_event=DatabaseLogEvent.RUNTIME_ERROR,
-                line="raft_topology - topology change coordinator fiber got error std::runtime_error"
-                     " (raft topology: exec_global_command(barrier) failed with seastar::rpc::closed_error"
-                     " (connection is closed))",
+                line=r".*raft_topology - drain rpc failed, proceed to fence old writes:.*connection is closed",
             ))
         yield
 
diff --git a/unit_tests/test_sct_events_filters.py b/unit_tests/test_sct_events_filters.py
index a6d12ffd91..f4db452114 100644
--- a/unit_tests/test_sct_events_filters.py
+++ b/unit_tests/test_sct_events_filters.py
@@ -57,6 +57,29 @@ def test_eval_filter_type_with_line_and_node(self):
         self.assertFalse(db_events_filter.eval_filter(event2))
         self.assertFalse(db_events_filter.eval_filter(event3))
 
+    def test_eval_filter_type_with_regex_line(self):
+        regex = re.compile(r".*raft_topology - drain rpc failed, proceed to fence "
+                           r"old writes:.*connection is closed")
+        db_events_filter = DbEventsFilter(db_event=DatabaseLogEvent.RUNTIME_ERROR, line=regex)
+        event1 = DatabaseLogEvent.RUNTIME_ERROR().add_info(
+            node="node1",
+            line="raft_topology - drain rpc failed, proceed to fence old writes: connection is closed",
+            line_number=1
+        )
+        event2 = event1.clone().add_info(
+            node="node2",
+            line="unrelated log entry",
+            line_number=1
+        )
+        event3 = DatabaseLogEvent.NO_SPACE_ERROR().add_info(
+            node="node1",
+            line="raft_topology - drain rpc failed, proceed to fence old writes: connection is closed",
+            line_number=1
+        )
+        self.assertTrue(db_events_filter.eval_filter(event1))
+        self.assertFalse(db_events_filter.eval_filter(event2))
+        self.assertFalse(db_events_filter.eval_filter(event3))
+
 
 class TestEventsFilter(unittest.TestCase):
     def test_event_class_and_regex_none(self):