diff --git a/bio/ngsbits/sampleancestry/environment.linux-64.pin.txt b/bio/ngsbits/sampleancestry/environment.linux-64.pin.txt
new file mode 100644
index 00000000000..9e396b084a8
--- /dev/null
+++ b/bio/ngsbits/sampleancestry/environment.linux-64.pin.txt
@@ -0,0 +1,166 @@
+# This file may be used to create an environment using:
+# $ conda create --name <env> --file <this file>
+# platform: linux-64
+# created-by: conda 24.9.2
+@EXPLICIT
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+https://conda.anaconda.org/conda-forge/linux-64/numpy-2.1.3-py312h58c1407_0.conda#dfdbc12e6d81889ba4c494a23f23eba8
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+https://conda.anaconda.org/conda-forge/linux-64/gstreamer-1.24.7-hf3bb09a_0.conda#c78bc4ef0afb3cd2365d9973c71fc876
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+https://conda.anaconda.org/conda-forge/linux-64/matplotlib-base-3.9.2-py312hd3ec401_2.conda#2380c9ba933ffaac9ad16d8eac8e3318
+https://conda.anaconda.org/conda-forge/linux-64/pulseaudio-client-17.0-hb77b528_0.conda#07f45f1be1c25345faddb8db0de8039b
+https://conda.anaconda.org/conda-forge/linux-64/qt-main-5.15.15-h374914d_0.conda#26e8b00e73c114c9b787d36edcbf4424
+https://conda.anaconda.org/bioconda/linux-64/ngs-bits-2024_11-py312hd80e9a6_0.tar.bz2#9b5b78cc9cc044f7539953d991e12daa
diff --git a/bio/ngsbits/sampleancestry/environment.yaml b/bio/ngsbits/sampleancestry/environment.yaml
new file mode 100644
index 00000000000..2e3de587389
--- /dev/null
+++ b/bio/ngsbits/sampleancestry/environment.yaml
@@ -0,0 +1,6 @@
+channels:
+  - conda-forge
+  - bioconda
+  - nodefaults
+dependencies:
+  - ngs-bits=2024_11
diff --git a/bio/ngsbits/sampleancestry/meta.yaml b/bio/ngsbits/sampleancestry/meta.yaml
new file mode 100644
index 00000000000..bd70b883cdc
--- /dev/null
+++ b/bio/ngsbits/sampleancestry/meta.yaml
@@ -0,0 +1,13 @@
+name: NGS-bits SampleAncestry
+url: https://github.com/imgag/ngs-bits/blob/master/doc/tools/SampleAncestry/index.md
+description: Estimates the ancestry of a sample based on variants.
+authors:
+  - Thibault Dayris
+input:
+  - Path to one or multiple VCF file(s).
+output:
+  - Path to results table (TSV)
+params:
+  - extra: Optional parameters besides IO
+notes: |
+  To estimate ancestry, the input VCF file must have enough variants AND variants that overlaps known human variants ancestry.
diff --git a/bio/ngsbits/sampleancestry/test/Snakefile b/bio/ngsbits/sampleancestry/test/Snakefile
new file mode 100644
index 00000000000..5b15bd9a07c
--- /dev/null
+++ b/bio/ngsbits/sampleancestry/test/Snakefile
@@ -0,0 +1,13 @@
+rule test_ngsbits_sampleancestry:
+    input:
+        # Either a single VCF or a list of VCF files
+        "sample.vcf",
+    output:
+        "ancestry.tsv",
+    threads: 1
+    log:
+        "ancestry.log",
+    params:
+        extra="-min_snps 4 -build hg19",
+    wrapper:
+        "master/bio/ngsbits/sampleancestry"
diff --git a/bio/ngsbits/sampleancestry/test/sample.vcf b/bio/ngsbits/sampleancestry/test/sample.vcf
new file mode 100644
index 00000000000..16a571c2c56
--- /dev/null
+++ b/bio/ngsbits/sampleancestry/test/sample.vcf
@@ -0,0 +1,11 @@
+##fileformat=VCFv4.0
+##INFO=<ID=AF_AFR,Number=1,Type=String,Description="no description available">
+##INFO=<ID=AF_EAS,Number=1,Type=String,Description="no description available">
+##INFO=<ID=AF_EUR,Number=1,Type=String,Description="no description available">
+##INFO=<ID=AF_SAS,Number=1,Type=String,Description="no description available">
+#CHROM	POS	ID	REF	ALT	QUAL	FILTER	INFO	FORMAT	Sample1
+chr1	69270	.	A	G	.	.	AF_AFR=0.360;AF_EAS=0.998;AF_EUR=0.911;AF_SAS=0.902	GT	1/1
+chr1	69897	.	T	C	.	.	AF_AFR=0.312;AF_EAS=0.777;AF_EUR=0.844;AF_SAS=0.805	GT	0/1
+chr1	325155	.	C	A	.	.	AF_AFR=0.653;AF_EAS=0.971;AF_EUR=0.769;AF_SAS=0.497	GT	1/1
+chr1	881627	.	G	A	.	.	AF_AFR=0.130;AF_EAS=0.658;AF_EUR=0.636;AF_SAS=0.565	GT	0/1
+chr1	914852	.	G	C	.	.	AF_AFR=0.249;AF_EAS=0.722;AF_EUR=0.596;AF_SAS=0.622	GT	1/1
diff --git a/bio/ngsbits/sampleancestry/wrapper.py b/bio/ngsbits/sampleancestry/wrapper.py
new file mode 100644
index 00000000000..5d6a1161f21
--- /dev/null
+++ b/bio/ngsbits/sampleancestry/wrapper.py
@@ -0,0 +1,23 @@
+# coding: utf-8
+
+"""Snakemake wrapper for NGS-bits SampleAncestry"""
+
+__author__ = "Thibault Dayris"
+__copyright__ = "Copyright 2024, Thibault Dayris"
+__email__ = "thibault.dayris@gustaveroussy.fr"
+__license__ = "MIT"
+
+from snakemake.shell import shell
+
+log = snakemake.log_fmt_shell(
+    stdout=False,
+    stderr=True,
+)
+extra = snakemake.params.get("extra", "")
+
+shell(
+    "SampleAncestry {extra}"
+    " -in {snakemake.input}"
+    " -out {snakemake.output:q}"
+    " {log}"
+)
diff --git a/test_wrappers.py b/test_wrappers.py
index 5c47f4ea9b8..cee5580e7d4 100644
--- a/test_wrappers.py
+++ b/test_wrappers.py
@@ -3579,6 +3579,20 @@ def test_nanosim_metagenome(run):
     )
 
 
+def test_ngsbits_sampleancestry(run):
+    run(
+        "bio/ngsbits/sampleancestry",
+        [
+            "snakemake",
+            "--cores",
+            "1",
+            "--use-conda",
+            "-F",
+            "ancestry.tsv",
+        ],
+    )
+
+
 def test_ngsderive(run):
     run(
         "bio/ngsderive",
@@ -5959,12 +5973,14 @@ def test_vg_autoindex_giraffe(run):
         ["snakemake", "--cores", "1", "resources/genome.dist", "--use-conda", "-F"],
     )
 
+
 def test_vg_autoindex_map(run):
     run(
         "bio/vg/autoindex",
         ["snakemake", "--cores", "1", "resources/genome.xg", "--use-conda", "-F"],
     )
 
+
 def test_vg_construct(run):
     run(
         "bio/vg/construct",