diff --git a/.github/workflows/ci_cron.yml b/.github/workflows/ci_cron.yml
index 8dcd5321..43ac5546 100644
--- a/.github/workflows/ci_cron.yml
+++ b/.github/workflows/ci_cron.yml
@@ -15,3 +15,4 @@ jobs:
           python-version: 3.9
         - macos: test-xdist
           python-version: 3.10
+        - linux: test-devdeps-xdist
diff --git a/tox.ini b/tox.ini
index 76de5ad7..27a24873 100644
--- a/tox.ini
+++ b/tox.ini
@@ -60,6 +60,7 @@ deps =
 pass_env =
     CI
 set_env =
+    devdeps: PIP_EXTRA_INDEX_URL = https://pypi.anaconda.org/scipy-wheels-nightly/simple
     jwst: CRDS_SERVER_URL=https://jwst-crds.stsci.edu
     romancal: CRDS_SERVER_URL=https://roman-crds.stsci.edu
     jwst,romancal: CRDS_PATH={package_root}/crds_cache
@@ -68,6 +69,7 @@ set_env =
 commands_pre =
     oldestdeps: minimum_dependencies stcal --filename requirements-min.txt
     oldestdeps: pip install -r requirements-min.txt
+    devdeps: pip install numpy>=0.0.dev0 scipy>=0.0.dev0 git+https://github.com/astropy/astropy -U --upgrade-strategy eager
     pip freeze
 commands =
     pytest \