diff --git a/Marlin/src/inc/SanityCheck.h b/Marlin/src/inc/SanityCheck.h
index ccbf5c670590..27629c5a7da0 100644
--- a/Marlin/src/inc/SanityCheck.h
+++ b/Marlin/src/inc/SanityCheck.h
@@ -3348,10 +3348,59 @@ static_assert(NUM_SERVOS <= NUM_SERVO_PLUGS, "NUM_SERVOS (or some servo index) i
   #error "MARKFORGED requires both X and Y to use sensorless homing if either one does."
 #endif
 
+// TMC Hybrid Threshold
+#if ENABLED(HYBRID_THRESHOLD)
+  #if !STEALTHCHOP_ENABLED
+    #error "Enable STEALTHCHOP_(XY|Z|E) to use HYBRID_THRESHOLD."
+  #elif defined(X_HYBRID_THRESHOLD) && X_HYBRID_THRESHOLD == 0
+    #error "X_HYBRID_THRESHOLD must be greater than 0."
+  #elif defined(X2_HYBRID_THRESHOLD) && X2_HYBRID_THRESHOLD == 0
+    #error "X2_HYBRID_THRESHOLD must be greater than 0."
+  #elif defined(Y_HYBRID_THRESHOLD) && Y_HYBRID_THRESHOLD == 0
+    #error "Y_HYBRID_THRESHOLD must be greater than 0."
+  #elif defined(Y2_HYBRID_THRESHOLD) && Y2_HYBRID_THRESHOLD == 0
+    #error "Y2_HYBRID_THRESHOLD must be greater than 0."
+  #elif defined(Z_HYBRID_THRESHOLD) && Z_HYBRID_THRESHOLD == 0
+    #error "Z_HYBRID_THRESHOLD must be greater than 0."
+  #elif defined(Z2_HYBRID_THRESHOLD) && Z2_HYBRID_THRESHOLD == 0
+    #error "Z2_HYBRID_THRESHOLD must be greater than 0."
+  #elif defined(Z3_HYBRID_THRESHOLD) && Z3_HYBRID_THRESHOLD == 0
+    #error "Z3_HYBRID_THRESHOLD must be greater than 0."
+  #elif defined(Z4_HYBRID_THRESHOLD) && Z4_HYBRID_THRESHOLD == 0
+    #error "Z4_HYBRID_THRESHOLD must be greater than 0."
+  #elif defined(I_HYBRID_THRESHOLD) && I_HYBRID_THRESHOLD == 0
+    #error "I_HYBRID_THRESHOLD must be greater than 0."
+  #elif defined(J_HYBRID_THRESHOLD) && J_HYBRID_THRESHOLD == 0
+    #error "J_HYBRID_THRESHOLD must be greater than 0."
+  #elif defined(K_HYBRID_THRESHOLD) && K_HYBRID_THRESHOLD == 0
+    #error "K_HYBRID_THRESHOLD must be greater than 0."
+  #elif defined(U_HYBRID_THRESHOLD) && U_HYBRID_THRESHOLD == 0
+    #error "U_HYBRID_THRESHOLD must be greater than 0."
+  #elif defined(V_HYBRID_THRESHOLD) && V_HYBRID_THRESHOLD == 0
+    #error "V_HYBRID_THRESHOLD must be greater than 0."
+  #elif defined(W_HYBRID_THRESHOLD) && W_HYBRID_THRESHOLD == 0
+    #error "W_HYBRID_THRESHOLD must be greater than 0."
+  #elif defined(E0_HYBRID_THRESHOLD) && E0_HYBRID_THRESHOLD == 0
+    #error "E0_HYBRID_THRESHOLD must be greater than 0."
+  #elif defined(E1_HYBRID_THRESHOLD) && E1_HYBRID_THRESHOLD == 0
+    #error "E1_HYBRID_THRESHOLD must be greater than 0."
+  #elif defined(E2_HYBRID_THRESHOLD) && E2_HYBRID_THRESHOLD == 0
+    #error "E2_HYBRID_THRESHOLD must be greater than 0."
+  #elif defined(E3_HYBRID_THRESHOLD) && E3_HYBRID_THRESHOLD == 0
+    #error "E3_HYBRID_THRESHOLD must be greater than 0."
+  #elif defined(E4_HYBRID_THRESHOLD) && E4_HYBRID_THRESHOLD == 0
+    #error "E4_HYBRID_THRESHOLD must be greater than 0."
+  #elif defined(E5_HYBRID_THRESHOLD) && E5_HYBRID_THRESHOLD == 0
+    #error "E5_HYBRID_THRESHOLD must be greater than 0."
+  #elif defined(E6_HYBRID_THRESHOLD) && E6_HYBRID_THRESHOLD == 0
+    #error "E6_HYBRID_THRESHOLD must be greater than 0."
+  #elif defined(E7_HYBRID_THRESHOLD) && E7_HYBRID_THRESHOLD == 0
+    #error "E7_HYBRID_THRESHOLD must be greater than 0."
+  #endif
+#endif // HYBRID_THRESHOLD
+
 // Other TMC feature requirements
-#if ENABLED(HYBRID_THRESHOLD) && !STEALTHCHOP_ENABLED
-  #error "Enable STEALTHCHOP_(XY|Z|E) to use HYBRID_THRESHOLD."
-#elif ENABLED(SENSORLESS_HOMING) && !HAS_STALLGUARD
+#if ENABLED(SENSORLESS_HOMING) && !HAS_STALLGUARD
   #error "SENSORLESS_HOMING requires TMC2130, TMC2160, TMC2209, TMC2660, or TMC5160 stepper drivers."
 #elif ENABLED(SENSORLESS_PROBING) && !HAS_STALLGUARD
   #error "SENSORLESS_PROBING requires TMC2130, TMC2160, TMC2209, TMC2660, or TMC5160 stepper drivers."